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303 related items for PubMed ID: 27436361

  • 1. ROCK2 signaling is required to induce a subset of T follicular helper cells through opposing effects on STATs in autoimmune settings.
    Weiss JM, Chen W, Nyuydzefe MS, Trzeciak A, Flynn R, Tonra JR, Marusic S, Blazar BR, Waksal SD, Zanin-Zhorov A.
    Sci Signal; 2016 Jul 19; 9(437):ra73. PubMed ID: 27436361
    [Abstract] [Full Text] [Related]

  • 2. ROCK2, but not ROCK1 interacts with phosphorylated STAT3 and co-occupies TH17/TFH gene promoters in TH17-activated human T cells.
    Chen W, Nyuydzefe MS, Weiss JM, Zhang J, Waksal SD, Zanin-Zhorov A.
    Sci Rep; 2018 Nov 09; 8(1):16636. PubMed ID: 30413785
    [Abstract] [Full Text] [Related]

  • 3. Toll-like receptor 7 agonist imiquimod prevents the progression of SLE in MRL/lpr mice via inhibiting the differentiation of T follicular helper cells.
    Duan X, Shen C, Zhang X, Wu L, Chen J, Ma B, Wang Q, Sun P, Lan Y, Su C.
    Int Immunopharmacol; 2020 Mar 09; 80():106239. PubMed ID: 32007709
    [Abstract] [Full Text] [Related]

  • 4. Conversion of T Follicular Helper Cells to T Follicular Regulatory Cells by Interleukin-2 Through Transcriptional Regulation in Systemic Lupus Erythematosus.
    Hao H, Nakayamada S, Yamagata K, Ohkubo N, Iwata S, Inoue Y, Zhang M, Zhang T, Kanda Satoh Y, Shan Y, Otsuka T, Tanaka Y.
    Arthritis Rheumatol; 2021 Jan 09; 73(1):132-142. PubMed ID: 32720470
    [Abstract] [Full Text] [Related]

  • 5. Therapeutic effects of artesunate on lupus-prone MRL/lpr mice are dependent on T follicular helper cell differentiation and activation of JAK2-STAT3 signaling pathway.
    Dang WZ, Li H, Jiang B, Nandakumar KS, Liu KF, Liu LX, Yu XC, Tan HJ, Zhou C.
    Phytomedicine; 2019 Sep 09; 62():152965. PubMed ID: 31129432
    [Abstract] [Full Text] [Related]

  • 6. Modulation of PKM2 inhibits follicular helper T cell differentiation and ameliorates inflammation in lupus-prone mice.
    Lin M, Huang L, Huang J, Yu J, Yang X, Yang J.
    J Autoimmun; 2024 May 09; 145():103198. PubMed ID: 38428341
    [Abstract] [Full Text] [Related]

  • 7. Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism.
    Flynn R, Paz K, Du J, Reichenbach DK, Taylor PA, Panoskaltsis-Mortari A, Vulic A, Luznik L, MacDonald KK, Hill GR, Nyuydzefe MS, Weiss JM, Chen W, Trzeciak A, Serody JS, Aguilar EG, Murphy WJ, Maillard I, Munn D, Koreth J, Cutler CS, Antin JH, Ritz J, Waksal SD, Zanin-Zhorov A, Blazar BR.
    Blood; 2016 Apr 28; 127(17):2144-54. PubMed ID: 26983850
    [Abstract] [Full Text] [Related]

  • 8. An Inhibitory Role for the Transcription Factor Stat3 in Controlling IL-4 and Bcl6 Expression in Follicular Helper T Cells.
    Wu H, Xu LL, Teuscher P, Liu H, Kaplan MH, Dent AL.
    J Immunol; 2015 Sep 01; 195(5):2080-9. PubMed ID: 26188063
    [Abstract] [Full Text] [Related]

  • 9. Bcl6 promotes follicular helper T-cell differentiation and PD-1 expression in a Blimp1-independent manner in mice.
    Xie MM, Koh BH, Hollister K, Wu H, Sun J, Kaplan MH, Dent AL.
    Eur J Immunol; 2017 Jul 01; 47(7):1136-1141. PubMed ID: 28586108
    [Abstract] [Full Text] [Related]

  • 10. E4BP4-mediated inhibition of T follicular helper cell differentiation is compromised in autoimmune diseases.
    Wang Z, Zhao M, Yin J, Liu L, Hu L, Huang Y, Liu A, Ouyang J, Min X, Rao S, Zhou W, Wu H, Yoshimura A, Lu Q.
    J Clin Invest; 2020 Jul 01; 130(7):3717-3733. PubMed ID: 32191636
    [Abstract] [Full Text] [Related]

