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Journal Abstract Search

312 related items for PubMed ID: 27748367

  • 1.
    ; . PubMed ID:
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  • 2. Identification of novel 1-indolyl acetate-5-nitroimidazole derivatives of combretastatin A-4 as potential tubulin polymerization inhibitors.
    Yao YF, Wang ZC, Wu SY, Li QF, Yu C, Liang XY, Lv PC, Duan YT, Zhu HL.
    Biochem Pharmacol; 2017 Aug 01; 137():10-28. PubMed ID: 28456516
    [Abstract] [Full Text] [Related]

  • 3. Thymoquinone inhibits microtubule polymerization by tubulin binding and causes mitotic arrest following apoptosis in A549 cells.
    Acharya BR, Chatterjee A, Ganguli A, Bhattacharya S, Chakrabarti G.
    Biochimie; 2014 Feb 01; 97():78-91. PubMed ID: 24113316
    [Abstract] [Full Text] [Related]

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  • 5. NMK-TD-100, a novel microtubule modulating agent, blocks mitosis and induces apoptosis in HeLa cells by binding to tubulin.
    Bhattacharya S, Kumar NM, Ganguli A, Tantak MP, Kumar D, Chakrabarti G.
    PLoS One; 2013 Feb 01; 8(10):e76286. PubMed ID: 24116100
    [Abstract] [Full Text] [Related]

  • 6. BZML, a novel colchicine binding site inhibitor, overcomes multidrug resistance in A549/Taxol cells by inhibiting P-gp function and inducing mitotic catastrophe.
    Bai Z, Gao M, Zhang H, Guan Q, Xu J, Li Y, Qi H, Li Z, Zuo D, Zhang W, Wu Y.
    Cancer Lett; 2017 Aug 28; 402():81-92. PubMed ID: 28576750
    [Abstract] [Full Text] [Related]

  • 7. 3-(3-Methoxyphenyl)-6-(3-amino-4-methoxyphenyl)-7H-[1,2,4] triazolo [3,4-b][1,3,4] thiadiazine, a novel tubulin inhibitor, evokes G2/M cell cycle arrest and apoptosis in SGC-7901 and HeLa cells.
    Liu Z, Lang B, Gao M, Chang X, Guan Q, Xu Q, Wu D, Li Z, Zuo D, Zhang W, Wu Y.
    J Cell Biochem; 2020 Mar 28; 121(3):2184-2196. PubMed ID: 31642107
    [Abstract] [Full Text] [Related]

  • 8. Targeting cellular microtubule by phytochemical apocynin exhibits autophagy-mediated apoptosis to inhibit lung carcinoma progression and tumorigenesis.
    Paul S, Chakrabarty S, Ghosh S, Nag D, Das A, Dastidar DG, Dasgupta M, Dutta N, Kumari M, Pal M, Chakrabarti G.
    Phytomedicine; 2020 Feb 28; 67():153152. PubMed ID: 31887479
    [Abstract] [Full Text] [Related]

  • 9. Methyl 5-[(1H-indol-3-yl)selanyl]-1H-benzoimidazol-2-ylcarbamate (M-24), a novel tubulin inhibitor, causes G2/M arrest and cell apoptosis by disrupting tubulin polymerization in human cervical and breast cancer cells.
    Zuo D, Jiang X, Han M, Shen J, Lang B, Guan Q, Bai Z, Han C, Li Z, Zhang W, Wu Y.
    Toxicol In Vitro; 2017 Aug 28; 42():139-149. PubMed ID: 28412508
    [Abstract] [Full Text] [Related]

  • 10. Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents.
    Zhou P, Liang Y, Zhang H, Jiang H, Feng K, Xu P, Wang J, Wang X, Ding K, Luo C, Liu M, Wang Y.
    Eur J Med Chem; 2018 Jan 20; 144():817-842. PubMed ID: 29306206
    [Abstract] [Full Text] [Related]

  • 11. SKLB060 Reversibly Binds to Colchicine Site of Tubulin and Possesses Efficacy in Multidrug-Resistant Cell Lines.
    Yan W, Yang T, Yang J, Wang T, Yu Y, Wang Y, Chen Q, Bai P, Li D, Ye H, Qiu Q, Zhou Y, Hu Y, Yang S, Wei Y, Li W, Chen L.
    Cell Physiol Biochem; 2018 Jan 20; 47(2):489-504. PubMed ID: 29794416
    [Abstract] [Full Text] [Related]

