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Journal Abstract Search

367 related items for PubMed ID: 27721157

  • 1. Design, synthesis, in-silico and biological evaluation of novel donepezil derivatives as multi-target-directed ligands for the treatment of Alzheimer's disease.
    Mishra CB, Kumari S, Manral A, Prakash A, Saini V, Lynn AM, Tiwari M.
    Eur J Med Chem; 2017 Jan 05; 125():736-750. PubMed ID: 27721157
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  • 2. Design, synthesis and evaluation of novel indandione derivatives as multifunctional agents with cholinesterase inhibition, anti-β-amyloid aggregation, antioxidant and neuroprotection properties against Alzheimer's disease.
    Mishra CB, Manral A, Kumari S, Saini V, Tiwari M.
    Bioorg Med Chem; 2016 Aug 15; 24(16):3829-41. PubMed ID: 27353888
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  • 7. Design, synthesis, and evaluation of multitarget-directed ligands against Alzheimer's disease based on the fusion of donepezil and curcumin.
    Yan J, Hu J, Liu A, He L, Li X, Wei H.
    Bioorg Med Chem; 2017 Jun 15; 25(12):2946-2955. PubMed ID: 28454848
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  • 10. Design, synthesis and biological evaluation of novel donepezil-coumarin hybrids as multi-target agents for the treatment of Alzheimer's disease.
    Xie SS, Lan JS, Wang X, Wang ZM, Jiang N, Li F, Wu JJ, Wang J, Kong LY.
    Bioorg Med Chem; 2016 Apr 01; 24(7):1528-39. PubMed ID: 26917219
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  • 11. Donepezil-butylated hydroxytoluene (BHT) hybrids as Anti-Alzheimer's disease agents with cholinergic, antioxidant, and neuroprotective properties.
    Cai P, Fang SQ, Yang HL, Yang XL, Liu QH, Kong LY, Wang XB.
    Eur J Med Chem; 2018 Sep 05; 157():161-176. PubMed ID: 30096650
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  • 12. Synthesis, biological evaluation and molecular docking study of novel piperidine and piperazine derivatives as multi-targeted agents to treat Alzheimer's disease.
    Meena P, Nemaysh V, Khatri M, Manral A, Luthra PM, Tiwari M.
    Bioorg Med Chem; 2015 Mar 01; 23(5):1135-48. PubMed ID: 25624107
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  • 14. Novel Multitarget Directed Triazinoindole Derivatives as Anti-Alzheimer Agents.
    Patel DV, Patel NR, Kanhed AM, Patel SP, Sinha A, Kansara DD, Mecwan AR, Patel SB, Upadhyay PN, Patel KB, Shah DB, Prajapati NK, Murumkar PR, Patel KV, Yadav MR.
    ACS Chem Neurosci; 2019 Aug 21; 10(8):3635-3661. PubMed ID: 31310717
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  • 15. Donepezil-based multi-functional cholinesterase inhibitors for treatment of Alzheimer's disease.
    Li Q, He S, Chen Y, Feng F, Qu W, Sun H.
    Eur J Med Chem; 2018 Oct 05; 158():463-477. PubMed ID: 30243151
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  • 16. Design, synthesis and evaluation of novel bivalent β-carboline derivatives as multifunctional agents for the treatment of Alzheimer's disease.
    Zhao Y, Ye F, Xu J, Liao Q, Chen L, Zhang W, Sun H, Liu W, Feng F, Qu W.
    Bioorg Med Chem; 2018 Jul 30; 26(13):3812-3824. PubMed ID: 29960728
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  • 17. Synthesis, in vitro assay, and molecular modeling of new piperidine derivatives having dual inhibitory potency against acetylcholinesterase and Abeta1-42 aggregation for Alzheimer's disease therapeutics.
    Kwon YE, Park JY, No KT, Shin JH, Lee SK, Eun JS, Yang JH, Shin TY, Kim DK, Chae BS, Leem JY, Kim KH.
    Bioorg Med Chem; 2007 Oct 15; 15(20):6596-607. PubMed ID: 17681794
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  • 18. 6-Methyluracil derivatives as acetylcholinesterase inhibitors for treatment of Alzheimer's disease.
    Zueva IV, Semenov VE, Mukhamedyarov MA, Lushchekina SV, Kharlamova AD, Petukhova EO, Mikhailov AS, Podyachev SN, Saifina LF, Petrov KA, Minnekhanova OA, Zobov VV, Nikolsky EE, Masson P, Reznik VS.
    Int J Risk Saf Med; 2015 Oct 15; 27 Suppl 1():S69-71. PubMed ID: 26639718
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