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172 related items for PubMed ID: 27391351

  • 1. FLT3 is implicated in cytarabine transport by human equilibrative nucleoside transporter 1 in pediatric acute leukemia.
    Català A, Pastor-Anglada M, Caviedes-Cárdenas L, Malatesta R, Rives S, Vega-García N, Camós M, Fernández-Calotti P.
    Oncotarget; 2016 Aug 02; 7(31):49786-49799. PubMed ID: 27391351
    [Abstract] [Full Text] [Related]

  • 2. Differential mRNA expression of Ara-C-metabolizing enzymes explains Ara-C sensitivity in MLL gene-rearranged infant acute lymphoblastic leukemia.
    Stam RW, den Boer ML, Meijerink JP, Ebus ME, Peters GJ, Noordhuis P, Janka-Schaub GE, Armstrong SA, Korsmeyer SJ, Pieters R.
    Blood; 2003 Feb 15; 101(4):1270-6. PubMed ID: 12406912
    [Abstract] [Full Text] [Related]

  • 3. Expression of the nucleoside transporters hENT1 (SLC29) and hCNT1 (SLC28) in pediatric acute myeloid leukemia.
    Jaramillo AC, Hubeek I, Broekhuizen R, Pastor-Anglada M, Kaspers GJL, Jansen G, Cloos J, Peters GJ.
    Nucleosides Nucleotides Nucleic Acids; 2020 Feb 15; 39(10-12):1379-1388. PubMed ID: 32312148
    [Abstract] [Full Text] [Related]

  • 4. Effect of hypoxia on human equilibrative nucleoside transporters hENT1 and hENT2 in breast cancer.
    Krys D, Hamann I, Wuest M, Wuest F.
    FASEB J; 2019 Dec 15; 33(12):13837-13851. PubMed ID: 31601121
    [Abstract] [Full Text] [Related]

  • 5. FMS-like tyrosine kinase 3 (FLT3) modulates key enzymes of nucleotide metabolism implicated in cytarabine responsiveness in pediatric acute leukemia.
    Perelló-Reus CM, Català A, Caviedes-Cárdenas L, Vega-García N, Camós M, Pérez-Torras S, Pastor-Anglada M.
    Pharmacol Res; 2020 Jan 15; 151():104556. PubMed ID: 31778791
    [Abstract] [Full Text] [Related]

  • 6. Cytosine arabinoside-metabolizing enzyme genes are underexpressed in children with MLL gene-rearranged acute lymphoblastic leukemia.
    Mata JF, Scrideli CA, Queiroz RP, Mori BO, Emerenciano M, Pombo-de-Oliveira MS, Tone LG.
    Braz J Med Biol Res; 2006 Nov 15; 39(11):1417-23. PubMed ID: 17146554
    [Abstract] [Full Text] [Related]

  • 7. Flt3 does not play a critical role in murine myeloid leukemias induced by MLL fusion genes.
    Albouhair S, Morgado E, Lavau C.
    PLoS One; 2013 Nov 15; 8(8):e72261. PubMed ID: 23977266
    [Abstract] [Full Text] [Related]

  • 8. Cellular localization and functional characterization of the equilibrative nucleoside transporters of antitumor nucleosides.
    Endo Y, Obata T, Murata D, Ito M, Sakamoto K, Fukushima M, Yamasaki Y, Yamada Y, Natsume N, Sasaki T.
    Cancer Sci; 2007 Oct 15; 98(10):1633-7. PubMed ID: 17711502
    [Abstract] [Full Text] [Related]

  • 9. Targeting FLT3 in primary MLL-gene-rearranged infant acute lymphoblastic leukemia.
    Stam RW, den Boer ML, Schneider P, Nollau P, Horstmann M, Beverloo HB, van der Voort E, Valsecchi MG, de Lorenzo P, Sallan SE, Armstrong SA, Pieters R.
    Blood; 2005 Oct 01; 106(7):2484-90. PubMed ID: 15956279
    [Abstract] [Full Text] [Related]

  • 10. Expression and hepatobiliary transport characteristics of the concentrative and equilibrative nucleoside transporters in sandwich-cultured human hepatocytes.
    Govindarajan R, Endres CJ, Whittington D, LeCluyse E, Pastor-Anglada M, Tse CM, Unadkat JD.
    Am J Physiol Gastrointest Liver Physiol; 2008 Sep 01; 295(3):G570-80. PubMed ID: 18635603
    [Abstract] [Full Text] [Related]

