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228 related items for PubMed ID: 27665850

  • 1. Ferulic acid prevents LPS-induced up-regulation of PDE4B and stimulates the cAMP/CREB signaling pathway in PC12 cells.
    Huang H, Hong Q, Tan HL, Xiao CR, Gao Y.
    Acta Pharmacol Sin; 2016 Dec; 37(12):1543-1554. PubMed ID: 27665850
    [Abstract] [Full Text] [Related]

  • 2. Phosphodiesterase 4B negatively regulates endotoxin-activated interleukin-1 receptor antagonist responses in macrophages.
    Yang JX, Hsieh KC, Chen YL, Lee CK, Conti M, Chuang TH, Wu CP, Jin SC.
    Sci Rep; 2017 Apr 06; 7():46165. PubMed ID: 28383060
    [Abstract] [Full Text] [Related]

  • 3. Etazolate abrogates the lipopolysaccharide (LPS)-induced downregulation of the cAMP/pCREB/BDNF signaling, neuroinflammatory response and depressive-like behavior in mice.
    Guo J, Lin P, Zhao X, Zhang J, Wei X, Wang Q, Wang C.
    Neuroscience; 2014 Mar 28; 263():1-14. PubMed ID: 24434771
    [Abstract] [Full Text] [Related]

  • 4. Ferulic acid alleviates Aβ25-35- and lipopolysaccharide-induced PC12 cellular damage: a potential role in Alzheimer's disease by PDE inhibition.
    Huang H, Ma ZC, Wang YG, Hong Q, Tan HL, Xiao CR, Liang QD, Tang XL, Gao Y.
    Int J Clin Pharmacol Ther; 2015 Oct 28; 53(10):828-37. PubMed ID: 26308168
    [Abstract] [Full Text] [Related]

  • 5. Specific role of phosphodiesterase 4B in lipopolysaccharide-induced signaling in mouse macrophages.
    Jin SL, Lan L, Zoudilova M, Conti M.
    J Immunol; 2005 Aug 01; 175(3):1523-31. PubMed ID: 16034090
    [Abstract] [Full Text] [Related]

  • 6. Action of rolipram on specific PDE4 cAMP phosphodiesterase isoforms and on the phosphorylation of cAMP-response-element-binding protein (CREB) and p38 mitogen-activated protein (MAP) kinase in U937 monocytic cells.
    MacKenzie SJ, Houslay MD.
    Biochem J; 2000 Apr 15; 347(Pt 2):571-8. PubMed ID: 10749688
    [Abstract] [Full Text] [Related]

  • 7. Nobiletin, as a Novel PDE4B Inhibitor, Alleviates Asthma Symptoms by Activating the cAMP-PKA-CREB Signaling Pathway.
    Zhang Y, Yang Y, Liang H, Liang Y, Xiong G, Lu F, Yang K, Zou Q, Zhang X, Du G, Xu X, Hao J.
    Int J Mol Sci; 2024 Sep 27; 25(19):. PubMed ID: 39408735
    [Abstract] [Full Text] [Related]

  • 8. S-adenosylmethionine decreases lipopolysaccharide-induced phosphodiesterase 4B2 and attenuates tumor necrosis factor expression via cAMP/protein kinase A pathway.
    Gobejishvili L, Avila DV, Barker DF, Ghare S, Henderson D, Brock GN, Kirpich IA, Joshi-Barve S, Mokshagundam SP, McClain CJ, Barve S.
    J Pharmacol Exp Ther; 2011 May 27; 337(2):433-43. PubMed ID: 21266552
    [Abstract] [Full Text] [Related]

  • 9. Regulation of cAMP-specific phosphodiesterases type 4B and 4D (PDE4) splice variants by cAMP signaling in primary cortical neurons.
    D'Sa C, Tolbert LM, Conti M, Duman RS.
    J Neurochem; 2002 May 27; 81(4):745-57. PubMed ID: 12065634
    [Abstract] [Full Text] [Related]

  • 10. Pivotal role of cAMP-PKA-CREB signaling pathway in manganese-induced neurotoxicity in PC12 cells.
    Yang Y, Ma S, Wei F, Liang G, Yang X, Huang Y, Wang J, Zou Y.
    Environ Toxicol; 2019 Sep 27; 34(9):1052-1062. PubMed ID: 31161640
    [Abstract] [Full Text] [Related]

