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123 related items for PubMed ID: 27483224

  • 1. Prenylated Chalcone 2 Acts as an Antimitotic Agent and Enhances the Chemosensitivity of Tumor Cells to Paclitaxel.
    Fonseca J, Marques S, Silva PM, Brandão P, Cidade H, Pinto MM, Bousbaa H.
    Molecules; 2016 Jul 29; 21(8):. PubMed ID: 27483224
    [Abstract] [Full Text] [Related]

  • 2. Chalcone derivatives targeting mitosis: synthesis, evaluation of antitumor activity and lipophilicity.
    Pinto P, Machado CM, Moreira J, Almeida JDP, Silva PMA, Henriques AC, Soares JX, Salvador JAR, Afonso C, Pinto M, Bousbaa H, Cidade H.
    Eur J Med Chem; 2019 Dec 15; 184():111752. PubMed ID: 31610374
    [Abstract] [Full Text] [Related]

  • 3. Evaluation of 2',4'-dihydroxy-3,4,5-trimethoxychalcone as antimitotic agent that induces mitotic catastrophe in MCF-7 breast cancer cells.
    Masawang K, Pedro M, Cidade H, Reis RM, Neves MP, Corrêa AG, Sudprasert W, Bousbaa H, Pinto MM.
    Toxicol Lett; 2014 Sep 02; 229(2):393-401. PubMed ID: 24968064
    [Abstract] [Full Text] [Related]

  • 4. Antagonizing the spindle assembly checkpoint silencing enhances paclitaxel and Navitoclax-mediated apoptosis with distinct mechanistic.
    Henriques AC, Silva PMA, Sarmento B, Bousbaa H.
    Sci Rep; 2021 Feb 18; 11(1):4139. PubMed ID: 33603057
    [Abstract] [Full Text] [Related]

  • 5. Enhanced cytotoxicity of prenylated chalcone against tumour cells via disruption of the p53-MDM2 interaction.
    Leão M, Soares J, Gomes S, Raimundo L, Ramos H, Bessa C, Queiroz G, Domingos S, Pinto M, Inga A, Cidade H, Saraiva L.
    Life Sci; 2015 Dec 01; 142():60-5. PubMed ID: 26475964
    [Abstract] [Full Text] [Related]

  • 6. K858, a novel inhibitor of mitotic kinesin Eg5 and antitumor agent, induces cell death in cancer cells.
    Nakai R, Iida S, Takahashi T, Tsujita T, Okamoto S, Takada C, Akasaka K, Ichikawa S, Ishida H, Kusaka H, Akinaga S, Murakata C, Honda S, Nitta M, Saya H, Yamashita Y.
    Cancer Res; 2009 May 01; 69(9):3901-9. PubMed ID: 19351824
    [Abstract] [Full Text] [Related]

  • 7. Relationship of mitotic arrest and apoptosis to antitumor effect of paclitaxel.
    Milross CG, Mason KA, Hunter NR, Chung WK, Peters LJ, Milas L.
    J Natl Cancer Inst; 1996 Sep 18; 88(18):1308-14. PubMed ID: 8797771
    [Abstract] [Full Text] [Related]

  • 8. Involvement of p21 in mitotic exit after paclitaxel treatment in MCF-7 breast adenocarcinoma cell line.
    Barboule N, Chadebech P, Baldin V, Vidal S, Valette A.
    Oncogene; 1997 Dec 04; 15(23):2867-75. PubMed ID: 9419978
    [Abstract] [Full Text] [Related]

  • 9. Post-slippage multinucleation renders cytotoxic variation in anti-mitotic drugs that target the microtubules or mitotic spindle.
    Zhu Y, Zhou Y, Shi J.
    Cell Cycle; 2014 Dec 04; 13(11):1756-64. PubMed ID: 24694730
    [Abstract] [Full Text] [Related]

