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Journal Abstract Search

187 related items for PubMed ID: 27665846

  • 1. Deacetylisovaltratum disrupts microtubule dynamics and causes G2/M-phase arrest in human gastric cancer cells in vitro.
    Zhang D, Zhang B, Zhou LX, Zhao J, Yan YY, Li YL, Zeng JM, Wang LL, Yang B, Lin NM.
    Acta Pharmacol Sin; 2016 Dec; 37(12):1597-1605. PubMed ID: 27665846
    [Abstract] [Full Text] [Related]

  • 2. DAT-230, a novel microtubule inhibitor, exhibits potent anti-tumor activity by inducing G2/M phase arrest, apoptosis in vitro and perfusion decrease in vivo to HT-1080.
    Qiao F, Zuo D, Shen X, Qi H, Wang H, Zhang W, Wu Y.
    Cancer Chemother Pharmacol; 2012 Aug; 70(2):259-70. PubMed ID: 22752214
    [Abstract] [Full Text] [Related]

  • 3. Induction of cytotoxicity and apoptosis in human gastric cancer cell SGC-7901 by isovaltrate acetoxyhydrin isolated from Patrinia heterophylla bunge involves a mitochondrial pathway and G2/M phase cell cycle arrest.
    Yang B, Wang YQ, Cheng RB, Chen JL, Chen J, Jia LT, Zhang RS.
    Asian Pac J Cancer Prev; 2013 Aug; 14(11):6481-6. PubMed ID: 24377554
    [Abstract] [Full Text] [Related]

  • 4. Synthesis of a terphenyl substituted 4-aza-2,3-didehydropodophyllotoxin analogues as inhibitors of tubulin polymerization and apoptosis inducers.
    Kamal A, Tamboli JR, Nayak VL, Adil SF, Vishnuvardhan MV, Ramakrishna S.
    Bioorg Med Chem; 2014 May 01; 22(9):2714-23. PubMed ID: 24721832
    [Abstract] [Full Text] [Related]

  • 5. Methyl 5-[(1H-indol-3-yl)selanyl]-1H-benzoimidazol-2-ylcarbamate (M-24), a novel tubulin inhibitor, causes G2/M arrest and cell apoptosis by disrupting tubulin polymerization in human cervical and breast cancer cells.
    Zuo D, Jiang X, Han M, Shen J, Lang B, Guan Q, Bai Z, Han C, Li Z, Zhang W, Wu Y.
    Toxicol In Vitro; 2017 Aug 01; 42():139-149. PubMed ID: 28412508
    [Abstract] [Full Text] [Related]

  • 6. Pyrrolotetrazinones deazaanalogues of temozolomide induce apoptosis in Jurkat cell line: involvement of tubulin polymerization inhibition.
    Viola G, Cecconet L, Leszl A, Basso G, Brun P, Salvador A, Dall'Acqua F, Diana P, Barraja P, Cirrincione G.
    Cancer Chemother Pharmacol; 2009 Nov 01; 64(6):1235-51. PubMed ID: 19363609
    [Abstract] [Full Text] [Related]

  • 7. 3-(3-Methoxyphenyl)-6-(3-amino-4-methoxyphenyl)-7H-[1,2,4] triazolo [3,4-b][1,3,4] thiadiazine, a novel tubulin inhibitor, evokes G2/M cell cycle arrest and apoptosis in SGC-7901 and HeLa cells.
    Liu Z, Lang B, Gao M, Chang X, Guan Q, Xu Q, Wu D, Li Z, Zuo D, Zhang W, Wu Y.
    J Cell Biochem; 2020 Mar 01; 121(3):2184-2196. PubMed ID: 31642107
    [Abstract] [Full Text] [Related]

  • 8. YSL-12, a novel microtubule-destabilizing agent, exerts potent anti-tumor activity against colon cancer in vitro and in vivo.
    Cai D, Qiu Z, Yao W, Liu Y, Huang H, Liao S, Luo Q, Xie L, Lin Z.
    Cancer Chemother Pharmacol; 2016 Jun 01; 77(6):1217-29. PubMed ID: 27107592
    [Abstract] [Full Text] [Related]

  • 9. Tivantinib induces G2/M arrest and apoptosis by disrupting tubulin polymerization in hepatocellular carcinoma.
    Xiang Q, Zhen Z, Deng DY, Wang J, Chen Y, Li J, Zhang Y, Wang F, Chen N, Chen H, Chen Y.
    J Exp Clin Cancer Res; 2015 Oct 12; 34():118. PubMed ID: 26458953
    [Abstract] [Full Text] [Related]

  • 10. A Novel Resveratrol Based Tubulin Inhibitor Induces Mitotic Arrest and Activates Apoptosis in Cancer Cells.
    Thomas E, Gopalakrishnan V, Hegde M, Kumar S, Karki SS, Raghavan SC, Choudhary B.
    Sci Rep; 2016 Oct 17; 6():34653. PubMed ID: 27748367
    [Abstract] [Full Text] [Related]