  • 11. The role of human nucleoside transporters in cellular uptake of 4'-thio-beta-D-arabinofuranosylcytosine and beta-D-arabinosylcytosine.
    Clarke ML, Damaraju VL, Zhang J, Mowles D, Tackaberry T, Lang T, Smith KM, Young JD, Tomkinson B, Cass CE.
    Mol Pharmacol; 2006 Jul 01; 70(1):303-10. PubMed ID: 16617163
    [Abstract] [Full Text] [Related]

  • 12. Targeting PRMT1-mediated FLT3 methylation disrupts maintenance of MLL-rearranged acute lymphoblastic leukemia.
    Zhu Y, He X, Lin YC, Dong H, Zhang L, Chen X, Wang Z, Shen Y, Li M, Wang H, Sun J, Nguyen LX, Zhang H, Jiang W, Yang Y, Chen J, Müschen M, Chen CW, Konopleva MY, Sun W, Jin J, Carlesso N, Marcucci G, Luo Y, Li L.
    Blood; 2019 Oct 10; 134(15):1257-1268. PubMed ID: 31395602
    [Abstract] [Full Text] [Related]

  • 13. Equilibrative nucleoside transporter 2 is expressed in human umbilical vein endothelium, but is not involved in the inhibition of adenosine transport induced by hyperglycaemia.
    Aguayo C, Casado J, González M, Pearson JD, Martín RS, Casanello P, Pastor-Anglada M, Sobrevia L.
    Placenta; 2005 Oct 10; 26(8-9):641-53. PubMed ID: 16085043
    [Abstract] [Full Text] [Related]

  • 14. The role of human equilibrative nucleoside transporter 1 on the cellular transport of the DNA methyltransferase inhibitors 5-azacytidine and CP-4200 in human leukemia cells.
    Hummel-Eisenbeiss J, Hascher A, Hals PA, Sandvold ML, Müller-Tidow C, Lyko F, Rius M.
    Mol Pharmacol; 2013 Sep 10; 84(3):438-50. PubMed ID: 23814180
    [Abstract] [Full Text] [Related]

  • 15. Glycine 154 of the equilibrative nucleoside transporter, hENT1, is important for nucleoside transport and for conferring sensitivity to the inhibitors nitrobenzylthioinosine, dipyridamole, and dilazep.
    SenGupta DJ, Unadkat JD.
    Biochem Pharmacol; 2004 Feb 01; 67(3):453-8. PubMed ID: 15037197
    [Abstract] [Full Text] [Related]

  • 16. Insulin restores glucose inhibition of adenosine transport by increasing the expression and activity of the equilibrative nucleoside transporter 2 in human umbilical vein endothelium.
    Muñoz G, San Martín R, Farías M, Cea L, Vecchiola A, Casanello P, Sobrevia L.
    J Cell Physiol; 2006 Dec 01; 209(3):826-35. PubMed ID: 16924660
    [Abstract] [Full Text] [Related]

  • 17. Transport of A1 adenosine receptor agonist tecadenoson by human and mouse nucleoside transporters: evidence for blood-brain barrier transport by murine equilibrative nucleoside transporter 1 mENT1.
    Lepist EI, Damaraju VL, Zhang J, Gati WP, Yao SY, Smith KM, Karpinski E, Young JD, Leung KH, Cass CE.
    Drug Metab Dispos; 2013 Apr 01; 41(4):916-22. PubMed ID: 23388705
    [Abstract] [Full Text] [Related]

  • 18. Inhibition of FLT3 in MLL. Validation of a therapeutic target identified by gene expression based classification.
    Armstrong SA, Kung AL, Mabon ME, Silverman LB, Stam RW, Den Boer ML, Pieters R, Kersey JH, Sallan SE, Fletcher JA, Golub TR, Griffin JD, Korsmeyer SJ.
    Cancer Cell; 2003 Feb 01; 3(2):173-83. PubMed ID: 12620411
    [Abstract] [Full Text] [Related]

  • 19. Two distinct molecular mechanisms underlying cytarabine resistance in human leukemic cells.
    Cai J, Damaraju VL, Groulx N, Mowles D, Peng Y, Robins MJ, Cass CE, Gros P.
    Cancer Res; 2008 Apr 01; 68(7):2349-57. PubMed ID: 18381442
    [Abstract] [Full Text] [Related]

  • 20. FLT3-ITD induces ara-C resistance in myeloid leukemic cells through the repression of the ENT1 expression.
    Jin G, Matsushita H, Asai S, Tsukamoto H, Ono R, Nosaka T, Yahata T, Takahashi S, Miyachi H.
    Biochem Biophys Res Commun; 2009 Dec 18; 390(3):1001-6. PubMed ID: 19853583
    [Abstract] [Full Text] [Related]

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