  • 10. Polo-like kinase 1 inhibitor BI2536 causes mitotic catastrophe following activation of the spindle assembly checkpoint in non-small cell lung cancer cells.
    Choi M, Kim W, Cheon MG, Lee CW, Kim JE.
    Cancer Lett; 2015 Feb 28; 357(2):591-601. PubMed ID: 25524551
    [Abstract] [Full Text] [Related]

  • 11. Targeting the MDM2-p53 protein-protein interaction with prenylchalcones: Synthesis of a small library and evaluation of potential antitumor activity.
    Brandão P, Loureiro JB, Carvalho S, Hamadou MH, Cravo S, Moreira J, Pereira D, Palmeira A, Pinto M, Saraiva L, Cidade H.
    Eur J Med Chem; 2018 Aug 05; 156():711-721. PubMed ID: 30041135
    [Abstract] [Full Text] [Related]

  • 12. Paclitaxel inhibits progression of mitotic cells to G1 phase by interference with spindle formation without affecting other microtubule functions during anaphase and telephase.
    Long BH, Fairchild CR.
    Cancer Res; 1994 Aug 15; 54(16):4355-61. PubMed ID: 7913875
    [Abstract] [Full Text] [Related]

  • 13. A Pyranoxanthone as a Potent Antimitotic and Sensitizer of Cancer Cells to Low Doses of Paclitaxel.
    França F, Silva PMA, Soares JX, Henriques AC, Loureiro DRP, Azevedo CMG, Afonso CMM, Bousbaa H.
    Molecules; 2020 Dec 10; 25(24):. PubMed ID: 33322077
    [Abstract] [Full Text] [Related]

  • 14. Pharmacological and small interference RNA-mediated inhibition of breast cancer-associated fatty acid synthase (oncogenic antigen-519) synergistically enhances Taxol (paclitaxel)-induced cytotoxicity.
    Menendez JA, Vellon L, Colomer R, Lupu R.
    Int J Cancer; 2005 May 20; 115(1):19-35. PubMed ID: 15657900
    [Abstract] [Full Text] [Related]

  • 15. Tumor-Associated Macrophages Suppress the Cytotoxic Activity of Antimitotic Agents.
    Olson OC, Kim H, Quail DF, Foley EA, Joyce JA.
    Cell Rep; 2017 Apr 04; 19(1):101-113. PubMed ID: 28380350
    [Abstract] [Full Text] [Related]

  • 16. BP-M345 as a Basis for the Discovery of New Diarylpentanoids with Promising Antimitotic Activity.
    Moreira J, Silva PMA, Castro E, Saraiva L, Pinto M, Bousbaa H, Cidade H.
    Int J Mol Sci; 2024 Jan 30; 25(3):. PubMed ID: 38338967
    [Abstract] [Full Text] [Related]

  • 17. Cytotoxicity of paclitaxel in breast cancer is due to chromosome missegregation on multipolar spindles.
    Zasadil LM, Andersen KA, Yeum D, Rocque GB, Wilke LG, Tevaarwerk AJ, Raines RT, Burkard ME, Weaver BA.
    Sci Transl Med; 2014 Mar 26; 6(229):229ra43. PubMed ID: 24670687
    [Abstract] [Full Text] [Related]

  • 18. PKC inhibitor Go6976 induces mitosis and enhances doxorubicin-paclitaxel cytotoxicity in urinary bladder carcinoma cells.
    Aaltonen V, Koivunen J, Laato M, Peltonen J.
    Cancer Lett; 2007 Aug 08; 253(1):97-107. PubMed ID: 17320279
    [Abstract] [Full Text] [Related]

  • 19. Association between mitotic spindle checkpoint impairment and susceptibility to the induction of apoptosis by anti-microtubule agents in human lung cancers.
    Masuda A, Maeno K, Nakagawa T, Saito H, Takahashi T.
    Am J Pathol; 2003 Sep 08; 163(3):1109-16. PubMed ID: 12937152
    [Abstract] [Full Text] [Related]

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