  • 11. 5-(Furan-2-yl)-4-(3,4,5-trimethoxyphenyl)-3H-1,2-dithiol-3-one oxime (6f), a new synthetic compound, causes human fibrosarcoma HT-1080 cell apoptosis by disrupting tubulin polymerisation and inducing G2/M arrest.
    Zuo D, Pang L, Shen J, Guan Q, Bai Z, Zhang H, Li Y, Lu G, Zhang W, Wu Y.
    Int J Oncol; 2017 Jun 17; 50(6):2069-2078. PubMed ID: 28440465
    [Abstract] [Full Text] [Related]

  • 12. Synthesis and biological evaluation of quinoxaline derivatives as tubulin polymerization inhibitors that elevate intracellular ROS and triggers apoptosis via mitochondrial pathway.
    Qi J, Huang J, Zhou X, Luo W, Xie J, Niu L, Yan Z, Luo Y, Men Y, Chen Y, Zhang Y, Wang J.
    Chem Biol Drug Des; 2019 Apr 17; 93(4):617-627. PubMed ID: 30635972
    [Abstract] [Full Text] [Related]

  • 13. Synthesis of C5-tethered indolyl-3-glyoxylamide derivatives as tubulin polymerization inhibitors.
    Guggilapu SD, Lalita G, Reddy TS, Prajapti SK, Nagarsenkar A, Ramu S, Brahma UR, Lakshmi UJ, Vegi GMN, Bhargava SK, Babu BN.
    Eur J Med Chem; 2017 Mar 10; 128():1-12. PubMed ID: 28131777
    [Abstract] [Full Text] [Related]

  • 14. (4-Methoxyphenyl)(3,4,5-trimethoxyphenyl)methanone inhibits tubulin polymerization, induces G2/M arrest, and triggers apoptosis in human leukemia HL-60 cells.
    Magalhães HI, Wilke DV, Bezerra DP, Cavalcanti BC, Rotta R, de Lima DP, Beatriz A, Moraes MO, Diniz-Filho J, Pessoa C.
    Toxicol Appl Pharmacol; 2013 Oct 01; 272(1):117-26. PubMed ID: 23756174
    [Abstract] [Full Text] [Related]

  • 15. Discovery of novel quinazolines as potential anti-tubulin agents occupying three zones of colchicine domain.
    Li W, Yin Y, Shuai W, Xu F, Yao H, Liu J, Cheng K, Xu J, Zhu Z, Xu S.
    Bioorg Chem; 2019 Mar 01; 83():380-390. PubMed ID: 30408650
    [Abstract] [Full Text] [Related]

  • 16. MT-4 suppresses resistant ovarian cancer growth through targeting tubulin and HSP27.
    Pai HC, Kumar S, Shen CC, Liou JP, Pan SL, Teng CM.
    PLoS One; 2015 Mar 01; 10(4):e0123819. PubMed ID: 25874627
    [Abstract] [Full Text] [Related]

  • 17. Novel tubulin-polymerization inhibitor derived from thalidomide directly induces apoptosis in human multiple myeloma cells: possible anti-myeloma mechanism of thalidomide.
    Iguchi T, Yachide-Noguchi T, Hashimoto Y, Nakazato S, Sagawa M, Ikeda Y, Kizaki M.
    Int J Mol Med; 2008 Feb 01; 21(2):163-8. PubMed ID: 18204782
    [Abstract] [Full Text] [Related]

  • 18. Decitabine, a DNA methyltransferases inhibitor, induces cell cycle arrest at G2/M phase through p53-independent pathway in human cancer cells.
    Shin DY, Sung Kang H, Kim GY, Kim WJ, Yoo YH, Choi YH.
    Biomed Pharmacother; 2013 May 01; 67(4):305-11. PubMed ID: 23582784
    [Abstract] [Full Text] [Related]

  • 19. Inhibition of mitotic Aurora kinase A by alisertib induces apoptosis and autophagy of human gastric cancer AGS and NCI-N78 cells.
    Yuan CX, Zhou ZW, Yang YX, He ZX, Zhang X, Wang D, Yang T, Wang NJ, Zhao RJ, Zhou SF.
    Drug Des Devel Ther; 2015 May 01; 9():487-508. PubMed ID: 25609923
    [Abstract] [Full Text] [Related]

  • 20. NMK-TD-100, a novel microtubule modulating agent, blocks mitosis and induces apoptosis in HeLa cells by binding to tubulin.
    Bhattacharya S, Kumar NM, Ganguli A, Tantak MP, Kumar D, Chakrabarti G.
    PLoS One; 2013 May 01; 8(10):e76286. PubMed ID: 24116100
    [Abstract] [Full Text] [Related]

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