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Journal Abstract Search

362 related items for PubMed ID: 27614009

  • 21. The impact of ABCB1 and CES1 polymorphisms on dabigatran pharmacokinetics and pharmacodynamics in patients with atrial fibrillation.
    Ji Q, Zhang C, Xu Q, Wang Z, Li X, Lv Q.
    Br J Clin Pharmacol; 2021 May; 87(5):2247-2255. PubMed ID: 33179295
    [Abstract] [Full Text] [Related]

  • 22. Age-Dependent Human Hepatic Carboxylesterase 1 (CES1) and Carboxylesterase 2 (CES2) Postnatal Ontogeny.
    Hines RN, Simpson PM, McCarver DG.
    Drug Metab Dispos; 2016 Jul; 44(7):959-66. PubMed ID: 26825642
    [Abstract] [Full Text] [Related]

  • 23. CES1P1 variant -816A>C is not associated with hepatic carboxylesterase 1 expression and activity or antihypertensive effect of trandolapril.
    Zhu HJ, Langaee TY, Gong Y, Wang X, Pepine CJ, Cooper-DeHoff RM, Johnson JA, Markowitz JS.
    Eur J Clin Pharmacol; 2016 Jun; 72(6):681-7. PubMed ID: 26915813
    [Abstract] [Full Text] [Related]

  • 24. Impact of endogenous esterase activity on in vitro p-glycoprotein profiling of dabigatran etexilate in Caco-2 monolayers.
    Ishiguro N, Kishimoto W, Volz A, Ludwig-Schwellinger E, Ebner T, Schaefer O.
    Drug Metab Dispos; 2014 Feb; 42(2):250-6. PubMed ID: 24212377
    [Abstract] [Full Text] [Related]

  • 25. The Potentially Significant Role of CYP3A-Mediated Oxidative Metabolism of Dabigatran Etexilate and Its Intermediate Metabolites in Drug-Drug Interaction Assessments Using Microdose Dabigatran Etexilate.
    Udomnilobol U, Jianmongkol S, Prueksaritanont T.
    Drug Metab Dispos; 2023 Sep; 51(9):1216-1226. PubMed ID: 37230768
    [Abstract] [Full Text] [Related]

  • 26. Genetic variation in human carboxylesterase CES1 confers resistance to hepatic steatosis.
    Lian J, Bahitham W, Panigrahi R, Nelson R, Li L, Watts R, Thiesen A, Lemieux MJ, Lehner R.
    Biochim Biophys Acta Mol Cell Biol Lipids; 2018 Jul; 1863(7):688-699. PubMed ID: 29631096
    [Abstract] [Full Text] [Related]

  • 27. Effect of carboxylesterase 1 c.428G > A single nucleotide variation on the pharmacokinetics of quinapril and enalapril.
    Tarkiainen EK, Tornio A, Holmberg MT, Launiainen T, Neuvonen PJ, Backman JT, Niemi M.
    Br J Clin Pharmacol; 2015 Nov; 80(5):1131-8. PubMed ID: 25919042
    [Abstract] [Full Text] [Related]

  • 28. Clinical implications of genetic variation in carboxylesterase drug metabolism.
    Chen F, Zhang B, Parker RB, Laizure SC.
    Expert Opin Drug Metab Toxicol; 2018 Feb; 14(2):131-142. PubMed ID: 29264996
    [Abstract] [Full Text] [Related]

  • 29. Genetic variants of ABCB1 and CES1 genes on dabigatran metabolism in the Kazakh population.
    Abdrakhmanov A, Zholdybayeva E, Shaimerdinova A, Kulmambetova G, Abildinova S, Albayev R, Tuyakova G, Rib E, Suleimen Z, Abdrakhmanova Z, Bekbossynova M.
    Caspian J Intern Med; 2024 Feb; 15(3):499-508. PubMed ID: 39011438
    [Abstract] [Full Text] [Related]

  • 30. Effects of Genetic Variants on Carboxylesterase 1 Gene Expression, and Clopidogrel Pharmacokinetics and Antiplatelet Effects.
    Neuvonen M, Tarkiainen EK, Tornio A, Hirvensalo P, Tapaninen T, Paile-Hyvärinen M, Itkonen MK, Holmberg MT, Kärjä V, Männistö VT, Neuvonen PJ, Pihlajamäki J, Backman JT, Niemi M.
    Basic Clin Pharmacol Toxicol; 2018 Mar; 122(3):341-345. PubMed ID: 28990360
    [Abstract] [Full Text] [Related]

  • 31. Age- and sex-related expression and activity of carboxylesterase 1 and 2 in mouse and human liver.
    Zhu HJ, Appel DI, Jiang Y, Markowitz JS.
    Drug Metab Dispos; 2009 Sep; 37(9):1819-25. PubMed ID: 19487248
    [Abstract] [Full Text] [Related]

  • 32. Lymphatic Uptake of a Highly Lipophilic Protease Inhibitor Prodrug from a Lipid-Based Formulation is Limited by Instability in the Intestine.
    Xie Y, Lu Z, Styles IK, Reddiar SB, Phillips ARJ, Windsor JA, Porter CJH, Han S, Trevaskis NL.
    J Pharm Sci; 2024 Aug; 113(8):2342-2351. PubMed ID: 38582284
    [Abstract] [Full Text] [Related]

  • 33. The impact of ABCB1 (rs1045642 and rs4148738) and CES1 (rs2244613) gene polymorphisms on dabigatran equilibrium peak concentration in patients after total knee arthroplasty.
    Sychev DA, Levanov AN, Shelekhova TV, Bochkov PO, Denisenko NP, Ryzhikova KA, Mirzaev KB, Grishina EA, Gavrilov MA, Ramenskaya GV, Kozlov AV, Bogoslovsky T.
    Pharmgenomics Pers Med; 2018 Aug; 11():127-137. PubMed ID: 30100750
    [Abstract] [Full Text] [Related]

  • 34. Left atrial appendage thrombus formation in a patient with atrial fibrillation on dabigatran therapy associated with CES1 and ABCB1 genetic polymorphisms: A case report.
    Wu T, Xia X, Fu J, Chen W, Zhang J.
    Medicine (Baltimore); 2020 Sep 04; 99(36):e22084. PubMed ID: 32899083
    [Abstract] [Full Text] [Related]

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  • 36. Examination of the carboxylesterase phenotype in human liver.
    Ross MK, Borazjani A, Wang R, Crow JA, Xie S.
    Arch Biochem Biophys; 2012 Jun 01; 522(1):44-56. PubMed ID: 22525521
    [Abstract] [Full Text] [Related]

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  • 38. Development and validation of LC-MSMS assay for the determination of the prodrug dabigatran etexilate and its active metabolites in human plasma.
    Nouman EG, Al-Ghobashy MA, Lotfy HM.
    J Chromatogr B Analyt Technol Biomed Life Sci; 2015 May 01; 989():37-45. PubMed ID: 25797721
    [Abstract] [Full Text] [Related]

  • 39. Effects of alcohol on human carboxylesterase drug metabolism.
    Parker RB, Hu ZY, Meibohm B, Laizure SC.
    Clin Pharmacokinet; 2015 Jun 01; 54(6):627-38. PubMed ID: 25511794
    [Abstract] [Full Text] [Related]

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