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665 related items for PubMed ID: 27551074

  • 1. Endogenous macrophage migration inhibitory factor reduces the accumulation and toxicity of misfolded SOD1 in a mouse model of ALS.
    Leyton-Jaimes MF, Benaim C, Abu-Hamad S, Kahn J, Guetta A, Bucala R, Israelson A.
    Proc Natl Acad Sci U S A; 2016 Sep 06; 113(36):10198-203. PubMed ID: 27551074
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  • 2. AAV2/9-mediated overexpression of MIF inhibits SOD1 misfolding, delays disease onset, and extends survival in mouse models of ALS.
    Leyton-Jaimes MF, Kahn J, Israelson A.
    Proc Natl Acad Sci U S A; 2019 Jul 16; 116(29):14755-14760. PubMed ID: 31262807
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  • 3. Targeting low levels of MIF expression as a potential therapeutic strategy for ALS.
    Alfahel L, Gschwendtberger T, Kozareva V, Dumas L, Gibbs R, Kertser A, Baruch K, Zaccai S, Kahn J, Thau-Habermann N, Eggenschwiler R, Sterneckert J, Hermann A, Sundararaman N, Vaibhav V, Van Eyk JE, Rafuse VF, Fraenkel E, Cantz T, Petri S, Israelson A.
    Cell Rep Med; 2024 May 21; 5(5):101546. PubMed ID: 38703766
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  • 4. MIF inhibits the formation and toxicity of misfolded SOD1 amyloid aggregates: implications for familial ALS.
    Shvil N, Banerjee V, Zoltsman G, Shani T, Kahn J, Abu-Hamad S, Papo N, Engel S, Bernhagen J, Israelson A.
    Cell Death Dis; 2018 Jan 25; 9(2):107. PubMed ID: 29371591
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  • 5. Macrophage migration inhibitory factor as a chaperone inhibiting accumulation of misfolded SOD1.
    Israelson A, Ditsworth D, Sun S, Song S, Liang J, Hruska-Plochan M, McAlonis-Downes M, Abu-Hamad S, Zoltsman G, Shani T, Maldonado M, Bui A, Navarro M, Zhou H, Marsala M, Kaspar BK, Da Cruz S, Cleveland DW.
    Neuron; 2015 Apr 08; 86(1):218-32. PubMed ID: 25801706
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  • 6. MIF homolog d-dopachrome tautomerase (D-DT/MIF-2) does not inhibit accumulation and toxicity of misfolded SOD1.
    Alaskarov A, Barel S, Bakavayev S, Kahn J, Israelson A.
    Sci Rep; 2022 Jun 10; 12(1):9570. PubMed ID: 35688953
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  • 7. Distinct conformers of transmissible misfolded SOD1 distinguish human SOD1-FALS from other forms of familial and sporadic ALS.
    Ayers JI, Diamond J, Sari A, Fromholt S, Galaleldeen A, Ostrow LW, Glass JD, Hart PJ, Borchelt DR.
    Acta Neuropathol; 2016 Dec 10; 132(6):827-840. PubMed ID: 27704280
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  • 8. ERp57 is protective against mutant SOD1-induced cellular pathology in amyotrophic lateral sclerosis.
    Parakh S, Jagaraj CJ, Vidal M, Ragagnin AMG, Perri ER, Konopka A, Toth RP, Galper J, Blair IP, Thomas CJ, Walker AK, Yang S, Spencer DM, Atkin JD.
    Hum Mol Genet; 2018 Apr 15; 27(8):1311-1331. PubMed ID: 29409023
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  • 16. Prion-like propagation of mutant SOD1 misfolding and motor neuron disease spread along neuroanatomical pathways.
    Ayers JI, Fromholt SE, O'Neal VM, Diamond JH, Borchelt DR.
    Acta Neuropathol; 2016 Jan 15; 131(1):103-14. PubMed ID: 26650262
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  • 17. A copper-deficient form of mutant Cu/Zn-superoxide dismutase as an early pathological species in amyotrophic lateral sclerosis.
    Tokuda E, Nomura T, Ohara S, Watanabe S, Yamanaka K, Morisaki Y, Misawa H, Furukawa Y.
    Biochim Biophys Acta Mol Basis Dis; 2018 Jun 15; 1864(6 Pt A):2119-2130. PubMed ID: 29551730
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