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Journal Abstract Search

191 related items for PubMed ID: 27550925

  • 1. Original Research: Featured Article: Imatinib mesylate (Gleevec) inhibits Notch and c-Myc signaling: Five-day treatment permanently rescues mammary development.
    Callahan R, Chestnut BA, Raafat A.
    Exp Biol Med (Maywood); 2017 Jan; 242(1):53-67. PubMed ID: 27550925
    [Abstract] [Full Text] [Related]

  • 2. Kit and PDGFR-alpha activities are necessary for Notch4/Int3-induced tumorigenesis.
    Raafat A, Zoltan-Jones A, Strizzi L, Bargo S, Kimura K, Salomon D, Callahan R.
    Oncogene; 2007 Feb 01; 26(5):662-72. PubMed ID: 16878155
    [Abstract] [Full Text] [Related]

  • 3. Rbpj conditional knockout reveals distinct functions of Notch4/Int3 in mammary gland development and tumorigenesis.
    Raafat A, Lawson S, Bargo S, Klauzinska M, Strizzi L, Goldhar AS, Buono K, Salomon D, Vonderhaar BK, Callahan R.
    Oncogene; 2009 Jan 15; 28(2):219-30. PubMed ID: 18836481
    [Abstract] [Full Text] [Related]

  • 4. Mammary development and tumorigenesis in mice expressing a truncated human Notch4/Int3 intracellular domain (h-Int3sh).
    Raafat A, Bargo S, Anver MR, Callahan R.
    Oncogene; 2004 Dec 16; 23(58):9401-7. PubMed ID: 15531924
    [Abstract] [Full Text] [Related]

  • 5. The ANK repeats of Notch-4/Int3 activate NF-κB canonical pathway in the absence of Rbpj and causes mammary tumorigenesis.
    Raafat A, Bargo S, McCurdy D, Callahan R.
    Sci Rep; 2017 Oct 20; 7(1):13690. PubMed ID: 29057904
    [Abstract] [Full Text] [Related]

  • 6. Expression of a truncated Int3 gene in developing secretory mammary epithelium specifically retards lobular differentiation resulting in tumorigenesis.
    Gallahan D, Jhappan C, Robinson G, Hennighausen L, Sharp R, Kordon E, Callahan R, Merlino G, Smith GH.
    Cancer Res; 1996 Apr 15; 56(8):1775-85. PubMed ID: 8620493
    [Abstract] [Full Text] [Related]

  • 7. Notch-induced mammary tumorigenesis does not involve the lobule-limited epithelial progenitor.
    Bruno RD, Boulanger CA, Smith GH.
    Oncogene; 2012 Jan 05; 31(1):60-7. PubMed ID: 21666720
    [Abstract] [Full Text] [Related]

  • 8. Constitutive expression of a truncated INT3 gene in mouse mammary epithelium impairs differentiation and functional development.
    Smith GH, Gallahan D, Diella F, Jhappan C, Merlino G, Callahan R.
    Cell Growth Differ; 1995 May 05; 6(5):563-77. PubMed ID: 7544153
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of mammary gland involution is associated with transforming growth factor alpha but not c-myc-induced tumorigenesis in transgenic mice.
    Sandgren EP, Schroeder JA, Qui TH, Palmiter RD, Brinster RL, Lee DC.
    Cancer Res; 1995 Sep 01; 55(17):3915-27. PubMed ID: 7641211
    [Abstract] [Full Text] [Related]

  • 10. The mouse mammary tumor associated gene INT3 is a unique member of the NOTCH gene family (NOTCH4).
    Gallahan D, Callahan R.
    Oncogene; 1997 Apr 24; 14(16):1883-90. PubMed ID: 9150355
    [Abstract] [Full Text] [Related]

  • 11. Functional mammary gland development and oncogene-induced tumor formation are not affected by the absence of the retinoblastoma gene.
    Robinson GW, Wagner KU, Hennighausen L.
    Oncogene; 2001 Oct 25; 20(48):7115-9. PubMed ID: 11704837
    [Abstract] [Full Text] [Related]

