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Journal Abstract Search

306 related items for PubMed ID: 27464750

  • 1. Curative ex vivo liver-directed gene therapy in a pig model of hereditary tyrosinemia type 1.
    Hickey RD, Mao SA, Glorioso J, Elgilani F, Amiot B, Chen H, Rinaldo P, Marler R, Jiang H, DeGrado TR, Suksanpaisan L, O'Connor MK, Freeman BL, Ibrahim SH, Peng KW, Harding CO, Ho CS, Grompe M, Ikeda Y, Lillegard JB, Russell SJ, Nyberg SL.
    Sci Transl Med; 2016 Jul 27; 8(349):349ra99. PubMed ID: 27464750
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  • 3. Autologous Gene and Cell Therapy Provides Safe and Long-Term Curative Therapy in A Large Pig Model of Hereditary Tyrosinemia Type 1.
    Hickey RD, Nicolas CT, Allen K, Mao S, Elgilani F, Glorioso J, Amiot B, VanLith C, Guthman R, Du Z, Chen H, Harding CO, Kaiser RA, Nyberg SL, Lillegard JB.
    Cell Transplant; 2019 Jan 27; 28(1):79-88. PubMed ID: 30477316
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  • 5. Fumarylacetoacetate Hydrolase Knock-out Rabbit Model for Hereditary Tyrosinemia Type 1.
    Li L, Zhang Q, Yang H, Zou Q, Lai C, Jiang F, Zhao P, Luo Z, Yang J, Chen Q, Wang Y, Newsome PN, Frampton J, Maxwell PH, Li W, Chen S, Wang D, Siu TS, Tam S, Tse HF, Qin B, Bao X, Esteban MA, Lai L.
    J Biol Chem; 2017 Mar 17; 292(11):4755-4763. PubMed ID: 28053091
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  • 6. Hepatocyte spheroids as an alternative to single cells for transplantation after ex vivo gene therapy in mice and pig models.
    Nicolas CT, Hickey RD, Allen KL, Du Z, Guthman RM, Kaiser RA, Amiot B, Bansal A, Pandey MK, Suksanpaisan L, DeGrado TR, Nyberg SL, Lillegard JB.
    Surgery; 2018 Sep 17; 164(3):473-481. PubMed ID: 29884476
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  • 7. Ex vivo hepatic gene therapy of a mouse model of Hereditary Tyrosinemia Type I.
    Overturf K, Al-Dhalimy M, Manning K, Ou CN, Finegold M, Grompe M.
    Hum Gene Ther; 1998 Feb 10; 9(3):295-304. PubMed ID: 9508047
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  • 8. Kidneys of mice with hereditary tyrosinemia type I are extremely sensitive to cytotoxicity.
    Jacobs SM, van Beurden DH, Klomp LW, Berger R, van den Berg IE.
    Pediatr Res; 2006 Mar 10; 59(3):365-70. PubMed ID: 16492973
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  • 10. In vivo lentiviral vector gene therapy to cure hereditary tyrosinemia type 1 and prevent development of precancerous and cancerous lesions.
    Nicolas CT, VanLith CJ, Hickey RD, Du Z, Hillin LG, Guthman RM, Cao WJ, Haugo B, Lillegard A, Roy D, Bhagwate A, O'Brien D, Kocher JP, Kaiser RA, Russell SJ, Lillegard JB.
    Nat Commun; 2022 Aug 25; 13(1):5012. PubMed ID: 36008405
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  • 12. Messenger RNA as a source of transposase for sleeping beauty transposon-mediated correction of hereditary tyrosinemia type I.
    Wilber A, Wangensteen KJ, Chen Y, Zhuo L, Frandsen JL, Bell JB, Chen ZJ, Ekker SC, McIvor RS, Wang X.
    Mol Ther; 2007 Jul 25; 15(7):1280-7. PubMed ID: 17440442
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  • 18. Oxidative Stress, Glutathione Metabolism, and Liver Regeneration Pathways Are Activated in Hereditary Tyrosinemia Type 1 Mice upon Short-Term Nitisinone Discontinuation.
    Colemonts-Vroninks H, Neuckermans J, Marcelis L, Claes P, Branson S, Casimir G, Goyens P, Martens GA, Vanhaecke T, De Kock J.
    Genes (Basel); 2020 Dec 22; 12(1):. PubMed ID: 33375092
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  • 19. Fumarylacetoacetate hydrolase deficient pigs are a novel large animal model of metabolic liver disease.
    Hickey RD, Mao SA, Glorioso J, Lillegard JB, Fisher JE, Amiot B, Rinaldo P, Harding CO, Marler R, Finegold MJ, Grompe M, Nyberg SL.
    Stem Cell Res; 2014 Jul 22; 13(1):144-53. PubMed ID: 24879068
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