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195 related items for PubMed ID: 27477678

  • 1. Development of smart cell-free and cell-based assay systems for investigation of leukotriene C4 synthase activity and evaluation of inhibitors.
    Liening S, Scriba GK, Rummler S, Weinigel C, Kleinschmidt TK, Haeggström JZ, Werz O, Garscha U.
    Biochim Biophys Acta; 2016 Nov; 1861(11):1605-1613. PubMed ID: 27477678
    [Abstract] [Full Text] [Related]

  • 2. Pharmacological cross-reactivity between 5-lipoxygenase-activating protein, 5-lipoxygenase, and leukotriene C4 synthase.
    Gupta N, Nicholson DW, Ford-Hutchinson AW.
    Can J Physiol Pharmacol; 1997 Nov; 75(10-11):1212-9. PubMed ID: 9431445
    [Abstract] [Full Text] [Related]

  • 3. Increased leukotriene c4 synthesis accompanied enhanced leukotriene c4 synthase expression and activities of ischemia-reperfusion-injured liver in rats.
    Yang SL, Huang X, Chen HF, Xu D, Chen LJ, Kong Y, Lou YJ.
    J Surg Res; 2007 Jun 01; 140(1):36-44. PubMed ID: 17397868
    [Abstract] [Full Text] [Related]

  • 4. Human umbilical vein endothelial cells generate leukotriene C4 via microsomal glutathione S-transferase type 2 and express the CysLT(1) receptor.
    Sjöström M, Jakobsson PJ, Heimburger M, Palmblad J, Haeggström JZ.
    Eur J Biochem; 2001 May 01; 268(9):2578-86. PubMed ID: 11322876
    [Abstract] [Full Text] [Related]

  • 5. 12-Oxo-10-glutathionyl-5,8,14-eicosatrienoic acid (TOG10), a novel glutathione-containing eicosanoid generated via the 12-lipoxygenase pathway in human platelets.
    Liening S, Fischer J, Jagusch H, Pohnert G, Höcker O, Neusüß C, Werz O, Scriba GKE, Garscha U.
    Prostaglandins Other Lipid Mediat; 2021 Feb 01; 152():106480. PubMed ID: 33172790
    [Abstract] [Full Text] [Related]

  • 6. Crystal structure of a human membrane protein involved in cysteinyl leukotriene biosynthesis.
    Ago H, Kanaoka Y, Irikura D, Lam BK, Shimamura T, Austen KF, Miyano M.
    Nature; 2007 Aug 02; 448(7153):609-12. PubMed ID: 17632548
    [Abstract] [Full Text] [Related]

  • 7. Leukotriene C4 synthase: a pivotal enzyme in cellular biosynthesis of the cysteinyl leukotrienes.
    Lam BK, Austen KF.
    Prostaglandins Other Lipid Mediat; 2002 Aug 02; 68-69():511-20. PubMed ID: 12432940
    [Abstract] [Full Text] [Related]

  • 8. LTC4 synthase. Enzymology, biochemistry, and molecular characterization.
    Penrose JF.
    Clin Rev Allergy Immunol; 1999 Aug 02; 17(1-2):133-52. PubMed ID: 10436863
    [Abstract] [Full Text] [Related]

  • 9. Tandem Benzophenone Amino Pyridines, Potent and Selective Inhibitors of Human Leukotriene C4 Synthase.
    Kleinschmidt TK, Haraldsson M, Basavarajappa D, Lundeberg E, Thulasingam M, Ekoff M, Fauland A, Lehmann C, Kahnt AS, Lindbom L, Haeggström JZ.
    J Pharmacol Exp Ther; 2015 Oct 02; 355(1):108-16. PubMed ID: 26283693
    [Abstract] [Full Text] [Related]

  • 10. Human melanoma cells generate leukotrienes B4 and C4 from leukotriene A4.
    Okano-Mitani H, Ikai K, Imamura S.
    Arch Dermatol Res; 1997 May 02; 289(6):347-51. PubMed ID: 9209681
    [Abstract] [Full Text] [Related]

