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Journal Abstract Search


417 related items for PubMed ID: 27641725

  • 1. Activation of the astrocytic Nrf2/ARE system ameliorates the formation of demyelinating lesions in a multiple sclerosis animal model.
    Draheim T, Liessem A, Scheld M, Wilms F, Weißflog M, Denecke B, Kensler TW, Zendedel A, Beyer C, Kipp M, Wruck CJ, Fragoulis A, Clarner T.
    Glia; 2016 Dec; 64(12):2219-2230. PubMed ID: 27641725
    [Abstract] [Full Text] [Related]

  • 2. Nrf2 deficiency increases oligodendrocyte loss, demyelination, neuroinflammation and axonal damage in an MS animal model.
    Nellessen A, Nyamoya S, Zendedel A, Slowik A, Wruck C, Beyer C, Fragoulis A, Clarner T.
    Metab Brain Dis; 2020 Feb; 35(2):353-362. PubMed ID: 31529356
    [Abstract] [Full Text] [Related]

  • 3. Astrocytic Nrf2 expression protects spinal cord from oxidative stress following spinal cord injury in a male mouse model.
    Zhao W, Gasterich N, Clarner T, Voelz C, Behrens V, Beyer C, Fragoulis A, Zendedel A.
    J Neuroinflammation; 2022 Jun 06; 19(1):134. PubMed ID: 35668451
    [Abstract] [Full Text] [Related]

  • 4. Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway.
    Linker RA, Lee DH, Ryan S, van Dam AM, Conrad R, Bista P, Zeng W, Hronowsky X, Buko A, Chollate S, Ellrichmann G, Brück W, Dawson K, Goelz S, Wiese S, Scannevin RH, Lukashev M, Gold R.
    Brain; 2011 Mar 06; 134(Pt 3):678-92. PubMed ID: 21354971
    [Abstract] [Full Text] [Related]

  • 5. Directly interact with Keap1 and LPS is involved in the anti-inflammatory mechanisms of (-)-epicatechin-3-gallate in LPS-induced macrophages and endotoxemia.
    Chiou YS, Huang Q, Ho CT, Wang YJ, Pan MH.
    Free Radic Biol Med; 2016 May 06; 94():1-16. PubMed ID: 26878775
    [Abstract] [Full Text] [Related]

  • 6. Astrocyte-targeted production of interleukin-6 reduces astroglial and microglial activation in the cuprizone demyelination model: Implications for myelin clearance and oligodendrocyte maturation.
    Petković F, Campbell IL, Gonzalez B, Castellano B.
    Glia; 2016 Dec 06; 64(12):2104-2119. PubMed ID: 27535761
    [Abstract] [Full Text] [Related]

  • 7. Electroacupuncture remediates glial dysfunction and ameliorates neurodegeneration in the astrocytic α-synuclein mutant mouse model.
    Deng J, Lv E, Yang J, Gong X, Zhang W, Liang X, Wang J, Jia J, Wang X.
    J Neuroinflammation; 2015 May 28; 12():103. PubMed ID: 26016857
    [Abstract] [Full Text] [Related]

  • 8. Isoflavone biochanin A, a novel nuclear factor erythroid 2-related factor 2 (Nrf2)-antioxidant response element activator, protects against oxidative damage in HepG2 cells.
    Liang F, Cao W, Huang Y, Fang Y, Cheng Y, Pan S, Xu X.
    Biofactors; 2019 Jul 28; 45(4):563-574. PubMed ID: 31131946
    [Abstract] [Full Text] [Related]

  • 9. Salvia miltiorrhiza Lipophilic Fraction Attenuates Oxidative Stress in Diabetic Nephropathy through Activation of Nuclear Factor Erythroid 2-Related Factor 2.
    An L, Zhou M, Marikar FMMT, Hu XW, Miao QY, Li P, Chen J.
    Am J Chin Med; 2017 Jul 28; 45(7):1441-1457. PubMed ID: 28946766
    [Abstract] [Full Text] [Related]

  • 10. Reduced cuprizone-induced cerebellar demyelination in mice with astrocyte-targeted production of IL-6 is associated with chronically activated, but less responsive microglia.
    Petković F, Campbell IL, Gonzalez B, Castellano B.
    J Neuroimmunol; 2017 Sep 15; 310():97-102. PubMed ID: 28778453
    [Abstract] [Full Text] [Related]

