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171 related items for PubMed ID: 27402187

  • 1. Functional and cellular consequences of covalent target protein modification by furan in rat liver.
    Ramm S, Limbeck E, Mally A.
    Toxicology; 2016 Jun 15; 361-362():49-61. PubMed ID: 27402187
    [Abstract] [Full Text] [Related]

  • 2. Identification and pathway mapping of furan target proteins reveal mitochondrial energy production and redox regulation as critical targets of furan toxicity.
    Moro S, Chipman JK, Antczak P, Turan N, Dekant W, Falciani F, Mally A.
    Toxicol Sci; 2012 Apr 15; 126(2):336-52. PubMed ID: 22240984
    [Abstract] [Full Text] [Related]

  • 3. Hepatobiliary toxicity of furan: identification of furan metabolites in bile of male f344/n rats.
    Hamberger C, Kellert M, Schauer UM, Dekant W, Mally A.
    Drug Metab Dispos; 2010 Oct 15; 38(10):1698-706. PubMed ID: 20639435
    [Abstract] [Full Text] [Related]

  • 4. Characterization of amino acid and glutathione adducts of cis-2-butene-1,4-dial, a reactive metabolite of furan.
    Chen LJ, Hecht SS, Peterson LA.
    Chem Res Toxicol; 1997 Aug 15; 10(8):866-74. PubMed ID: 9282835
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  • 5. Toxicogenomic assessment of liver responses following subchronic exposure to furan in Fischer F344 rats.
    Dong H, Gill S, Curran IH, Williams A, Kuo B, Wade MG, Yauk CL.
    Arch Toxicol; 2016 Jun 15; 90(6):1351-67. PubMed ID: 26194646
    [Abstract] [Full Text] [Related]

  • 6. New insights into the molecular mechanisms of chemical carcinogenesis: In vivo adduction of histone H2B by a reactive metabolite of the chemical carcinogen furan.
    Nunes J, Martins IL, Charneira C, Pogribny IP, de Conti A, Beland FA, Marques MM, Jacob CC, Antunes AMM.
    Toxicol Lett; 2016 Dec 15; 264():106-113. PubMed ID: 27825936
    [Abstract] [Full Text] [Related]

  • 7. Glutathione trapping to measure microsomal oxidation of furan to cis-2-butene-1,4-dial.
    Peterson LA, Cummings ME, Vu CC, Matter BA.
    Drug Metab Dispos; 2005 Oct 15; 33(10):1453-8. PubMed ID: 16006568
    [Abstract] [Full Text] [Related]

  • 8. Evaluation of serum and liver toxicokinetics for furan and liver DNA adduct formation in male Fischer 344 rats.
    Churchwell MI, Scheri RC, Von Tungeln LS, Gamboa da Costa G, Beland FA, Doerge DR.
    Food Chem Toxicol; 2015 Dec 15; 86():1-8. PubMed ID: 26364877
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  • 11. Exploration of the cellular effects of the high-dose, long-term exposure to coffee roasting product furan and its by-product cis-2-butene-1,4-dial on human and rat hepatocytes.
    Teodoro JS, Silva R, Aguiar A, Sobral AJFN, Rolo AP, Palmeira CM.
    Toxicol Mech Methods; 2020 Sep 15; 30(7):536-545. PubMed ID: 32544017
    [Abstract] [Full Text] [Related]

  • 12. Prediction of furan pharmacokinetics from hepatocyte studies: comparison of bioactivation and hepatic dosimetry in rats, mice, and humans.
    Kedderis GL, Held SD.
    Toxicol Appl Pharmacol; 1996 Sep 15; 140(1):124-30. PubMed ID: 8806878
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  • 13. Furan-induced transcriptomic and gene-specific DNA methylation changes in the livers of Fischer 344 rats in a 2-year carcinogenicity study.
    Tryndyak V, de Conti A, Doerge DR, Olson GR, Beland FA, Pogribny IP.
    Arch Toxicol; 2017 Mar 15; 91(3):1233-1243. PubMed ID: 27387713
    [Abstract] [Full Text] [Related]

  • 14. Dictamnine-induced hepatotoxicity in mice: the role of metabolic activation of furan.
    Shi F, Pan H, Cui B, Li Y, Huang L, Lu Y.
    Toxicol Appl Pharmacol; 2019 Feb 01; 364():68-76. PubMed ID: 30578885
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  • 16. In vivo genotoxicity of furan in F344 rats at cancer bioassay doses.
    Ding W, Petibone DM, Latendresse JR, Pearce MG, Muskhelishvili L, White GA, Chang CW, Mittelstaedt RA, Shaddock JG, McDaniel LP, Doerge DR, Morris SM, Bishop ME, Manjanatha MG, Aidoo A, Heflich RH.
    Toxicol Appl Pharmacol; 2012 Jun 01; 261(2):164-71. PubMed ID: 22507866
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  • 17. Case study on the utility of hepatic global gene expression profiling in the risk assessment of the carcinogen furan.
    Jackson AF, Williams A, Recio L, Waters MD, Lambert IB, Yauk CL.
    Toxicol Appl Pharmacol; 2014 Jan 01; 274(1):63-77. PubMed ID: 24183702
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  • 18. Degraded protein adducts of cis-2-butene-1,4-dial are urinary and hepatocyte metabolites of furan.
    Lu D, Sullivan MM, Phillips MB, Peterson LA.
    Chem Res Toxicol; 2009 Jun 01; 22(6):997-1007. PubMed ID: 19441776
    [Abstract] [Full Text] [Related]

  • 19. Furan-induced cytolethality in isolated rat hepatocytes: correspondence with in vivo dosimetry.
    Carfagna MA, Held SD, Kedderis GL.
    Toxicol Appl Pharmacol; 1993 Dec 01; 123(2):265-73. PubMed ID: 8248933
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  • 20. Furan-induced dose-response relationships for liver cytotoxicity, cell proliferation, and tumorigenicity (furan-induced liver tumorigenicity).
    Moser GJ, Foley J, Burnett M, Goldsworthy TL, Maronpot R.
    Exp Toxicol Pathol; 2009 Mar 01; 61(2):101-11. PubMed ID: 18809303
    [Abstract] [Full Text] [Related]

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