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Journal Abstract Search

324 related items for PubMed ID: 27760414

  • 1. Junctophilin-2 gene therapy rescues heart failure by normalizing RyR2-mediated Ca2+ release.
    Reynolds JO, Quick AP, Wang Q, Beavers DL, Philippen LE, Showell J, Barreto-Torres G, Thuerauf DJ, Doroudgar S, Glembotski CC, Wehrens XH.
    Int J Cardiol; 2016 Dec 15; 225():371-380. PubMed ID: 27760414
    [Abstract] [Full Text] [Related]

  • 2. Reduced junctional Na+/Ca2+-exchanger activity contributes to sarcoplasmic reticulum Ca2+ leak in junctophilin-2-deficient mice.
    Wang W, Landstrom AP, Wang Q, Munro ML, Beavers D, Ackerman MJ, Soeller C, Wehrens XH.
    Am J Physiol Heart Circ Physiol; 2014 Nov 01; 307(9):H1317-26. PubMed ID: 25193470
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  • 3. SPEG (Striated Muscle Preferentially Expressed Protein Kinase) Is Essential for Cardiac Function by Regulating Junctional Membrane Complex Activity.
    Quick AP, Wang Q, Philippen LE, Barreto-Torres G, Chiang DY, Beavers D, Wang G, Khalid M, Reynolds JO, Campbell HM, Showell J, McCauley MD, Scholten A, Wehrens XH.
    Circ Res; 2017 Jan 06; 120(1):110-119. PubMed ID: 27729468
    [Abstract] [Full Text] [Related]

  • 4. Interaction of the Joining Region in Junctophilin-2 With the L-Type Ca2+ Channel Is Pivotal for Cardiac Dyad Assembly and Intracellular Ca2+ Dynamics.
    Gross P, Johnson J, Romero CM, Eaton DM, Poulet C, Sanchez-Alonso J, Lucarelli C, Ross J, Gibb AA, Garbincius JF, Lambert J, Varol E, Yang Y, Wallner M, Feldsott EA, Kubo H, Berretta RM, Yu D, Rizzo V, Elrod J, Sabri A, Gorelik J, Chen X, Houser SR.
    Circ Res; 2021 Jan 08; 128(1):92-114. PubMed ID: 33092464
    [Abstract] [Full Text] [Related]

  • 5. Mutation E169K in junctophilin-2 causes atrial fibrillation due to impaired RyR2 stabilization.
    Beavers DL, Wang W, Ather S, Voigt N, Garbino A, Dixit SS, Landstrom AP, Li N, Wang Q, Olivotto I, Dobrev D, Ackerman MJ, Wehrens XHT.
    J Am Coll Cardiol; 2013 Nov 19; 62(21):2010-9. PubMed ID: 23973696
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  • 9. Microtubule-mediated defects in junctophilin-2 trafficking contribute to myocyte transverse-tubule remodeling and Ca2+ handling dysfunction in heart failure.
    Zhang C, Chen B, Guo A, Zhu Y, Miller JD, Gao S, Yuan C, Kutschke W, Zimmerman K, Weiss RM, Wehrens XH, Hong J, Johnson FL, Santana LF, Anderson ME, Song LS.
    Circulation; 2014 Apr 29; 129(17):1742-50. PubMed ID: 24519927
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  • 10. Subclinical abnormalities in sarcoplasmic reticulum Ca(2+) release promote eccentric myocardial remodeling and pump failure death in response to pressure overload.
    Sedej S, Schmidt A, Denegri M, Walther S, Matovina M, Arnstein G, Gutschi EM, Windhager I, Ljubojević S, Negri S, Heinzel FR, Bisping E, Vos MA, Napolitano C, Priori SG, Kockskämper J, Pieske B.
    J Am Coll Cardiol; 2014 Apr 22; 63(15):1569-79. PubMed ID: 24315909
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  • 11. Junctophilin-2 expression silencing causes cardiocyte hypertrophy and abnormal intracellular calcium-handling.
    Landstrom AP, Kellen CA, Dixit SS, van Oort RJ, Garbino A, Weisleder N, Ma J, Wehrens XH, Ackerman MJ.
    Circ Heart Fail; 2011 Mar 22; 4(2):214-23. PubMed ID: 21216834
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  • 13. Caveolin 3-dependent loss of t-tubular ICa during hypertrophy and heart failure in mice.
    Bryant SM, Kong CHT, Watson JJ, Gadeberg HC, James AF, Cannell MB, Orchard CH.
    Exp Physiol; 2018 May 01; 103(5):652-665. PubMed ID: 29473235
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  • 14. SERCA2a ameliorates cardiomyocyte T-tubule remodeling via the calpain/JPH2 pathway to improve cardiac function in myocardial ischemia/reperfusion mice.
    Wang S, Zhou Y, Luo Y, Kan R, Chen J, Xuan H, Wang C, Chen J, Xu T, Li D.
    Sci Rep; 2021 Jan 21; 11(1):2037. PubMed ID: 33479390
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  • 16. Junctophilin-2 is necessary for T-tubule maturation during mouse heart development.
    Reynolds JO, Chiang DY, Wang W, Beavers DL, Dixit SS, Skapura DG, Landstrom AP, Song LS, Ackerman MJ, Wehrens XH.
    Cardiovasc Res; 2013 Oct 01; 100(1):44-53. PubMed ID: 23715556
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  • 18. Triadin overexpression stimulates excitation-contraction coupling and increases predisposition to cellular arrhythmia in cardiac myocytes.
    Terentyev D, Cala SE, Houle TD, Viatchenko-Karpinski S, Gyorke I, Terentyeva R, Williams SC, Gyorke S.
    Circ Res; 2005 Apr 01; 96(6):651-8. PubMed ID: 15731460
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  • 20. Right-sided heart failure is also associated with transverse tubule remodeling in the left ventricle.
    Howe K, Ross JM, Loiselle DS, Han JC, Crossman DJ.
    Am J Physiol Heart Circ Physiol; 2021 Nov 01; 321(5):H940-H947. PubMed ID: 34559582
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