  • 11. Pyrrolidine dithiocarbamate activates the Nrf2 pathway in astrocytes.
    Liddell JR, Lehtonen S, Duncan C, Keksa-Goldsteine V, Levonen AL, Goldsteins G, Malm T, White AR, Koistinaho J, Kanninen KM.
    J Neuroinflammation; 2016 Feb 26; 13():49. PubMed ID: 26920699
    [Abstract] [Full Text] [Related]

  • 12. Melatonin receptor activation provides cerebral protection after traumatic brain injury by mitigating oxidative stress and inflammation via the Nrf2 signaling pathway.
    Wang J, Jiang C, Zhang K, Lan X, Chen X, Zang W, Wang Z, Guan F, Zhu C, Yang X, Lu H, Wang J.
    Free Radic Biol Med; 2019 Feb 01; 131():345-355. PubMed ID: 30553970
    [Abstract] [Full Text] [Related]

  • 13. Impaired antioxydative Keap1/Nrf2 system and the downstream stress protein responses in the motor neuron of ALS model mice.
    Mimoto T, Miyazaki K, Morimoto N, Kurata T, Satoh K, Ikeda Y, Abe K.
    Brain Res; 2012 Mar 29; 1446():109-18. PubMed ID: 22353756
    [Abstract] [Full Text] [Related]

  • 14. Carbon disulfide activates p62-Nrf2-keap1 pathway in rat nerve tissues.
    Wang S, Chen Y, Kou R, Wang Y, Zeng T, Xie K, Song F.
    Toxicology; 2016 Aug 10; 368-369():19-27. PubMed ID: 27530093
    [Abstract] [Full Text] [Related]

  • 15. TRPA1 deficiency is protective in cuprizone-induced demyelination-A new target against oligodendrocyte apoptosis.
    Sághy É, Sipos É, Ács P, Bölcskei K, Pohóczky K, Kemény Á, Sándor Z, Szőke É, Sétáló G, Komoly S, Pintér E.
    Glia; 2016 Dec 10; 64(12):2166-2180. PubMed ID: 27568827
    [Abstract] [Full Text] [Related]

  • 16. Neuroprotective effects of rutin against cuprizone-induced multiple sclerosis in mice.
    Nicola MA, Attaai AH, Abdel-Raheem MH, Mohammed AF, Abu-Elhassan YF.
    Inflammopharmacology; 2024 Apr 10; 32(2):1295-1315. PubMed ID: 38512652
    [Abstract] [Full Text] [Related]

  • 17. Blood-brain barrier hyperpermeability precedes demyelination in the cuprizone model.
    Berghoff SA, Düking T, Spieth L, Winchenbach J, Stumpf SK, Gerndt N, Kusch K, Ruhwedel T, Möbius W, Saher G.
    Acta Neuropathol Commun; 2017 Dec 01; 5(1):94. PubMed ID: 29195512
    [Abstract] [Full Text] [Related]

  • 18. Protection against oxidative stress mediated by the Nrf2/Keap1 axis is impaired in Primary Biliary Cholangitis.
    Wasik U, Milkiewicz M, Kempinska-Podhorodecka A, Milkiewicz P.
    Sci Rep; 2017 Mar 23; 7():44769. PubMed ID: 28333129
    [Abstract] [Full Text] [Related]

  • 19. Effects of deficiency of Kelch-like ECH-associated protein 1 on skeletal organization: a mechanism for diminished nuclear factor of activated T cells cytoplasmic 1 during osteoclastogenesis.
    Sakai E, Morita M, Ohuchi M, Kido MA, Fukuma Y, Nishishita K, Okamoto K, Itoh K, Yamamoto M, Tsukuba T.
    FASEB J; 2017 Sep 23; 31(9):4011-4022. PubMed ID: 28515152
    [Abstract] [Full Text] [Related]

  • 20. Cuprizone-induced graded oligodendrocyte vulnerability is regulated by the transcription factor DNA damage-inducible transcript 3.
    Fischbach F, Nedelcu J, Leopold P, Zhan J, Clarner T, Nellessen L, Beißel C, van Heuvel Y, Goswami A, Weis J, Denecke B, Schmitz C, Hochstrasser T, Nyamoya S, Victor M, Beyer C, Kipp M.
    Glia; 2019 Feb 23; 67(2):263-276. PubMed ID: 30511355
    [Abstract] [Full Text] [Related]


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