  • 11. Phosphodiesterase 4b expression plays a major role in alcohol-induced neuro-inflammation.
    Avila DV, Myers SA, Zhang J, Kharebava G, McClain CJ, Kim HY, Whittemore SR, Gobejishvili L, Barve S.
    Neuropharmacology; 2017 Oct 27; 125():376-385. PubMed ID: 28807677
    [Abstract] [Full Text] [Related]

  • 12. Novel Phosphodiesterase 4 Inhibitor FCPR03 Alleviates Lipopolysaccharide-Induced Neuroinflammation by Regulation of the cAMP/PKA/CREB Signaling Pathway and NF-κB Inhibition.
    Zou ZQ, Chen JJ, Feng HF, Cheng YF, Wang HT, Zhou ZZ, Guo HB, Zheng W, Xu JP.
    J Pharmacol Exp Ther; 2017 Jul 27; 362(1):67-77. PubMed ID: 28450469
    [Abstract] [Full Text] [Related]

  • 13. Noradrenergic lesions differentially alter the expression of two subtypes of low Km cAMP-sensitive phosphodiesterase type 4 (PDE4A and PDE4B) in rat brain.
    Farooqui SM, Zhang K, Makhay M, Jackson K, Farooqui SQ, Cherry JA, O'Donnell JM.
    Brain Res; 2000 Jun 09; 867(1-2):52-61. PubMed ID: 10837797
    [Abstract] [Full Text] [Related]

  • 14. Phosphodiesterase 4B gene transcription is activated by lipopolysaccharide and inhibited by interleukin-10 in human monocytes.
    Ma D, Wu P, Egan RW, Billah MM, Wang P.
    Mol Pharmacol; 1999 Jan 09; 55(1):50-7. PubMed ID: 9882697
    [Abstract] [Full Text] [Related]

  • 15. Chronic Cognitive Dysfunction after Traumatic Brain Injury Is Improved with a Phosphodiesterase 4B Inhibitor.
    Titus DJ, Wilson NM, Freund JE, Carballosa MM, Sikah KE, Furones C, Dietrich WD, Gurney ME, Atkins CM.
    J Neurosci; 2016 Jul 06; 36(27):7095-108. PubMed ID: 27383587
    [Abstract] [Full Text] [Related]

  • 16. Ferulic acid positively modulates the inflammatory response to septic liver injury through the GSK-3β/NF-κB/CREB pathway.
    Cao L, Li Z, Yang Z, Wang M, Zhang W, Ren Y, Li L, Hu J, Sun Z, Nie S.
    Life Sci; 2021 Jul 15; 277():119584. PubMed ID: 33961853
    [Abstract] [Full Text] [Related]

  • 17. Proinflammatory cytokine regulation of cyclic AMP-phosphodiesterase 4 signaling in microglia in vitro and following CNS injury.
    Ghosh M, Garcia-Castillo D, Aguirre V, Golshani R, Atkins CM, Bramlett HM, Dietrich WD, Pearse DD.
    Glia; 2012 Dec 15; 60(12):1839-59. PubMed ID: 22865690
    [Abstract] [Full Text] [Related]

  • 18. Specific Inhibition of Phosphodiesterase-4B Results in Anxiolysis and Facilitates Memory Acquisition.
    McGirr A, Lipina TV, Mun HS, Georgiou J, Al-Amri AH, Ng E, Zhai D, Elliott C, Cameron RT, Mullins JG, Liu F, Baillie GS, Clapcote SJ, Roder JC.
    Neuropsychopharmacology; 2016 Mar 15; 41(4):1080-92. PubMed ID: 26272049
    [Abstract] [Full Text] [Related]

  • 19. Induction of the cyclic nucleotide phosphodiesterase PDE4B is essential for LPS-activated TNF-alpha responses.
    Jin SL, Conti M.
    Proc Natl Acad Sci U S A; 2002 May 28; 99(11):7628-33. PubMed ID: 12032334
    [Abstract] [Full Text] [Related]

  • 20. Citrus flavonoid 3,5,6,7,8,3',4'-heptamethoxyflavone induces BDNF via cAMP/ERK/CREB signaling and reduces phosphodiesterase activity in C6 cells.
    Sawamoto A, Okuyama S, Nakajima M, Furukawa Y.
    Pharmacol Rep; 2019 Aug 28; 71(4):653-658. PubMed ID: 31195342
    [Abstract] [Full Text] [Related]

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