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Journal Abstract Search

283 related items for PubMed ID: 27405777

  • 1. Forced chromatin looping raises fetal hemoglobin in adult sickle cells to higher levels than pharmacologic inducers.
    Breda L, Motta I, Lourenco S, Gemmo C, Deng W, Rupon JW, Abdulmalik OY, Manwani D, Blobel GA, Rivella S.
    Blood; 2016 Aug 25; 128(8):1139-43. PubMed ID: 27405777
    [Abstract] [Full Text] [Related]

  • 2. Inhibition of G9a methyltransferase stimulates fetal hemoglobin production by facilitating LCR/γ-globin looping.
    Krivega I, Byrnes C, de Vasconcellos JF, Lee YT, Kaushal M, Dean A, Miller JL.
    Blood; 2015 Jul 30; 126(5):665-72. PubMed ID: 25979948
    [Abstract] [Full Text] [Related]

  • 3. Bach1 inhibitor HPP-D mediates γ-globin gene activation in sickle erythroid progenitors.
    Palani CD, Zhu X, Alagar M, Attucks OC, Pace BS.
    Blood Cells Mol Dis; 2024 Jan 30; 104():102792. PubMed ID: 37633023
    [Abstract] [Full Text] [Related]

  • 4. Reactivation of developmentally silenced globin genes by forced chromatin looping.
    Deng W, Rupon JW, Krivega I, Breda L, Motta I, Jahn KS, Reik A, Gregory PD, Rivella S, Dean A, Blobel GA.
    Cell; 2014 Aug 14; 158(4):849-860. PubMed ID: 25126789
    [Abstract] [Full Text] [Related]

  • 5. Controlling long-range genomic interactions at a native locus by targeted tethering of a looping factor.
    Deng W, Lee J, Wang H, Miller J, Reik A, Gregory PD, Dean A, Blobel GA.
    Cell; 2012 Jun 08; 149(6):1233-44. PubMed ID: 22682246
    [Abstract] [Full Text] [Related]

  • 6. A zinc-finger transcriptional activator designed to interact with the gamma-globin gene promoters enhances fetal hemoglobin production in primary human adult erythroblasts.
    Wilber A, Tschulena U, Hargrove PW, Kim YS, Persons DA, Barbas CF, Nienhuis AW.
    Blood; 2010 Apr 15; 115(15):3033-41. PubMed ID: 20190190
    [Abstract] [Full Text] [Related]

  • 7. Chromatin looping as a target for altering erythroid gene expression.
    Krivega I, Dean A.
    Ann N Y Acad Sci; 2016 Mar 15; 1368(1):31-9. PubMed ID: 26918894
    [Abstract] [Full Text] [Related]

  • 8. Role of LDB1 in the transition from chromatin looping to transcription activation.
    Krivega I, Dale RK, Dean A.
    Genes Dev; 2014 Jun 15; 28(12):1278-90. PubMed ID: 24874989
    [Abstract] [Full Text] [Related]

  • 9. Embryonic erythropoiesis and hemoglobin switching require transcriptional repressor ETO2 to modulate chromatin organization.
    Guo X, Plank-Bazinet J, Krivega I, Dale RK, Dean A.
    Nucleic Acids Res; 2020 Oct 09; 48(18):10226-10240. PubMed ID: 32960220
    [Abstract] [Full Text] [Related]

  • 10. EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression.
    Renneville A, Van Galen P, Canver MC, McConkey M, Krill-Burger JM, Dorfman DM, Holson EB, Bernstein BE, Orkin SH, Bauer DE, Ebert BL.
    Blood; 2015 Oct 15; 126(16):1930-9. PubMed ID: 26320100
    [Abstract] [Full Text] [Related]

  • 11. Forced enhancer-promoter rewiring to alter gene expression in animal models.
    Peslak SA, Demirci S, Chandra V, Ryu B, Bhardwaj SK, Jiang J, Rupon JW, Throm RE, Uchida N, Leonard A, Essawi K, Bonifacino AC, Krouse AE, Linde NS, Donahue RE, Ferrara F, Wielgosz M, Abdulmalik O, Hamagami N, Germino-Watnick P, Le A, Chu R, Hinds M, Weiss MJ, Tong W, Tisdale JF, Blobel GA.
    Mol Ther Nucleic Acids; 2023 Mar 14; 31():452-465. PubMed ID: 36852088
    [Abstract] [Full Text] [Related]

  • 12. Dimethyl fumarate increases fetal hemoglobin, provides heme detoxification, and corrects anemia in sickle cell disease.
    Krishnamoorthy S, Pace B, Gupta D, Sturtevant S, Li B, Makala L, Brittain J, Moore N, Vieira BF, Thullen T, Stone I, Li H, Hobbs WE, Light DR.
    JCI Insight; 2017 Oct 19; 2(20):. PubMed ID: 29046485
    [Abstract] [Full Text] [Related]

  • 13. Reactivation of Fetal Hemoglobin for Treating β-Thalassemia and Sickle Cell Disease.
    Cui S, Engel JD.
    Adv Exp Med Biol; 2017 Oct 19; 1013():177-202. PubMed ID: 29127681
    [Abstract] [Full Text] [Related]

  • 14. Monomethylfumarate induces γ-globin expression and fetal hemoglobin production in cultured human retinal pigment epithelial (RPE) and erythroid cells, and in intact retina.
    Promsote W, Makala L, Li B, Smith SB, Singh N, Ganapathy V, Pace BS, Martin PM.
    Invest Ophthalmol Vis Sci; 2014 May 13; 55(8):5382-93. PubMed ID: 24825111
    [Abstract] [Full Text] [Related]

  • 15. Pharmacological Induction of Human Fetal Globin Gene in Hydroxyurea-Resistant Primary Adult Erythroid Cells.
    Chou YC, Chen RL, Lai ZS, Song JS, Chao YS, Shen CK.
    Mol Cell Biol; 2015 Jul 13; 35(14):2541-53. PubMed ID: 25986606
    [Abstract] [Full Text] [Related]

  • 16. Correction of murine sickle cell disease using gamma-globin lentiviral vectors to mediate high-level expression of fetal hemoglobin.
    Pestina TI, Hargrove PW, Jay D, Gray JT, Boyd KM, Persons DA.
    Mol Ther; 2009 Feb 13; 17(2):245-52. PubMed ID: 19050697
    [Abstract] [Full Text] [Related]

  • 17. Robust erythroid differentiation system for rhesus hematopoietic progenitor cells allowing preclinical screening of genetic treatment strategies for the hemoglobinopathies.
    Demirci S, Bhardwaj SK, Uchida N, Haro-Mora JJ, Ryu B, Blobel GA, Tisdale JF.
    Cytotherapy; 2018 Oct 13; 20(10):1278-1287. PubMed ID: 30249524
    [Abstract] [Full Text] [Related]

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