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Journal Abstract Search

951 related items for PubMed ID: 27456392

  • 1. Activation of the AMPK/Sirt1 pathway by a leucine-metformin combination increases insulin sensitivity in skeletal muscle, and stimulates glucose and lipid metabolism and increases life span in Caenorhabditis elegans.
    Banerjee J, Bruckbauer A, Zemel MB.
    Metabolism; 2016 Nov; 65(11):1679-1691. PubMed ID: 27456392
    [Abstract] [Full Text] [Related]

  • 2. Leucine amplifies the effects of metformin on insulin sensitivity and glycemic control in diet-induced obese mice.
    Fu L, Bruckbauer A, Li F, Cao Q, Cui X, Wu R, Shi H, Zemel MB, Xue B.
    Metabolism; 2015 Jul; 64(7):845-56. PubMed ID: 25858853
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  • 3. Activation of SIRT1 by L-serine increases fatty acid oxidation and reverses insulin resistance in C2C12 myotubes.
    Sim WC, Kim DG, Lee W, Sim H, Choi YJ, Lee BH.
    Cell Biol Toxicol; 2019 Oct; 35(5):457-470. PubMed ID: 30721374
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  • 4. Genetic downregulation of AMPK-alpha isoforms uncovers the mechanism by which metformin decreases FA uptake and oxidation in skeletal muscle cells.
    Bogachus LD, Turcotte LP.
    Am J Physiol Cell Physiol; 2010 Dec; 299(6):C1549-61. PubMed ID: 20844250
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  • 5. Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation.
    Tomas E, Tsao TS, Saha AK, Murrey HE, Zhang Cc Cc, Itani SI, Lodish HF, Ruderman NB.
    Proc Natl Acad Sci U S A; 2002 Dec 10; 99(25):16309-13. PubMed ID: 12456889
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  • 7. Yhhu981, a novel compound, stimulates fatty acid oxidation via the activation of AMPK and ameliorates lipid metabolism disorder in ob/ob mice.
    Zeng HL, Huang SL, Xie FC, Zeng LM, Hu YH, Leng Y.
    Acta Pharmacol Sin; 2015 Mar 10; 36(3):343-52. PubMed ID: 25732571
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  • 8. Polydatin Improves Glucose and Lipid Metabolisms in Insulin-Resistant HepG2 Cells through the AMPK Pathway.
    Hao J, Huang K, Chen C, Liang Y, Wang Y, Zhang X, Huang H.
    Biol Pharm Bull; 2018 Mar 10; 41(6):891-898. PubMed ID: 29863077
    [Abstract] [Full Text] [Related]

  • 9. Telmisartan ameliorates insulin sensitivity by activating the AMPK/SIRT1 pathway in skeletal muscle of obese db/db mice.
    Shiota A, Shimabukuro M, Fukuda D, Soeki T, Sato H, Uematsu E, Hirata Y, Kurobe H, Maeda N, Sakaue H, Masuzaki H, Shimomura I, Sata M.
    Cardiovasc Diabetol; 2012 Nov 08; 11():139. PubMed ID: 23137106
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  • 10. Short-term adenosine monophosphate-activated protein kinase activator 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside treatment increases the sirtuin 1 protein expression in skeletal muscle.
    Suwa M, Nakano H, Radak Z, Kumagai S.
    Metabolism; 2011 Mar 08; 60(3):394-403. PubMed ID: 20362304
    [Abstract] [Full Text] [Related]

  • 11. Genistein stimulates fatty acid oxidation in a leptin receptor-independent manner through the JAK2-mediated phosphorylation and activation of AMPK in skeletal muscle.
    Palacios-González B, Zarain-Herzberg A, Flores-Galicia I, Noriega LG, Alemán-Escondrillas G, Zariñan T, Ulloa-Aguirre A, Torres N, Tovar AR.
    Biochim Biophys Acta; 2014 Jan 08; 1841(1):132-40. PubMed ID: 24013029
    [Abstract] [Full Text] [Related]

  • 12. Nutrient Excess and AMPK Downregulation in Incubated Skeletal Muscle and Muscle of Glucose Infused Rats.
    Coughlan KA, Balon TW, Valentine RJ, Petrocelli R, Schultz V, Brandon A, Cooney GJ, Kraegen EW, Ruderman NB, Saha AK.
    PLoS One; 2015 Jan 08; 10(5):e0127388. PubMed ID: 25996822
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  • 13. Patchouli alcohol ameliorates skeletal muscle insulin resistance and NAFLD via AMPK/SIRT1-mediated suppression of inflammation.
    Pyun DH, Kim TJ, Park SY, Lee HJ, Abd El-Aty AM, Jeong JH, Jung TW.
    Mol Cell Endocrinol; 2021 Dec 01; 538():111464. PubMed ID: 34601002
    [Abstract] [Full Text] [Related]

  • 14. Bioactive compounds from Artemisia dracunculus L. activate AMPK signaling in skeletal muscle.
    Vandanmagsar B, Yu Y, Simmler C, Dang TN, Kuhn P, Poulev A, Ribnicky DM, Pauli GF, Floyd ZE.
    Biomed Pharmacother; 2021 Nov 01; 143():112188. PubMed ID: 34563947
    [Abstract] [Full Text] [Related]

  • 15. Leucine supplementation increases SIRT1 expression and prevents mitochondrial dysfunction and metabolic disorders in high-fat diet-induced obese mice.
    Li H, Xu M, Lee J, He C, Xie Z.
    Am J Physiol Endocrinol Metab; 2012 Nov 15; 303(10):E1234-44. PubMed ID: 22967499
    [Abstract] [Full Text] [Related]

  • 16. Modulation of Energy Sensing by Leucine Synergy with Natural Sirtuin Activators: Effects on Health Span.
    Zemel MB.
    J Med Food; 2020 Nov 15; 23(11):1129-1135. PubMed ID: 32758058
    [Abstract] [Full Text] [Related]

  • 17. Metformin overcomes high glucose-induced insulin resistance of podocytes by pleiotropic effects on SIRT1 and AMPK.
    Rogacka D, Audzeyenka I, Rychłowski M, Rachubik P, Szrejder M, Angielski S, Piwkowska A.
    Biochim Biophys Acta Mol Basis Dis; 2018 Jan 15; 1864(1):115-125. PubMed ID: 29032153
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  • 18. Metformin alleviates hepatosteatosis by restoring SIRT1-mediated autophagy induction via an AMP-activated protein kinase-independent pathway.
    Song YM, Lee YH, Kim JW, Ham DS, Kang ES, Cha BS, Lee HC, Lee BW.
    Autophagy; 2015 Jan 15; 11(1):46-59. PubMed ID: 25484077
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