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Journal Abstract Search

220 related items for PubMed ID: 27715044

  • 1. The Activation of c-Src Tyrosine Kinase: Conformational Transition Pathway and Free Energy Landscape.
    Fajer M, Meng Y, Roux B.
    J Phys Chem B; 2017 Apr 20; 121(15):3352-3363. PubMed ID: 27715044
    [Abstract] [Full Text] [Related]

  • 2. Tyrosine Kinase Activation and Conformational Flexibility: Lessons from Src-Family Tyrosine Kinases.
    Meng Y, Pond MP, Roux B.
    Acc Chem Res; 2017 May 16; 50(5):1193-1201. PubMed ID: 28426203
    [Abstract] [Full Text] [Related]

  • 3. On the importance of a funneled energy landscape for the assembly and regulation of multidomain Src tyrosine kinases.
    Faraldo-Gómez JD, Roux B.
    Proc Natl Acad Sci U S A; 2007 Aug 21; 104(34):13643-8. PubMed ID: 17699616
    [Abstract] [Full Text] [Related]

  • 4. An electrostatic network and long-range regulation of Src kinases.
    Ozkirimli E, Yadav SS, Miller WT, Post CB.
    Protein Sci; 2008 Nov 21; 17(11):1871-80. PubMed ID: 18687871
    [Abstract] [Full Text] [Related]

  • 5. Roles of the SH2 and SH3 domains in the regulation of neuronal Src kinase functions.
    Groveman BR, Xue S, Marin V, Xu J, Ali MK, Bienkiewicz EA, Yu XM.
    FEBS J; 2011 Feb 21; 278(4):643-53. PubMed ID: 21199370
    [Abstract] [Full Text] [Related]

  • 6. Src protein-tyrosine kinase structure and regulation.
    Roskoski R.
    Biochem Biophys Res Commun; 2004 Nov 26; 324(4):1155-64. PubMed ID: 15504335
    [Abstract] [Full Text] [Related]

  • 7. Csk αC Helix: A Computational Analysis of an Essential Region for Conformational Transitions.
    Dias RVR, Ferreira CTA, Jennings PA, Whitford PC, Oliveira LC.
    J Phys Chem B; 2022 Dec 22; 126(50):10587-10596. PubMed ID: 36512419
    [Abstract] [Full Text] [Related]

  • 8. Molecular Dynamics Simulations and Structural Network Analysis of c-Abl and c-Src Kinase Core Proteins: Capturing Allosteric Mechanisms and Communication Pathways from Residue Centrality.
    Tse A, Verkhivker GM.
    J Chem Inf Model; 2015 Aug 24; 55(8):1645-62. PubMed ID: 26236953
    [Abstract] [Full Text] [Related]

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  • 10. Binding, domain orientation, and dynamics of the Lck SH3-SH2 domain pair and comparison with other Src-family kinases.
    Hofmann G, Schweimer K, Kiessling A, Hofinger E, Bauer F, Hoffmann S, Rösch P, Campbell ID, Werner JM, Sticht H.
    Biochemistry; 2005 Oct 04; 44(39):13043-50. PubMed ID: 16185072
    [Abstract] [Full Text] [Related]

  • 11. Novel mechanism of regulation of the non-receptor protein tyrosine kinase Csk: insights from NMR mapping studies and site-directed mutagenesis.
    Shekhtman A, Ghose R, Wang D, Cole PA, Cowburn D.
    J Mol Biol; 2001 Nov 16; 314(1):129-38. PubMed ID: 11724538
    [Abstract] [Full Text] [Related]

  • 12. Mapping the conformational transition in Src activation by cumulating the information from multiple molecular dynamics trajectories.
    Yang S, Banavali NK, Roux B.
    Proc Natl Acad Sci U S A; 2009 Mar 10; 106(10):3776-81. PubMed ID: 19225111
    [Abstract] [Full Text] [Related]

  • 13. Targeting Self-Binding Peptides as a Novel Strategy To Regulate Protein Activity and Function: A Case Study on the Proto-oncogene Tyrosine Protein Kinase c-Src.
    Bai Z, Hou S, Zhang S, Li Z, Zhou P.
    J Chem Inf Model; 2017 Apr 24; 57(4):835-845. PubMed ID: 28345935
    [Abstract] [Full Text] [Related]

  • 14. Theoretical Insights Reveal Novel Motions in Csk's SH3 Domain That Control Kinase Activation.
    Barkho S, Pierce LC, Li S, Adams JA, Jennings PA.
    PLoS One; 2015 Apr 24; 10(6):e0127724. PubMed ID: 26030592
    [Abstract] [Full Text] [Related]

  • 15. Locking the active conformation of c-Src kinase through the phosphorylation of the activation loop.
    Meng Y, Roux B.
    J Mol Biol; 2014 Jan 23; 426(2):423-35. PubMed ID: 24103328
    [Abstract] [Full Text] [Related]

  • 16. Disordered Domain Shifts the Conformational Ensemble of the Folded Regulatory Domain of the Multidomain Oncoprotein c-Src.
    Gurumoorthy V, Shrestha UR, Zhang Q, Pingali SV, Boder ET, Urban VS, Smith JC, Petridis L, O'Neill H.
    Biomacromolecules; 2023 Feb 13; 24(2):714-723. PubMed ID: 36692364
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  • 18. Conformational basis for SH2-Tyr(P)527 binding in Src inactivation.
    Ayrapetov MK, Wang YH, Lin X, Gu X, Parang K, Sun G.
    J Biol Chem; 2006 Aug 18; 281(33):23776-84. PubMed ID: 16790421
    [Abstract] [Full Text] [Related]

  • 19. The evolutionarily conserved arrangement of domains in SRC family kinases is important for substrate recognition.
    Yadav SS, Miller WT.
    Biochemistry; 2008 Oct 14; 47(41):10871-80. PubMed ID: 18803405
    [Abstract] [Full Text] [Related]

  • 20. SH3-dependent stimulation of Src-family kinase autophosphorylation without tail release from the SH2 domain in vivo.
    Lerner EC, Smithgall TE.
    Nat Struct Biol; 2002 May 14; 9(5):365-9. PubMed ID: 11976726
    [Abstract] [Full Text] [Related]

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