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Journal Abstract Search


191 related items for PubMed ID: 27383194

  • 1. Cross-linking of lens crystallin proteins induced by tryptophan metabolites and metal ions: implications for cataract development.
    Tweeddale HJ, Hawkins CL, Janmie JF, Truscott RJ, Davies MJ.
    Free Radic Res; 2016 Oct; 50(10):1116-1130. PubMed ID: 27383194
    [Abstract] [Full Text] [Related]

  • 2. Tryptophan-derived ultraviolet filter compounds covalently bound to lens proteins are photosensitizers of oxidative damage.
    Mizdrak J, Hains PG, Truscott RJ, Jamie JF, Davies MJ.
    Free Radic Biol Med; 2008 Mar 15; 44(6):1108-19. PubMed ID: 18206985
    [Abstract] [Full Text] [Related]

  • 3. Oxidation products of 3-hydroxykynurenine bind to lens proteins: relevance for nuclear cataract.
    Aquilina JA, Carver JA, Truscott RJ.
    Exp Eye Res; 1997 May 15; 64(5):727-35. PubMed ID: 9245903
    [Abstract] [Full Text] [Related]

  • 4. 3-Hydroxykynurenine oxidizes alpha-crystallin: potential role in cataractogenesis.
    Korlimbinis A, Hains PG, Truscott RJ, Aquilina JA.
    Biochemistry; 2006 Feb 14; 45(6):1852-60. PubMed ID: 16460031
    [Abstract] [Full Text] [Related]

  • 5. Identification of 3-hydroxykynurenine bound to proteins in the human lens. A possible role in age-related nuclear cataract.
    Korlimbinis A, Truscott RJ.
    Biochemistry; 2006 Feb 14; 45(6):1950-60. PubMed ID: 16460042
    [Abstract] [Full Text] [Related]

  • 6. The presence of a human UV filter within the lens represents an oxidative stress.
    Berry Y, Truscott RJ.
    Exp Eye Res; 2001 Apr 14; 72(4):411-21. PubMed ID: 11273669
    [Abstract] [Full Text] [Related]

  • 7. Protein oxidation and loss of protease activity may lead to cataract formation in the aged lens.
    Taylor A, Davies KJ.
    Free Radic Biol Med; 1987 Apr 14; 3(6):371-7. PubMed ID: 3322949
    [Abstract] [Full Text] [Related]

  • 8. 3-Hydroxykynurenine and 3-hydroxyanthranilic acid generate hydrogen peroxide and promote alpha-crystallin cross-linking by metal ion reduction.
    Goldstein LE, Leopold MC, Huang X, Atwood CS, Saunders AJ, Hartshorn M, Lim JT, Faget KY, Muffat JA, Scarpa RC, Chylack LT, Bowden EF, Tanzi RE, Bush AI.
    Biochemistry; 2000 Jun 20; 39(24):7266-75. PubMed ID: 10852726
    [Abstract] [Full Text] [Related]

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  • 10. Changes of lens crystallins photosensitized with tryptophan metabolites.
    Ichijima H, Iwata S.
    Ophthalmic Res; 1987 Jun 20; 19(3):157-63. PubMed ID: 3658326
    [Abstract] [Full Text] [Related]

  • 11. Non-oxidative modification of lens crystallins by kynurenine: a novel post-translational protein modification with possible relevance to ageing and cataract.
    Garner B, Shaw DC, Lindner RA, Carver JA, Truscott RJ.
    Biochim Biophys Acta; 2000 Feb 09; 1476(2):265-78. PubMed ID: 10669791
    [Abstract] [Full Text] [Related]

  • 12. Tryptophan metabolites from young human lenses and the photooxidation of ascorbic acid by UVA light.
    Ortwerth BJ, Bhattacharyya J, Shipova E.
    Invest Ophthalmol Vis Sci; 2009 Jul 09; 50(7):3311-9. PubMed ID: 19264899
    [Abstract] [Full Text] [Related]

  • 13. Protein-bound kynurenine is a photosensitizer of oxidative damage.
    Parker NR, Jamie JF, Davies MJ, Truscott RJ.
    Free Radic Biol Med; 2004 Nov 01; 37(9):1479-89. PubMed ID: 15454288
    [Abstract] [Full Text] [Related]

  • 14. Protein-bound UV filters in normal human lenses: the concentration of bound UV filters equals that of free UV filters in the center of older lenses.
    Korlimbinis A, Aquilina JA, Truscott RJ.
    Invest Ophthalmol Vis Sci; 2007 Apr 01; 48(4):1718-23. PubMed ID: 17389504
    [Abstract] [Full Text] [Related]

  • 15. UVA light-excited kynurenines oxidize ascorbate and modify lens proteins through the formation of advanced glycation end products: implications for human lens aging and cataract formation.
    Linetsky M, Raghavan CT, Johar K, Fan X, Monnier VM, Vasavada AR, Nagaraj RH.
    J Biol Chem; 2014 Jun 13; 289(24):17111-23. PubMed ID: 24798334
    [Abstract] [Full Text] [Related]

  • 16. Protein oxidation and lens opacity in humans.
    Boscia F, Grattagliano I, Vendemiale G, Micelli-Ferrari T, Altomare E.
    Invest Ophthalmol Vis Sci; 2000 Aug 13; 41(9):2461-5. PubMed ID: 10937554
    [Abstract] [Full Text] [Related]

  • 17. Transition metal-catalyzed oxidation of ascorbate in human cataract extracts: possible role of advanced glycation end products.
    Saxena P, Saxena AK, Cui XL, Obrenovich M, Gudipaty K, Monnier VM.
    Invest Ophthalmol Vis Sci; 2000 May 13; 41(6):1473-81. PubMed ID: 10798665
    [Abstract] [Full Text] [Related]

  • 18. Site specific oxidation of amino acid residues in rat lens γ-crystallin induced by low-dose γ-irradiation.
    Kim I, Saito T, Fujii N, Kanamoto T, Chatake T, Fujii N.
    Biochem Biophys Res Commun; 2015 Oct 30; 466(4):622-8. PubMed ID: 26385181
    [Abstract] [Full Text] [Related]

  • 19. The Nitrite/alpha crystallin reaction: a possible mechanism in lens matrix damage.
    Paik DC, Dillon J.
    Exp Eye Res; 2000 Jan 30; 70(1):73-80. PubMed ID: 10644422
    [Abstract] [Full Text] [Related]

  • 20. Protein-bound and free UV filters in cataract lenses. The concentration of UV filters is much lower than in normal lenses.
    Korlimbinis A, Aquilina JA, Truscott RJ.
    Exp Eye Res; 2007 Aug 30; 85(2):219-25. PubMed ID: 17574241
    [Abstract] [Full Text] [Related]


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