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Journal Abstract Search

307 related items for PubMed ID: 27466200

  • 1. Ataxin-1 regulates the cerebellar bioenergetics proteome through the GSK3β-mTOR pathway which is altered in Spinocerebellar ataxia type 1 (SCA1).
    Sánchez I, Balagué E, Matilla-Dueñas A.
    Hum Mol Genet; 2016 Sep 15; 25(18):4021-4040. PubMed ID: 27466200
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  • 3. Partial loss of ataxin-1 function contributes to transcriptional dysregulation in spinocerebellar ataxia type 1 pathogenesis.
    Crespo-Barreto J, Fryer JD, Shaw CA, Orr HT, Zoghbi HY.
    PLoS Genet; 2010 Jul 08; 6(7):e1001021. PubMed ID: 20628574
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  • 6. Lithium therapy improves neurological function and hippocampal dendritic arborization in a spinocerebellar ataxia type 1 mouse model.
    Watase K, Gatchel JR, Sun Y, Emamian E, Atkinson R, Richman R, Mizusawa H, Orr HT, Shaw C, Zoghbi HY.
    PLoS Med; 2007 May 08; 4(5):e182. PubMed ID: 17535104
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  • 10. Dual targeting of brain region-specific kinases potentiates neurological rescue in Spinocerebellar ataxia type 1.
    Lee WS, Lavery L, Rousseaux MWC, Rutledge EB, Jang Y, Wan YW, Wu SR, Kim W, Al-Ramahi I, Rath S, Adamski CJ, Bondar VV, Tewari A, Soleimani S, Mota S, Yalamanchili HK, Orr HT, Liu Z, Botas J, Zoghbi HY.
    EMBO J; 2021 Apr 01; 40(7):e106106. PubMed ID: 33709453
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  • 12. Indirect Negative Effect of Mutant Ataxin-1 on Short- and Long-Term Synaptic Plasticity in Mouse Models of Spinocerebellar Ataxia Type 1.
    Shuvaev AN, Belozor OS, Mozhei OI, Shuvaev AN, Fritsler YV, Khilazheva ED, Mosyagina AI, Hirai H, Teschemacher AG, Kasparov S.
    Cells; 2022 Jul 20; 11(14):. PubMed ID: 35883691
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  • 15. Reduction of protein kinase A-mediated phosphorylation of ATXN1-S776 in Purkinje cells delays onset of Ataxia in a SCA1 mouse model.
    Pérez Ortiz JM, Mollema N, Toker N, Adamski CJ, O'Callaghan B, Duvick L, Friedrich J, Walters MA, Strasser J, Hawkinson JE, Zoghbi HY, Henzler C, Orr HT, Lagalwar S.
    Neurobiol Dis; 2018 Aug 20; 116():93-105. PubMed ID: 29758256
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  • 16. Mutant ataxin1 disrupts cerebellar development in spinocerebellar ataxia type 1.
    Edamakanti CR, Do J, Didonna A, Martina M, Opal P.
    J Clin Invest; 2018 Jun 01; 128(6):2252-2265. PubMed ID: 29533923
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  • 18. Duplication of Atxn1l suppresses SCA1 neuropathology by decreasing incorporation of polyglutamine-expanded ataxin-1 into native complexes.
    Bowman AB, Lam YC, Jafar-Nejad P, Chen HK, Richman R, Samaco RC, Fryer JD, Kahle JJ, Orr HT, Zoghbi HY.
    Nat Genet; 2007 Mar 01; 39(3):373-9. PubMed ID: 17322884
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  • 19. Partial loss of Tip60 slows mid-stage neurodegeneration in a spinocerebellar ataxia type 1 (SCA1) mouse model.
    Gehrking KM, Andresen JM, Duvick L, Lough J, Zoghbi HY, Orr HT.
    Hum Mol Genet; 2011 Jun 01; 20(11):2204-12. PubMed ID: 21427130
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  • 20. Disruption of the ATXN1-CIC complex reveals the role of additional nuclear ATXN1 interactors in spinocerebellar ataxia type 1.
    Coffin SL, Durham MA, Nitschke L, Xhako E, Brown AM, Revelli JP, Villavicencio Gonzalez E, Lin T, Handler HP, Dai Y, Trostle AJ, Wan YW, Liu Z, Sillitoe RV, Orr HT, Zoghbi HY.
    Neuron; 2023 Feb 15; 111(4):481-492.e8. PubMed ID: 36577402
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