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Journal Abstract Search

196 related items for PubMed ID: 27530964

  • 1. Development of an in vitro high content imaging assay for quantitative assessment of CAR-dependent mouse, rat, and human primary hepatocyte proliferation.
    Soldatow V, Peffer RC, Trask OJ, Cowie DE, Andersen ME, LeCluyse E, Deisenroth C.
    Toxicol In Vitro; 2016 Oct; 36():224-237. PubMed ID: 27530964
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  • 2. Regulation of gender-dependent CYP2A expression in pigs: involvement of androgens and CAR.
    Gillberg M, Skaanild MT, Friis C.
    Basic Clin Pharmacol Toxicol; 2006 May; 98(5):480-7. PubMed ID: 16635107
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  • 3. Stilbene compound trans-3,4,5,4´-tetramethoxystilbene, a potential anticancer drug, regulates constitutive androstane receptor (Car) target genes, but does not possess proliferative activity in mouse liver.
    Dusek J, Skoda J, Holas O, Horvatova A, Smutny T, Linhartova L, Hirsova P, Kucera O, Micuda S, Braeuning A, Pavek P.
    Toxicol Lett; 2019 Oct 01; 313():1-10. PubMed ID: 31170421
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  • 5. Human hepatocytes support the hypertrophic but not the hyperplastic response to the murine nongenotoxic hepatocarcinogen sodium phenobarbital in an in vivo study using a chimeric mouse with humanized liver.
    Yamada T, Okuda Y, Kushida M, Sumida K, Takeuchi H, Nagahori H, Fukuda T, Lake BG, Cohen SM, Kawamura S.
    Toxicol Sci; 2014 Nov 01; 142(1):137-57. PubMed ID: 25145657
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  • 6. Mode of action analysis for fluxapyroxad-induced rat liver tumour formation: evidence for activation of the constitutive androstane receptor and assessment of human relevance.
    Goettel M, Werner C, Honarvar N, Gröters S, Fegert I, Haines C, Chatham LR, Vardy A, Lake BG.
    Toxicology; 2024 Jun 01; 505():153828. PubMed ID: 38740169
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  • 8. Comparative studies on the effects of sodium phenobarbital and two other constitutive androstane receptor (CAR) activators on induction of cytochrome P450 enzymes and replicative DNA synthesis in cultured hepatocytes from wild type and CAR knockout rats.
    Goettel M, Fegert I, Honarvar N, Vardy A, Haines C, Chatham LR, Lake BG.
    Toxicology; 2020 Mar 30; 433-434():152394. PubMed ID: 32027962
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  • 9. Comparison of the effects of sodium phenobarbital in wild type and humanized constitutive androstane receptor (CAR)/pregnane X receptor (PXR) mice and in cultured mouse, rat and human hepatocytes.
    Haines C, Elcombe BM, Chatham LR, Vardy A, Higgins LG, Elcombe CR, Lake BG.
    Toxicology; 2018 Mar 01; 396-397():23-32. PubMed ID: 29425889
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  • 11. Epidermal Growth Factor Represses Constitutive Androstane Receptor Expression in Primary Human Hepatocytes and Favors Regulation by Pregnane X Receptor.
    de Boussac H, Gondeau C, Briolotti P, Duret C, Treindl F, Römer M, Fabre JM, Herrero A, Ramos J, Maurel P, Templin M, Gerbal-Chaloin S, Daujat-Chavanieu M.
    Drug Metab Dispos; 2018 Mar 01; 46(3):223-236. PubMed ID: 29269410
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  • 13. Estrogen activation of the nuclear orphan receptor CAR (constitutive active receptor) in induction of the mouse Cyp2b10 gene.
    Kawamoto T, Kakizaki S, Yoshinari K, Negishi M.
    Mol Endocrinol; 2000 Nov 01; 14(11):1897-905. PubMed ID: 11075820
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  • 19. Role of YAP Activation in Nuclear Receptor CAR-Mediated Proliferation of Mouse Hepatocytes.
    Abe T, Amaike Y, Shizu R, Takahashi M, Kano M, Hosaka T, Sasaki T, Kodama S, Matsuzawa A, Yoshinari K.
    Toxicol Sci; 2018 Oct 01; 165(2):408-419. PubMed ID: 29893953
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  • 20. Mouse liver effects of cyproconazole, a triazole fungicide: role of the constitutive androstane receptor.
    Peffer RC, Moggs JG, Pastoor T, Currie RA, Wright J, Milburn G, Waechter F, Rusyn I.
    Toxicol Sci; 2007 Sep 01; 99(1):315-25. PubMed ID: 17557908
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