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Journal Abstract Search

695 related items for PubMed ID: 27582570

  • 1. The relevance of PTEN-AKT in relation to NOTCH1-directed treatment strategies in T-cell acute lymphoblastic leukemia.
    Mendes RD, Canté-Barrett K, Pieters R, Meijerink JP.
    Haematologica; 2016 Sep; 101(9):1010-7. PubMed ID: 27582570
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  • 2. New insights into Notch1 regulation of the PI3K-AKT-mTOR1 signaling axis: targeted therapy of γ-secretase inhibitor resistant T-cell acute lymphoblastic leukemia.
    Hales EC, Taub JW, Matherly LH.
    Cell Signal; 2014 Jan; 26(1):149-61. PubMed ID: 24140475
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  • 3. Notch1 receptor regulates AKT protein activation loop (Thr308) dephosphorylation through modulation of the PP2A phosphatase in phosphatase and tensin homolog (PTEN)-null T-cell acute lymphoblastic leukemia cells.
    Hales EC, Orr SM, Larson Gedman A, Taub JW, Matherly LH.
    J Biol Chem; 2013 Aug 02; 288(31):22836-48. PubMed ID: 23788636
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  • 4. Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia.
    Palomero T, Sulis ML, Cortina M, Real PJ, Barnes K, Ciofani M, Caparros E, Buteau J, Brown K, Perkins SL, Bhagat G, Agarwal AM, Basso G, Castillo M, Nagase S, Cordon-Cardo C, Parsons R, Zúñiga-Pflücker JC, Dominguez M, Ferrando AA.
    Nat Med; 2007 Oct 02; 13(10):1203-10. PubMed ID: 17873882
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  • 10. Recent advances on NOTCH signaling in T-ALL.
    Tzoneva G, Ferrando AA.
    Curr Top Microbiol Immunol; 2012 Oct 02; 360():163-82. PubMed ID: 22673746
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  • 12. The role of the PTEN/AKT Pathway in NOTCH1-induced leukemia.
    Palomero T, Dominguez M, Ferrando AA.
    Cell Cycle; 2008 Apr 15; 7(8):965-70. PubMed ID: 18414037
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  • 13. Marsdenia tenacissimae extraction (MTE) inhibits the proliferation and induces the apoptosis of human acute T cell leukemia cells through inactivating PI3K/AKT/mTOR signaling pathway via PTEN enhancement.
    Wang Y, Chen B, Wang Z, Zhang W, Hao K, Chen Y, Li K, Wang T, Xie Y, Huang Z, Tong X.
    Oncotarget; 2016 Dec 13; 7(50):82851-82863. PubMed ID: 27756877
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  • 14. Targeting the translational apparatus to improve leukemia therapy: roles of the PI3K/PTEN/Akt/mTOR pathway.
    Martelli AM, Evangelisti C, Chappell W, Abrams SL, Bäsecke J, Stivala F, Donia M, Fagone P, Nicoletti F, Libra M, Ruvolo V, Ruvolo P, Kempf CR, Steelman LS, McCubrey JA.
    Leukemia; 2011 Jul 13; 25(7):1064-79. PubMed ID: 21436840
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  • 15. Murine Pten(-/-) T-ALL requires non-redundant PI3K/mTOR and DLL4/Notch1 signals for maintenance and γc/TCR signals for thymic exit.
    Hagenbeek TJ, Wu X, Choy L, Sanchez-Irizarry C, Seshagiri S, Stinson J, Siebel CW, Spits H.
    Cancer Lett; 2014 May 01; 346(2):237-48. PubMed ID: 24384093
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  • 16. Miltefosine suppression of Pten null T-ALL leukemia via β-catenin degradation through inhibition of pT308-Akt and TGFβ1/Smad3.
    Zhang Y, Lee S, Xu W.
    Biochem Biophys Res Commun; 2020 Apr 16; 524(4):1018-1024. PubMed ID: 32063363
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  • 17. Inhibition of NOTCH signaling by gamma secretase inhibitor engages the RB pathway and elicits cell cycle exit in T-cell acute lymphoblastic leukemia cells.
    Rao SS, O'Neil J, Liberator CD, Hardwick JS, Dai X, Zhang T, Tyminski E, Yuan J, Kohl NE, Richon VM, Van der Ploeg LH, Carroll PM, Draetta GF, Look AT, Strack PR, Winter CG.
    Cancer Res; 2009 Apr 01; 69(7):3060-8. PubMed ID: 19318552
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  • 18. Loss of oncogenic Notch1 with resistance to a PI3K inhibitor in T-cell leukaemia.
    Dail M, Wong J, Lawrence J, O'Connor D, Nakitandwe J, Chen SC, Xu J, Lee LB, Akagi K, Li Q, Aster JC, Pear WS, Downing JR, Sampath D, Shannon K.
    Nature; 2014 Sep 25; 513(7519):512-6. PubMed ID: 25043004
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  • 19. The impact of NOTCH1, FBW7 and PTEN mutations on prognosis and downstream signaling in pediatric T-cell acute lymphoblastic leukemia: a report from the Children's Oncology Group.
    Larson Gedman A, Chen Q, Kugel Desmoulin S, Ge Y, LaFiura K, Haska CL, Cherian C, Devidas M, Linda SB, Taub JW, Matherly LH.
    Leukemia; 2009 Aug 25; 23(8):1417-25. PubMed ID: 19340001
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