  • 12. Design, synthesis, and biological evaluation of novel benzodiazepine derivatives as anticancer agents through inhibition of tubulin polymerization in vitro and in vivo.
    Pang Y, Lin H, Ou C, Cao Y, An B, Yan J, Li X.
    Eur J Med Chem; 2019 Nov 15; 182():111670. PubMed ID: 31499359
    [Abstract] [Full Text] [Related]

  • 13. Development of triazolothiadiazine derivatives as highly potent tubulin polymerization inhibitors: Structure-activity relationship, in vitro and in vivo study.
    Ma W, Chen P, Huo X, Ma Y, Li Y, Diao P, Yang F, Zheng S, Hu M, You W, Zhao P.
    Eur J Med Chem; 2020 Dec 15; 208():112847. PubMed ID: 33022479
    [Abstract] [Full Text] [Related]

  • 14. DAT-230, a novel microtubule inhibitor, exhibits potent anti-tumor activity by inducing G2/M phase arrest, apoptosis in vitro and perfusion decrease in vivo to HT-1080.
    Qiao F, Zuo D, Shen X, Qi H, Wang H, Zhang W, Wu Y.
    Cancer Chemother Pharmacol; 2012 Aug 15; 70(2):259-70. PubMed ID: 22752214
    [Abstract] [Full Text] [Related]

  • 15. A novel synthetic compound exerts effective anti-tumour activity in vivo via the inhibition of tubulin polymerisation in A549 cells.
    Yan J, Pang Y, Sheng J, Wang Y, Chen J, Hu J, Huang L, Li X.
    Biochem Pharmacol; 2015 Sep 01; 97(1):51-61. PubMed ID: 26212540
    [Abstract] [Full Text] [Related]

  • 16. Deacetylisovaltratum disrupts microtubule dynamics and causes G2/M-phase arrest in human gastric cancer cells in vitro.
    Zhang D, Zhang B, Zhou LX, Zhao J, Yan YY, Li YL, Zeng JM, Wang LL, Yang B, Lin NM.
    Acta Pharmacol Sin; 2016 Dec 01; 37(12):1597-1605. PubMed ID: 27665846
    [Abstract] [Full Text] [Related]

  • 17. Design, synthesis and biological evaluation of 1, 4-dihydro indeno[1,2-c] pyrazole linked oxindole analogues as potential anticancer agents targeting tubulin and inducing p53 dependent apoptosis.
    Khan I, Garikapati KR, Shaik AB, Makani VKK, Rahim A, Shareef MA, Reddy VG, Pal-Bhadra M, Kamal A, Kumar CG.
    Eur J Med Chem; 2018 Jan 20; 144():104-115. PubMed ID: 29268127
    [Abstract] [Full Text] [Related]

  • 18. Pyrrolotetrazinones deazaanalogues of temozolomide induce apoptosis in Jurkat cell line: involvement of tubulin polymerization inhibition.
    Viola G, Cecconet L, Leszl A, Basso G, Brun P, Salvador A, Dall'Acqua F, Diana P, Barraja P, Cirrincione G.
    Cancer Chemother Pharmacol; 2009 Nov 20; 64(6):1235-51. PubMed ID: 19363609
    [Abstract] [Full Text] [Related]

  • 19. Mitotic cell death induction by targeting the mitotic spindle with tubulin-inhibitory indole derivative molecules.
    Di Cesare E, Verrico A, Miele A, Giubettini M, Rovella P, Coluccia A, Famiglini V, La Regina G, Cundari E, Silvestri R, Lavia P.
    Oncotarget; 2017 Mar 21; 8(12):19738-19759. PubMed ID: 28160569
    [Abstract] [Full Text] [Related]

  • 20. Resveratrol analog (Z)-3,5,4'-trimethoxystilbene is a potent anti-mitotic drug inhibiting tubulin polymerization.
    Schneider Y, Chabert P, Stutzmann J, Coelho D, Fougerousse A, Gossé F, Launay JF, Brouillard R, Raul F.
    Int J Cancer; 2003 Nov 01; 107(2):189-96. PubMed ID: 12949793
    [Abstract] [Full Text] [Related]

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