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621 related items for PubMed ID: 27756877

  • 1. Marsdenia tenacissimae extraction (MTE) inhibits the proliferation and induces the apoptosis of human acute T cell leukemia cells through inactivating PI3K/AKT/mTOR signaling pathway via PTEN enhancement.
    Wang Y, Chen B, Wang Z, Zhang W, Hao K, Chen Y, Li K, Wang T, Xie Y, Huang Z, Tong X.
    Oncotarget; 2016 Dec 13; 7(50):82851-82863. PubMed ID: 27756877
    [Abstract] [Full Text] [Related]

  • 2. Marsdeniae tenacissimae extract (MTE) suppresses cell proliferation by attenuating VEGF/VEGFR2 interactions and promotes apoptosis through regulating PKC pathway in human umbilical vein endothelial cells.
    Chen BY, Chen D, Lyu JX, Li KQ, Jiang MM, Zeng JJ, He XJ, Hao K, Tao HQ, Mou XZ, Ying YM, Zhang W, Zhu MH, Wang Z.
    Chin J Nat Med; 2016 Dec 13; 14(12):922-930. PubMed ID: 28262119
    [Abstract] [Full Text] [Related]

  • 3. Marsdenia Tenacissima Extract Inhibits Proliferation and Promotes Apoptosis in Human Ovarian Cancer Cells.
    Zhang Y, Zhang Y.
    Med Sci Monit; 2018 Sep 09; 24():6289-6297. PubMed ID: 30196309
    [Abstract] [Full Text] [Related]

  • 4. PI3K/AKT/mTOR signaling is involved in (-)-epigallocatechin-3-gallate-induced apoptosis of human pancreatic carcinoma cells.
    Liu S, Wang XJ, Liu Y, Cui YF.
    Am J Chin Med; 2013 Sep 09; 41(3):629-42. PubMed ID: 23711146
    [Abstract] [Full Text] [Related]

  • 5. The Critical Role of PTEN/PI3K/AKT Signaling Pathway in Shikonin-Induced Apoptosis and Proliferation Inhibition of Chronic Myeloid Leukemia.
    Chen Y, Wang T, Du J, Li Y, Wang X, Zhou Y, Yu X, Fan W, Zhu Q, Tong X, Wang Y.
    Cell Physiol Biochem; 2018 Sep 09; 47(3):981-993. PubMed ID: 29843123
    [Abstract] [Full Text] [Related]

  • 6. Triple Akt inhibition as a new therapeutic strategy in T-cell acute lymphoblastic leukemia.
    Cani A, Simioni C, Martelli AM, Zauli G, Tabellini G, Ultimo S, McCubrey JA, Capitani S, Neri LM.
    Oncotarget; 2015 Mar 30; 6(9):6597-610. PubMed ID: 25788264
    [Abstract] [Full Text] [Related]

  • 7. Anti-proliferative effect of RCE-4 from Reineckia carnea on human cervical cancer HeLa cells by inhibiting the PI3K/Akt/mTOR signaling pathway and NF-κB activation.
    Bai C, Yang X, Zou K, He H, Wang J, Qin H, Yu X, Liu C, Zheng J, Cheng F, Chen J.
    Naunyn Schmiedebergs Arch Pharmacol; 2016 Jun 30; 389(6):573-84. PubMed ID: 26935715
    [Abstract] [Full Text] [Related]

  • 8. Apoptosis induced by the methanol extract of Salvia miltiorrhiza Bunge in non-small cell lung cancer through PTEN-mediated inhibition of PI3K/Akt pathway.
    Ye YT, Zhong W, Sun P, Wang D, Wang C, Hu LM, Qian JQ.
    J Ethnopharmacol; 2017 Mar 22; 200():107-116. PubMed ID: 28088493
    [Abstract] [Full Text] [Related]

  • 9. Marsdenia tenacissima extract restored gefitinib sensitivity in resistant non-small cell lung cancer cells.
    Han SY, Zhao MB, Zhuang GB, Li PP.
    Lung Cancer; 2012 Jan 22; 75(1):30-7. PubMed ID: 21757251
    [Abstract] [Full Text] [Related]

  • 10. Healthy CD4+ T lymphocytes are not affected by targeted therapies against the PI3K/Akt/mTOR pathway in T-cell acute lymphoblastic leukemia.
    Alameen AA, Simioni C, Martelli AM, Zauli G, Ultimo S, McCubrey JA, Gonelli A, Marisi G, Ulivi P, Capitani S, Neri LM.
    Oncotarget; 2016 Aug 23; 7(34):55690-55703. PubMed ID: 27494886
    [Abstract] [Full Text] [Related]

