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Journal Abstract Search

271 related items for PubMed ID: 27624080

  • 1. LAT1 activity of carboxylic acid bioisosteres: Evaluation of hydroxamic acids as substrates.
    Zur AA, Chien HC, Augustyn E, Flint A, Heeren N, Finke K, Hernandez C, Hansen L, Miller S, Lin L, Giacomini KM, Colas C, Schlessinger A, Thomas AA.
    Bioorg Med Chem Lett; 2016 Oct 15; 26(20):5000-5006. PubMed ID: 27624080
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  • 3. L-type amino acid transporter 1 utilizing prodrugs of ferulic acid revealed structural features supporting the design of prodrugs for brain delivery.
    Puris E, Gynther M, Huttunen J, Auriola S, Huttunen KM.
    Eur J Pharm Sci; 2019 Mar 01; 129():99-109. PubMed ID: 30625368
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  • 4. L-type amino acid transporter 1 utilizing prodrugs: How to achieve effective brain delivery and low systemic exposure of drugs.
    Puris E, Gynther M, Huttunen J, Petsalo A, Huttunen KM.
    J Control Release; 2017 Sep 10; 261():93-104. PubMed ID: 28662899
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  • 5. Amino acid ester prodrugs conjugated to the α-carboxylic acid group do not display affinity for the L-type amino acid transporter 1 (LAT1).
    Rautio J, Kärkkäinen J, Huttunen KM, Gynther M.
    Eur J Pharm Sci; 2015 Jan 23; 66():36-40. PubMed ID: 25305508
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  • 8. Quantitative insight into the design of compounds recognized by the L-type amino acid transporter 1 (LAT1).
    Ylikangas H, Malmioja K, Peura L, Gynther M, Nwachukwu EO, Leppänen J, Laine K, Rautio J, Lahtela-Kakkonen M, Huttunen KM, Poso A.
    ChemMedChem; 2014 Dec 23; 9(12):2699-707. PubMed ID: 25205473
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  • 9. Transport of Pregabalin Via L-Type Amino Acid Transporter 1 (SLC7A5) in Human Brain Capillary Endothelial Cell Line.
    Takahashi Y, Nishimura T, Higuchi K, Noguchi S, Tega Y, Kurosawa T, Deguchi Y, Tomi M.
    Pharm Res; 2018 Oct 29; 35(12):246. PubMed ID: 30374619
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  • 10. Structure-activity relationship study of compounds binding to large amino acid transporter 1 (LAT1) based on pharmacophore modeling and in situ rat brain perfusion.
    Ylikangas H, Peura L, Malmioja K, Leppänen J, Laine K, Poso A, Lahtela-Kakkonen M, Rautio J.
    Eur J Pharm Sci; 2013 Feb 14; 48(3):523-31. PubMed ID: 23228412
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  • 11. Site-directed mutagenesis of rabbit LAT1 at amino acids 219 and 234.
    Boado RJ, Li JY, Pardridge WM.
    J Neurochem; 2003 Mar 14; 84(6):1322-31. PubMed ID: 12614332
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  • 15. L-Type Amino Acid Transporter 1 (LAT1/Lat1)-Utilizing Prodrugs Can Improve the Delivery of Drugs into Neurons, Astrocytes and Microglia.
    Huttunen J, Peltokangas S, Gynther M, Natunen T, Hiltunen M, Auriola S, Ruponen M, Vellonen KS, Huttunen KM.
    Sci Rep; 2019 Sep 06; 9(1):12860. PubMed ID: 31492955
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  • 16. Large amino acid transporter 1 (LAT1) prodrugs of valproic acid: new prodrug design ideas for central nervous system delivery.
    Peura L, Malmioja K, Laine K, Leppänen J, Gynther M, Isotalo A, Rautio J.
    Mol Pharm; 2011 Oct 03; 8(5):1857-66. PubMed ID: 21770378
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  • 20. Developmental regulation of the rabbit blood-brain barrier LAT1 large neutral amino acid transporter mRNA and protein.
    Boado RJ, Li JY, Pardridge WM.
    Pediatr Res; 2004 Apr 03; 55(4):557-60. PubMed ID: 14764922
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