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Journal Abstract Search
246 related items for PubMed ID: 27634301
1. Identification of Doxorubicin as an Inhibitor of the IRE1α-XBP1 Axis of the Unfolded Protein Response. Jiang D, Lynch C, Medeiros BC, Liedtke M, Bam R, Tam AB, Yang Z, Alagappan M, Abidi P, Le QT, Giaccia AJ, Denko NC, Niwa M, Koong AC. Sci Rep; 2016 Sep 16; 6():33353. PubMed ID: 27634301 [Abstract] [Full Text] [Related]
2. Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma. Mimura N, Fulciniti M, Gorgun G, Tai YT, Cirstea D, Santo L, Hu Y, Fabre C, Minami J, Ohguchi H, Kiziltepe T, Ikeda H, Kawano Y, French M, Blumenthal M, Tam V, Kertesz NL, Malyankar UM, Hokenson M, Pham T, Zeng Q, Patterson JB, Richardson PG, Munshi NC, Anderson KC. Blood; 2012 Jun 14; 119(24):5772-81. PubMed ID: 22538852 [Abstract] [Full Text] [Related]
3. Acridine Derivatives as Inhibitors of the IRE1α-XBP1 Pathway Are Cytotoxic to Human Multiple Myeloma. Jiang D, Tam AB, Alagappan M, Hay MP, Gupta A, Kozak MM, Solow-Cordero DE, Lum PY, Denko NC, Giaccia AJ, Le QT, Niwa M, Koong AC. Mol Cancer Ther; 2016 Sep 14; 15(9):2055-65. PubMed ID: 27307600 [Abstract] [Full Text] [Related]
4. Farnesoid X receptor signaling activates the hepatic X-box binding protein 1 pathway in vitro and in mice. Liu X, Guo GL, Kong B, Hilburn DB, Hubchak SC, Park S, LeCuyer B, Hsieh A, Wang L, Fang D, Green RM. Hepatology; 2018 Jul 14; 68(1):304-316. PubMed ID: 29377207 [Abstract] [Full Text] [Related]
6. Inhibition of IRE1α-driven pro-survival pathways is a promising therapeutic application in acute myeloid leukemia. Sun H, Lin DC, Guo X, Kharabi Masouleh B, Gery S, Cao Q, Alkan S, Ikezoe T, Akiba C, Paquette R, Chien W, Müller-Tidow C, Jing Y, Agelopoulos K, Müschen M, Koeffler HP. Oncotarget; 2016 Apr 05; 7(14):18736-49. PubMed ID: 26934650 [Abstract] [Full Text] [Related]
7. Herpes Simplex Virus 1 UL41 Protein Suppresses the IRE1/XBP1 Signal Pathway of the Unfolded Protein Response via Its RNase Activity. Zhang P, Su C, Jiang Z, Zheng C. J Virol; 2017 Feb 15; 91(4):. PubMed ID: 27928013 [Abstract] [Full Text] [Related]
8. Screening and identification of inhibitors of endoplasmic reticulum stress-induced activation of the IRE1α-XBP1 branch. Tashiro E. J Antibiot (Tokyo); 2019 Dec 15; 72(12):899-905. PubMed ID: 31399644 [Abstract] [Full Text] [Related]
9. IRE1α/XBP1-mediated branch of the unfolded protein response regulates osteoclastogenesis. Tohmonda T, Yoda M, Iwawaki T, Matsumoto M, Nakamura M, Mikoshiba K, Toyama Y, Horiuchi K. J Clin Invest; 2015 Aug 03; 125(8):3269-79. PubMed ID: 26193638 [Abstract] [Full Text] [Related]
10. Opposite Roles of RNase and Kinase Activities of Inositol-Requiring Enzyme 1 (IRE1) on HSV-1 Replication. Su A, Wang H, Li Y, Wang X, Chen D, Wu Z. Viruses; 2017 Aug 23; 9(9):. PubMed ID: 28832521 [Abstract] [Full Text] [Related]
11. Resveratrol triggers the pro-apoptotic endoplasmic reticulum stress response and represses pro-survival XBP1 signaling in human multiple myeloma cells. Wang FM, Galson DL, Roodman GD, Ouyang H. Exp Hematol; 2011 Oct 23; 39(10):999-1006. PubMed ID: 21723843 [Abstract] [Full Text] [Related]
12. Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer. Zhao N, Cao J, Xu L, Tang Q, Dobrolecki LE, Lv X, Talukdar M, Lu Y, Wang X, Hu DZ, Shi Q, Xiang Y, Wang Y, Liu X, Bu W, Jiang Y, Li M, Gong Y, Sun Z, Ying H, Yuan B, Lin X, Feng XH, Hartig SM, Li F, Shen H, Chen Y, Han L, Zeng Q, Patterson JB, Kaipparettu BA, Putluri N, Sicheri F, Rosen JM, Lewis MT, Chen X. J Clin Invest; 2018 Apr 02; 128(4):1283-1299. PubMed ID: 29480818 [Abstract] [Full Text] [Related]
13. ER stress and distinct outputs of the IRE1α RNase control proliferation and senescence in response to oncogenic Ras. Blazanin N, Son J, Craig-Lucas AB, John CL, Breech KJ, Podolsky MA, Glick AB. Proc Natl Acad Sci U S A; 2017 Sep 12; 114(37):9900-9905. PubMed ID: 28847931 [Abstract] [Full Text] [Related]
14. Cyclosporine A binding to COX-2 reveals a novel signaling pathway that activates the IRE1α unfolded protein response sensor. Groenendyk J, Paskevicius T, Urra H, Viricel C, Wang K, Barakat K, Hetz C, Kurgan L, Agellon LB, Michalak M. Sci Rep; 2018 Nov 12; 8(1):16678. PubMed ID: 30420769 [Abstract] [Full Text] [Related]
15. The IRE1α-XBP1 arm of the unfolded protein response is a host factor activated in SARS-CoV-2 infection. Fernández JJ, Marín A, Rosales R, Penrice-Randal R, Mlcochova P, Alvarez Y, Villalón-Letelier F, Yildiz S, Pérez E, Rathnasinghe R, Cupic A, Kehrer T, Uccellini MB, Alonso S, Martínez F, McGovern BL, Clark JJ, Sharma P, Bayón Y, Alonso A, Albrecht RA, White KM, Schotsaert M, Miorin L, Stewart JP, Hiscox JA, Gupta RK, Irigoyen N, García-Sastre A, Crespo MS, Fernández N. Biochim Biophys Acta Mol Basis Dis; 2024 Jun 12; 1870(5):167193. PubMed ID: 38648902 [Abstract] [Full Text] [Related]
16. IRE1α-XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity. Song M, Sandoval TA, Chae CS, Chopra S, Tan C, Rutkowski MR, Raundhal M, Chaurio RA, Payne KK, Konrad C, Bettigole SE, Shin HR, Crowley MJP, Cerliani JP, Kossenkov AV, Motorykin I, Zhang S, Manfredi G, Zamarin D, Holcomb K, Rodriguez PC, Rabinovich GA, Conejo-Garcia JR, Glimcher LH, Cubillos-Ruiz JR. Nature; 2018 Oct 12; 562(7727):423-428. PubMed ID: 30305738 [Abstract] [Full Text] [Related]
17. IRE1α Promotes Zika Virus Infection via XBP1. Kolpikova EP, Tronco AR, Hartigh ABD, Jackson KJ, Iwawaki T, Fink SL. Viruses; 2020 Mar 03; 12(3):. PubMed ID: 32138181 [Abstract] [Full Text] [Related]
18. Unfolded protein response transducer IRE1-mediated signaling independent of XBP1 mRNA splicing is not required for growth and development of medaka fish. Ishikawa T, Kashima M, Nagano AJ, Ishikawa-Fujiwara T, Kamei Y, Todo T, Mori K. Elife; 2017 Sep 27; 6():. PubMed ID: 28952924 [Abstract] [Full Text] [Related]
19. IRE1α-XBP1 signaling in leukocytes controls prostaglandin biosynthesis and pain. Chopra S, Giovanelli P, Alvarado-Vazquez PA, Alonso S, Song M, Sandoval TA, Chae CS, Tan C, Fonseca MM, Gutierrez S, Jimenez L, Subbaramaiah K, Iwawaki T, Kingsley PJ, Marnett LJ, Kossenkov AV, Crespo MS, Dannenberg AJ, Glimcher LH, Romero-Sandoval EA, Cubillos-Ruiz JR. Science; 2019 Jul 19; 365(6450):. PubMed ID: 31320508 [Abstract] [Full Text] [Related]
20. IRE1α Activation in Bone Marrow-Derived Dendritic Cells Modulates Innate Recognition of Melanoma Cells and Favors CD8+ T Cell Priming. Medel B, Costoya C, Fernandez D, Pereda C, Lladser A, Sauma D, Pacheco R, Iwawaki T, Salazar-Onfray F, Osorio F. Front Immunol; 2018 Jul 19; 9():3050. PubMed ID: 30687308 [Abstract] [Full Text] [Related] Page: [Next] [New Search]