  • 11. Genome-wide Analysis Identifies Bcl6-Controlled Regulatory Networks during T Follicular Helper Cell Differentiation.
    Liu X, Lu H, Chen T, Nallaparaju KC, Yan X, Tanaka S, Ichiyama K, Zhang X, Zhang L, Wen X, Tian Q, Bian XW, Jin W, Wei L, Dong C.
    Cell Rep; 2016 Feb 23; 14(7):1735-1747. PubMed ID: 26876184
    [Abstract] [Full Text] [Related]

  • 12. Deficiency of CBL and CBLB ubiquitin ligases leads to hyper T follicular helper cell responses and lupus by reducing BCL6 degradation.
    Li X, Sun W, Huang M, Gong L, Zhang X, Zhong L, Calderon V, Bian Z, He Y, Suh WK, Li Y, Song T, Zou Y, Lian ZX, Gu H.
    Immunity; 2024 Jul 09; 57(7):1603-1617.e7. PubMed ID: 38761804
    [Abstract] [Full Text] [Related]

  • 13. Bcl6 middle domain repressor function is required for T follicular helper cell differentiation and utilizes the corepressor MTA3.
    Nance JP, Bélanger S, Johnston RJ, Hu JK, Takemori T, Crotty S.
    Proc Natl Acad Sci U S A; 2015 Oct 27; 112(43):13324-9. PubMed ID: 26460037
    [Abstract] [Full Text] [Related]

  • 14. Sirtuin 1 overexpression contributes to the expansion of follicular helper T cells in systemic lupus erythematosus and may serve as an accessible therapeutic target.
    He L, Liao W, Wang X, Wang L, Liang Q, Jiang L, Yi W, Luo S, Liu Y, Qiu X, Li Y, Liu J, Wu H, Zhao M, Long H, Lu Q.
    Rheumatology (Oxford); 2024 May 03; 63(6):1699-1709. PubMed ID: 37665721
    [Abstract] [Full Text] [Related]

  • 15. Expansion of T follicular helper-T helper 1 like cells through epigenetic regulation by signal transducer and activator of transcription factors.
    Ma X, Nakayamada S, Kubo S, Sakata K, Yamagata K, Miyazaki Y, Yoshikawa M, Kitanaga Y, Zhang M, Tanaka Y.
    Ann Rheum Dis; 2018 Sep 03; 77(9):1354-1361. PubMed ID: 29853448
    [Abstract] [Full Text] [Related]

  • 16. The mTORC1-4E-BP-eIF4E axis controls de novo Bcl6 protein synthesis in T cells and systemic autoimmunity.
    Yi W, Gupta S, Ricker E, Manni M, Jessberger R, Chinenov Y, Molina H, Pernis AB.
    Nat Commun; 2017 Aug 15; 8(1):254. PubMed ID: 28811467
    [Abstract] [Full Text] [Related]

  • 17. Circulating CXCR5+CD4+helper T cells in systemic lupus erythematosus patients share phenotypic properties with germinal center follicular helper T cells and promote antibody production.
    Zhang X, Lindwall E, Gauthier C, Lyman J, Spencer N, Alarakhia A, Fraser A, Ing S, Chen M, Webb-Detiege T, Zakem J, Davis W, Choi YS, Quinet R.
    Lupus; 2015 Aug 15; 24(9):909-17. PubMed ID: 25654980
    [Abstract] [Full Text] [Related]

  • 18. Molecular Control of Follicular Helper T cell Development and Differentiation.
    Wu H, Deng Y, Zhao M, Zhang J, Zheng M, Chen G, Li L, He Z, Lu Q.
    Front Immunol; 2018 Aug 15; 9():2470. PubMed ID: 30410493
    [Abstract] [Full Text] [Related]

  • 19. Control of Germinal Center Localization and Lineage Stability of Follicular Regulatory T Cells by the Blimp1 Transcription Factor.
    Shen E, Rabe H, Luo L, Wang L, Wang Q, Yin J, Yang X, Liu W, Sido JM, Nakagawa H, Ao L, Kim HJ, Cantor H, Leavenworth JW.
    Cell Rep; 2019 Nov 12; 29(7):1848-1861.e6. PubMed ID: 31722202
    [Abstract] [Full Text] [Related]

  • 20. STAT5 is a potent negative regulator of TFH cell differentiation.
    Johnston RJ, Choi YS, Diamond JA, Yang JA, Crotty S.
    J Exp Med; 2012 Feb 13; 209(2):243-50. PubMed ID: 22271576
    [Abstract] [Full Text] [Related]

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