  • 12. Aberrant development of mammary glands, but precocious expression of beta-casein in transgenic females ubiquitously expressing whey acidic protein transgene.
    Iwamori T, Oosawa M, Nukumi N, Kano K, Sudo K, Naito K, Tojo H.
    J Reprod Dev; 2005 Oct 25; 51(5):579-92. PubMed ID: 16195641
    [Abstract] [Full Text] [Related]

  • 13. Mnt-deficient mammary glands exhibit impaired involution and tumors with characteristics of myc overexpression.
    Toyo-oka K, Bowen TJ, Hirotsune S, Li Z, Jain S, Ota S, Escoubet-Lozach L, Garcia-Bassets I, Lozach J, Rosenfeld MG, Glass CK, Eisenman R, Ren B, Hurlin P, Wynshaw-Boris A.
    Cancer Res; 2006 Jun 01; 66(11):5565-73. PubMed ID: 16740691
    [Abstract] [Full Text] [Related]

  • 14. Intracisternal type A particle-mediated activation of the Notch4/int3 gene in a mouse mammary tumor: generation of truncated Notch4/int3 mRNAs by retroviral splicing events.
    Lee JS, Haruna T, Ishimoto A, Honjo T, Yanagawa S.
    J Virol; 1999 Jun 01; 73(6):5166-71. PubMed ID: 10233982
    [Abstract] [Full Text] [Related]

  • 15. Understanding mammary gland development through the imbalanced expression of growth regulators.
    Robinson GW, Smith GH, Gallahan D, Zimmer A, Furth PA, Hennighausen L.
    Dev Dyn; 1996 Jun 01; 206(2):159-68. PubMed ID: 8725283
    [Abstract] [Full Text] [Related]

  • 16. Transforming acidic coiled-coil protein-3 (Tacc3) acts as a negative regulator of Notch signaling through binding to CDC10/Ankyrin repeats.
    Bargo S, Raafat A, McCurdy D, Amirjazil I, Shu Y, Traicoff J, Plant J, Vonderhaar BK, Callahan R.
    Biochem Biophys Res Commun; 2010 Oct 01; 400(4):606-12. PubMed ID: 20804727
    [Abstract] [Full Text] [Related]

  • 17. Imatinib Spares cKit-Expressing Prostate Neuroendocrine Tumors, whereas Kills Seminal Vesicle Epithelial-Stromal Tumors by Targeting PDGFR-β.
    Jachetti E, Rigoni A, Bongiovanni L, Arioli I, Botti L, Parenza M, Cancila V, Chiodoni C, Festinese F, Bellone M, Tardanico R, Tripodo C, Colombo MP.
    Mol Cancer Ther; 2017 Feb 01; 16(2):365-375. PubMed ID: 27980106
    [Abstract] [Full Text] [Related]

  • 18. Synergistic interaction of transforming growth factor alpha and c-myc in mouse mammary and salivary gland tumorigenesis.
    Amundadottir LT, Johnson MD, Merlino G, Smith GH, Dickson RB.
    Cell Growth Differ; 1995 Jun 01; 6(6):737-48. PubMed ID: 7669729
    [Abstract] [Full Text] [Related]

  • 19. Acceleration of tumor growth and peri-tumoral blood clotting by imatinib mesylate (Gleevec).
    Samoszuk M, Corwin MA.
    Int J Cancer; 2003 Sep 20; 106(5):647-52. PubMed ID: 12866022
    [Abstract] [Full Text] [Related]

  • 20. Targeted c-myc gene expression in mammary glands of transgenic mice induces mammary tumours with constitutive milk protein gene transcription.
    Schoenenberger CA, Andres AC, Groner B, van der Valk M, LeMeur M, Gerlinger P.
    EMBO J; 1988 Jan 20; 7(1):169-75. PubMed ID: 2834201
    [Abstract] [Full Text] [Related]

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