  • 11. PDB-1 from Potentilla discolor Bunge induces apoptosis and autophagy by downregulating the PI3K/Akt/mTOR signaling pathway in A549 cells.
    Zhang RR, Meng NN, Liu C, Li KL, Wang MX, Lv ZB, Chen SY, Guo X, Wang XK, Wang Q, Sun JY.
    Biomed Pharmacother; 2020 Sep 23; 129():110378. PubMed ID: 32544818
    [Abstract] [Full Text] [Related]

  • 12. Resveratrol induces apoptosis and autophagy in T-cell acute lymphoblastic leukemia cells by inhibiting Akt/mTOR and activating p38-MAPK.
    Ge J, Liu Y, Li Q, Guo X, Gu L, Ma ZG, Zhu YP.
    Biomed Environ Sci; 2013 Nov 23; 26(11):902-11. PubMed ID: 24331535
    [Abstract] [Full Text] [Related]

  • 13. The dual specificity PI3K/mTOR inhibitor PKI-587 displays efficacy against T-cell acute lymphoblastic leukemia (T-ALL).
    Gazi M, Moharram SA, Marhäll A, Kazi JU.
    Cancer Lett; 2017 Apr 28; 392():9-16. PubMed ID: 28159681
    [Abstract] [Full Text] [Related]

  • 14. Tetrandrine and cepharanthine induce apoptosis through caspase cascade regulation, cell cycle arrest, MAPK activation and PI3K/Akt/mTOR signal modification in glucocorticoid resistant human leukemia Jurkat T cells.
    Xu W, Wang X, Tu Y, Masaki H, Tanaka S, Onda K, Sugiyama K, Yamada H, Hirano T.
    Chem Biol Interact; 2019 Sep 01; 310():108726. PubMed ID: 31255635
    [Abstract] [Full Text] [Related]

  • 15. L-securinine induces apoptosis in the human promyelocytic leukemia cell line HL-60 and influences the expression of genes involved in the PI3K/AKT/mTOR signaling pathway.
    Han S, Zhang G, Li M, Chen D, Wang Y, Ye W, Ji Z.
    Oncol Rep; 2014 May 01; 31(5):2245-51. PubMed ID: 24676995
    [Abstract] [Full Text] [Related]

  • 16. Enhancement of gefitinib-induced growth inhibition by Marsdenia tenacissima extract in non-small cell lung cancer cells expressing wild or mutant EGFR.
    Han SY, Ding HR, Zhao W, Teng F, Li PP.
    BMC Complement Altern Med; 2014 May 22; 14():165. PubMed ID: 24884778
    [Abstract] [Full Text] [Related]

  • 17. A new discovery: Total Bupleurum saponin extracts can inhibit the proliferation and induce apoptosis of colon cancer cells by regulating the PI3K/Akt/mTOR pathway.
    Zhang X, Liu Z, Chen S, Li H, Dong L, Fu X.
    J Ethnopharmacol; 2022 Jan 30; 283():114742. PubMed ID: 34655668
    [Abstract] [Full Text] [Related]

  • 18. Jolkinolide B induces apoptosis in MCF-7 cells through inhibition of the PI3K/Akt/mTOR signaling pathway.
    Xu HY, Chen ZW, Hou JC, Du FX, Liu JC.
    Oncol Rep; 2013 Jan 30; 29(1):212-8. PubMed ID: 23129237
    [Abstract] [Full Text] [Related]

  • 19. Hedyotis diffusa Willd inhibits proliferation and induces apoptosis of 5‑FU resistant colorectal cancer cells by regulating the PI3K/AKT signaling pathway.
    Li Q, Lai Z, Yan Z, Peng J, Jin Y, Wei L, Lin J.
    Mol Med Rep; 2018 Jan 30; 17(1):358-365. PubMed ID: 29115462
    [Abstract] [Full Text] [Related]

  • 20. Ursolic acid-induced apoptosis in K562 cells involving upregulation of PTEN gene expression and inactivation of the PI3K/Akt pathway.
    Wu B, Wang X, Chi ZF, Hu R, Zhang R, Yang W, Liu ZG.
    Arch Pharm Res; 2012 Mar 30; 35(3):543-8. PubMed ID: 22477202
    [Abstract] [Full Text] [Related]

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