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226 related items for PubMed ID: 27678284

  • 1. Drug metabolism by flavin-containing monooxygenases of human and mouse.
    Phillips IR, Shephard EA.
    Expert Opin Drug Metab Toxicol; 2017 Feb; 13(2):167-181. PubMed ID: 27678284
    [Abstract] [Full Text] [Related]

  • 2. The potential of knockout mouse lines in defining the role of flavin-containing monooxygenases in drug metabolism.
    Shephard EA, Phillips IR.
    Expert Opin Drug Metab Toxicol; 2010 Sep; 6(9):1083-94. PubMed ID: 20629583
    [Abstract] [Full Text] [Related]

  • 3. Mammalian flavin-containing monooxygenases: structure/function, genetic polymorphisms and role in drug metabolism.
    Krueger SK, Williams DE.
    Pharmacol Ther; 2005 Jun; 106(3):357-87. PubMed ID: 15922018
    [Abstract] [Full Text] [Related]

  • 4. Flavin-containing monooxygenases: mutations, disease and drug response.
    Phillips IR, Shephard EA.
    Trends Pharmacol Sci; 2008 Jun; 29(6):294-301. PubMed ID: 18423897
    [Abstract] [Full Text] [Related]

  • 5. Some distinctions between flavin-containing and cytochrome P450 monooxygenases.
    Cashman JR.
    Biochem Biophys Res Commun; 2005 Dec 09; 338(1):599-604. PubMed ID: 16112078
    [Abstract] [Full Text] [Related]

  • 6. The implications of polymorphisms in mammalian flavin-containing monooxygenases in drug discovery and development.
    Cashman JR.
    Drug Discov Today; 2004 Jul 01; 9(13):574-81. PubMed ID: 15203093
    [Abstract] [Full Text] [Related]

  • 7. Isoform specificity of N-deacetyl ketoconazole by human and rabbit flavin-containing monooxygenases.
    Rodriguez RJ, Miranda CL.
    Drug Metab Dispos; 2000 Sep 01; 28(9):1083-6. PubMed ID: 10950853
    [Abstract] [Full Text] [Related]

  • 8. Alternative processing events in human FMO genes.
    Lattard V, Zhang J, Cashman JR.
    Mol Pharmacol; 2004 Jun 01; 65(6):1517-25. PubMed ID: 15155844
    [Abstract] [Full Text] [Related]

  • 9. Quantification and cellular localization of expression in human skin of genes encoding flavin-containing monooxygenases and cytochromes P450.
    Janmohamed A, Dolphin CT, Phillips IR, Shephard EA.
    Biochem Pharmacol; 2001 Sep 15; 62(6):777-86. PubMed ID: 11551524
    [Abstract] [Full Text] [Related]

  • 10. The phenotype of a flavin-containing monooyxgenase knockout mouse implicates the drug-metabolizing enzyme FMO1 as a novel regulator of energy balance.
    Veeravalli S, Omar BA, Houseman L, Hancock M, Gonzalez Malagon SG, Scott F, Janmohamed A, Phillips IR, Shephard EA.
    Biochem Pharmacol; 2014 Jul 01; 90(1):88-95. PubMed ID: 24792439
    [Abstract] [Full Text] [Related]

  • 11. A variety of cytochrome P450 enzymes and flavin-containing monooxygenases in dogs and pigs commonly used as preclinical animal models.
    Uno Y, Shimizu M, Yamazaki H.
    Biochem Pharmacol; 2024 Oct 01; 228():116124. PubMed ID: 38490520
    [Abstract] [Full Text] [Related]

  • 12. In vitro evaluation of potential in vivo probes for human flavin-containing monooxygenase (FMO): metabolism of benzydamine and caffeine by FMO and P450 isoforms.
    Lang DH, Rettie AE.
    Br J Clin Pharmacol; 2000 Oct 01; 50(4):311-4. PubMed ID: 11012553
    [Abstract] [Full Text] [Related]

  • 13. Deletion of the mouse Fmo1 gene results in enhanced pharmacological behavioural responses to imipramine.
    Hernandez D, Janmohamed A, Chandan P, Omar BA, Phillips IR, Shephard EA.
    Pharmacogenet Genomics; 2009 Apr 01; 19(4):289-99. PubMed ID: 19262426
    [Abstract] [Full Text] [Related]

  • 14. Cell-, tissue-, sex- and developmental stage-specific expression of mouse flavin-containing monooxygenases (Fmos).
    Janmohamed A, Hernandez D, Phillips IR, Shephard EA.
    Biochem Pharmacol; 2004 Jul 01; 68(1):73-83. PubMed ID: 15183119
    [Abstract] [Full Text] [Related]

  • 15. Regioselective oxidation of phospho-NSAIDs by human cytochrome P450 and flavin monooxygenase isoforms: implications for their pharmacokinetic properties and safety.
    Xie G, Wong CC, Cheng KW, Huang L, Constantinides PP, Rigas B.
    Br J Pharmacol; 2012 Sep 01; 167(1):222-32. PubMed ID: 22489789
    [Abstract] [Full Text] [Related]

  • 16. Predicting reactivity to drug metabolism: beyond P450s-modelling FMOs and UGTs.
    Öeren M, Walton PJ, Hunt PA, Ponting DJ, Segall MD.
    J Comput Aided Mol Des; 2021 Apr 01; 35(4):541-555. PubMed ID: 32533369
    [Abstract] [Full Text] [Related]

  • 17. Molecular and functional characterization of flavin-containing monooxygenases in cynomolgus macaque.
    Uno Y, Shimizu M, Yamazaki H.
    Biochem Pharmacol; 2013 Jun 15; 85(12):1837-47. PubMed ID: 23623750
    [Abstract] [Full Text] [Related]

  • 18. The participation of human hepatic P450 isoforms, flavin-containing monooxygenases and aldehyde oxidase in the biotransformation of the insecticide fenthion.
    Leoni C, Buratti FM, Testai E.
    Toxicol Appl Pharmacol; 2008 Dec 01; 233(2):343-52. PubMed ID: 18845175
    [Abstract] [Full Text] [Related]

  • 19. Developmental expression and regulation of flavin-containing monooxygenase by the unfolded protein response in Japanese medaka (Oryzias latipes).
    Kupsco A, Schlenk D.
    Comp Biochem Physiol C Toxicol Pharmacol; 2017 Jan 01; 191():7-13. PubMed ID: 27612667
    [Abstract] [Full Text] [Related]

  • 20. Differential localization of flavin-containing monooxygenase (FMO) isoforms 1, 3, and 4 in rat liver and kidney and evidence for expression of FMO4 in mouse, rat, and human liver and kidney microsomes.
    Novick RM, Mitzey AM, Brownfield MS, Elfarra AA.
    J Pharmacol Exp Ther; 2009 Jun 01; 329(3):1148-55. PubMed ID: 19307449
    [Abstract] [Full Text] [Related]

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