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2511 related items for PubMed ID: 27599716

  • 1. Aβ-Induced Drp1 phosphorylation through Akt activation promotes excessive mitochondrial fission leading to neuronal apoptosis.
    Kim DI, Lee KH, Gabr AA, Choi GE, Kim JS, Ko SH, Han HJ.
    Biochim Biophys Acta; 2016 Nov; 1863(11):2820-2834. PubMed ID: 27599716
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  • 3. Polyphyllin I induces mitophagic and apoptotic cell death in human breast cancer cells by increasing mitochondrial PINK1 levels.
    Li GB, Fu RQ, Shen HM, Zhou J, Hu XY, Liu YX, Li YN, Zhang HW, Liu X, Zhang YH, Huang C, Zhang R, Gao N.
    Oncotarget; 2017 Feb 07; 8(6):10359-10374. PubMed ID: 28060722
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  • 5. Ethanol-activated CaMKII signaling induces neuronal apoptosis through Drp1-mediated excessive mitochondrial fission and JNK1-dependent NLRP3 inflammasome activation.
    Lim JR, Lee HJ, Jung YH, Kim JS, Chae CW, Kim SY, Han HJ.
    Cell Commun Signal; 2020 Aug 12; 18(1):123. PubMed ID: 32787872
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  • 6. Iron overload promotes mitochondrial fragmentation in mesenchymal stromal cells from myelodysplastic syndrome patients through activation of the AMPK/MFF/Drp1 pathway.
    Zheng Q, Zhao Y, Guo J, Zhao S, Fei C, Xiao C, Wu D, Wu L, Li X, Chang C.
    Cell Death Dis; 2018 May 01; 9(5):515. PubMed ID: 29725013
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  • 7. Inhibition of ERK-DLP1 signaling and mitochondrial division alleviates mitochondrial dysfunction in Alzheimer's disease cybrid cell.
    Gan X, Huang S, Wu L, Wang Y, Hu G, Li G, Zhang H, Yu H, Swerdlow RH, Chen JX, Yan SS.
    Biochim Biophys Acta; 2014 Feb 01; 1842(2):220-31. PubMed ID: 24252614
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  • 8. Inhibition of Drp1 protects against senecionine-induced mitochondria-mediated apoptosis in primary hepatocytes and in mice.
    Yang X, Wang H, Ni HM, Xiong A, Wang Z, Sesaki H, Ding WX, Yang L.
    Redox Biol; 2017 Aug 01; 12():264-273. PubMed ID: 28282614
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  • 9. Dynamin-related protein 1 mediates mitochondria-dependent apoptosis in chlorpyrifos-treated SH-SY5Y cells.
    Park JH, Ko J, Hwang J, Koh HC.
    Neurotoxicology; 2015 Dec 01; 51():145-57. PubMed ID: 26598294
    [Abstract] [Full Text] [Related]

  • 10. Differentiation inducing factor 3 mediates its anti-leukemic effect through ROS-dependent DRP1-mediated mitochondrial fission and induction of caspase-independent cell death.
    Dubois A, Ginet C, Furstoss N, Belaid A, Hamouda MA, El Manaa W, Cluzeau T, Marchetti S, Ricci JE, Jacquel A, Luciano F, Driowya M, Benhida R, Auberger P, Robert G.
    Oncotarget; 2016 May 03; 7(18):26120-36. PubMed ID: 27027430
    [Abstract] [Full Text] [Related]

  • 11. Hydrogen sulfide inhibits mitochondrial fission in neuroblastoma N2a cells through the Drp1/ERK1/2 signaling pathway.
    Qiao P, Zhao F, Liu M, Gao D, Zhang H, Yan Y.
    Mol Med Rep; 2017 Jul 03; 16(1):971-977. PubMed ID: 28560384
    [Abstract] [Full Text] [Related]

  • 12. Aqua-soluble DDQ reduces the levels of Drp1 and Aβ and inhibits abnormal interactions between Aβ and Drp1 and protects Alzheimer's disease neurons from Aβ- and Drp1-induced mitochondrial and synaptic toxicities.
    Kuruva CS, Manczak M, Yin X, Ogunmokun G, Reddy AP, Reddy PH.
    Hum Mol Genet; 2017 Sep 01; 26(17):3375-3395. PubMed ID: 28854701
    [Abstract] [Full Text] [Related]

  • 13. Pharmacological Activation of AMPK Prevents Drp1-mediated Mitochondrial Fission and Alleviates Hepatic Steatosis In vitro.
    Du J, Wang T, Xiao C, Dong Y, Zhou S, Zhu Y.
    Curr Mol Med; 2024 Sep 01; 24(12):1506-1517. PubMed ID: 38310549
    [Abstract] [Full Text] [Related]

  • 14. ROS-mediated activation and mitochondrial translocation of CaMKII contributes to Drp1-dependent mitochondrial fission and apoptosis in triple-negative breast cancer cells by isorhamnetin and chloroquine.
    Hu J, Zhang Y, Jiang X, Zhang H, Gao Z, Li Y, Fu R, Li L, Li J, Cui H, Gao N.
    J Exp Clin Cancer Res; 2019 May 28; 38(1):225. PubMed ID: 31138329
    [Abstract] [Full Text] [Related]

  • 15. Hyperoside protects primary rat cortical neurons from neurotoxicity induced by amyloid β-protein via the PI3K/Akt/Bad/Bcl(XL)-regulated mitochondrial apoptotic pathway.
    Zeng KW, Wang XM, Ko H, Kwon HC, Cha JW, Yang HO.
    Eur J Pharmacol; 2011 Dec 15; 672(1-3):45-55. PubMed ID: 21978835
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  • 16. Isoliquiritigenin attenuates glutamate-induced mitochondrial fission via calcineurin-mediated Drp1 dephosphorylation in HT22 hippocampal neuron cells.
    Lee DG, Min JS, Lee HS, Lee DS.
    Neurotoxicology; 2018 Sep 15; 68():133-141. PubMed ID: 30048666
    [Abstract] [Full Text] [Related]

  • 17. Dynamin-related protein 1-mediated mitochondrial fission contributes to IR-783-induced apoptosis in human breast cancer cells.
    Tang Q, Liu W, Zhang Q, Huang J, Hu C, Liu Y, Wang Q, Zhou M, Lai W, Sheng F, Li G, Zhang R.
    J Cell Mol Med; 2018 Sep 15; 22(9):4474-4485. PubMed ID: 29993201
    [Abstract] [Full Text] [Related]

  • 18. Retinol binding protein 4 induces mitochondrial dysfunction and vascular oxidative damage.
    Wang J, Chen H, Liu Y, Zhou W, Sun R, Xia M.
    Atherosclerosis; 2015 Jun 15; 240(2):335-44. PubMed ID: 25875385
    [Abstract] [Full Text] [Related]

  • 19. Mitochondrial division inhibitor 1 reduces dynamin-related protein 1 and mitochondrial fission activity.
    Manczak M, Kandimalla R, Yin X, Reddy PH.
    Hum Mol Genet; 2019 Jan 15; 28(2):177-199. PubMed ID: 30239719
    [Abstract] [Full Text] [Related]

  • 20. Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage.
    Manczak M, Reddy PH.
    Hum Mol Genet; 2012 Jun 01; 21(11):2538-47. PubMed ID: 22367970
    [Abstract] [Full Text] [Related]

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