  • 11. Protein kinase C-dependent regulation of sulfidopeptide leukotriene biosynthesis and leukotriene C4 synthase in neutrophilic HL-60 cells.
    Kargman S, Ali A, Vaillancourt JP, Evans JF, Nicholson DW.
    Mol Pharmacol; 1994 May 02; 45(5):1043-9. PubMed ID: 8190095
    [Abstract] [Full Text] [Related]

  • 12. A leukotriene C4 synthase inhibitor with the backbone of 5-(5-methylene-4-oxo-4,5-dihydrothiazol-2-ylamino) isophthalic acid.
    Ago H, Okimoto N, Kanaoka Y, Morimoto G, Ukita Y, Saino H, Taiji M, Miyano M.
    J Biochem; 2013 May 02; 153(5):421-9. PubMed ID: 23378248
    [Abstract] [Full Text] [Related]

  • 13. Leukotriene C4 synthase is a novel PPARγ target gene, and leukotriene C4 and D4 activate adipogenesis through cysteinyl LT1 receptors in adipocytes.
    Fujimori K, Uno S, Kuroda K, Matsumoto C, Maehara T.
    Biochim Biophys Acta Mol Cell Res; 2022 Mar 02; 1869(3):119203. PubMed ID: 34968576
    [Abstract] [Full Text] [Related]

  • 14. Leukotriene A4 hydrolase and leukotriene C4 synthase activities in human chondrocytes: transcellular biosynthesis of Leukotrienes during granulocyte-chondrocyte interaction.
    Amat M, Díaz C, Vila L.
    Arthritis Rheum; 1998 Sep 02; 41(9):1645-51. PubMed ID: 9751098
    [Abstract] [Full Text] [Related]

  • 15. Enhanced expressions and activations of leukotriene C4 synthesis enzymes in D-galactosamine/lipopolysaccharide-induced rat fulminant hepatic failure model.
    Ma KF, Yang HY, Chen Z, Qi LY, Zhu DY, Lou YJ.
    World J Gastroenterol; 2008 May 07; 14(17):2748-56. PubMed ID: 18461660
    [Abstract] [Full Text] [Related]

  • 16. Inhibition of 5-lipoxygenase and leukotriene C4 synthase in human blood cells by thymoquinone.
    Mansour M, Tornhamre S.
    J Enzyme Inhib Med Chem; 2004 Oct 07; 19(5):431-6. PubMed ID: 15648658
    [Abstract] [Full Text] [Related]

  • 17. Expression cloning of a cDNA for human leukotriene C4 synthase, an integral membrane protein conjugating reduced glutathione to leukotriene A4.
    Lam BK, Penrose JF, Freeman GJ, Austen KF.
    Proc Natl Acad Sci U S A; 1994 Aug 02; 91(16):7663-7. PubMed ID: 8052639
    [Abstract] [Full Text] [Related]

  • 18. 14,15-Dehydroleukotriene A4: a specific substrate for leukotriene C4 synthase.
    Sala A, Garcia M, Zarini S, Rossi JC, Folco G, Durand T.
    Biochem J; 1997 Nov 15; 328 ( Pt 1)(Pt 1):225-9. PubMed ID: 9359857
    [Abstract] [Full Text] [Related]

  • 19. Characterization of leukotriene C4 synthetase in mouse peritoneal exudate cells.
    Abe M, Hugli TE.
    Biochim Biophys Acta; 1988 Apr 15; 959(3):386-98. PubMed ID: 2833315
    [Abstract] [Full Text] [Related]

  • 20. The biochemical, molecular, and genomic aspects of leukotriene C4 synthase.
    Penrose JF, Austen KF.
    Proc Assoc Am Physicians; 1999 Apr 15; 111(6):537-46. PubMed ID: 10591082
    [Abstract] [Full Text] [Related]

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