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Journal Abstract Search

453 related items for PubMed ID: 27760840

  • 1. mTORC1 signalling and eIF4E/4E-BP1 translation initiation factor stoichiometry influence recombinant protein productivity from GS-CHOK1 cells.
    Jossé L, Xie J, Proud CG, Smales CM.
    Biochem J; 2016 Dec 15; 473(24):4651-4664. PubMed ID: 27760840
    [Abstract] [Full Text] [Related]

  • 2. Chemical manipulation of the mTORC1 pathway in industrially relevant CHOK1 cells enhances production of therapeutic proteins.
    Dadehbeigi N, Dickson AJ.
    Biotechnol J; 2015 Jul 15; 10(7):1041-50. PubMed ID: 26059164
    [Abstract] [Full Text] [Related]

  • 3. mTORC1 drives HIF-1α and VEGF-A signalling via multiple mechanisms involving 4E-BP1, S6K1 and STAT3.
    Dodd KM, Yang J, Shen MH, Sampson JR, Tee AR.
    Oncogene; 2015 Apr 23; 34(17):2239-50. PubMed ID: 24931163
    [Abstract] [Full Text] [Related]

  • 4. Phosphatidylinositol-3 kinase-dependent translational regulation of Id1 involves the PPM1G phosphatase.
    Xu K, Wang L, Feng W, Feng Y, Shu HK.
    Oncogene; 2016 Nov 03; 35(44):5807-5816. PubMed ID: 27065332
    [Abstract] [Full Text] [Related]

  • 5. Regulated in development and DNA damage 1 is necessary for hyperglycemia-induced vascular endothelial growth factor expression in the retina of diabetic rodents.
    Dennis MD, Kimball SR, Fort PE, Jefferson LS.
    J Biol Chem; 2015 Feb 06; 290(6):3865-74. PubMed ID: 25548280
    [Abstract] [Full Text] [Related]

  • 6. 4E-BP1, a multifactor regulated multifunctional protein.
    Qin X, Jiang B, Zhang Y.
    Cell Cycle; 2016 Feb 06; 15(6):781-6. PubMed ID: 26901143
    [Abstract] [Full Text] [Related]

  • 7. The dynamic mechanism of 4E-BP1 recognition and phosphorylation by mTORC1.
    Böhm R, Imseng S, Jakob RP, Hall MN, Maier T, Hiller S.
    Mol Cell; 2021 Jun 03; 81(11):2403-2416.e5. PubMed ID: 33852892
    [Abstract] [Full Text] [Related]

  • 8. AKT inhibition overcomes rapamycin resistance by enhancing the repressive function of PRAS40 on mTORC1/4E-BP1 axis.
    Mi W, Ye Q, Liu S, She QB.
    Oncotarget; 2015 Jun 10; 6(16):13962-77. PubMed ID: 25961827
    [Abstract] [Full Text] [Related]

  • 9. Protein phosphatase PPM1G regulates protein translation and cell growth by dephosphorylating 4E binding protein 1 (4E-BP1).
    Liu J, Stevens PD, Eshleman NE, Gao T.
    J Biol Chem; 2013 Aug 09; 288(32):23225-33. PubMed ID: 23814053
    [Abstract] [Full Text] [Related]

  • 10. Growth-factor dependent expression of the translationally controlled tumour protein TCTP is regulated through the PI3-K/Akt/mTORC1 signalling pathway.
    Bommer UA, Iadevaia V, Chen J, Knoch B, Engel M, Proud CG.
    Cell Signal; 2015 Aug 09; 27(8):1557-68. PubMed ID: 25936523
    [Abstract] [Full Text] [Related]

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  • 12. Reappraisal to the study of 4E-BP1 as an mTOR substrate - A normative critique.
    Batool A, Aashaq S, Andrabi KI.
    Eur J Cell Biol; 2017 Jun 09; 96(4):325-336. PubMed ID: 28427795
    [Abstract] [Full Text] [Related]

  • 13. La-related Protein 1 (LARP1) Represses Terminal Oligopyrimidine (TOP) mRNA Translation Downstream of mTOR Complex 1 (mTORC1).
    Fonseca BD, Zakaria C, Jia JJ, Graber TE, Svitkin Y, Tahmasebi S, Healy D, Hoang HD, Jensen JM, Diao IT, Lussier A, Dajadian C, Padmanabhan N, Wang W, Matta-Camacho E, Hearnden J, Smith EM, Tsukumo Y, Yanagiya A, Morita M, Petroulakis E, González JL, Hernández G, Alain T, Damgaard CK.
    J Biol Chem; 2015 Jun 26; 290(26):15996-6020. PubMed ID: 25940091
    [Abstract] [Full Text] [Related]

  • 14. Reciprocal regulation of mTOR complexes in pancreatic islets from humans with type 2 diabetes.
    Yuan T, Rafizadeh S, Gorrepati KD, Lupse B, Oberholzer J, Maedler K, Ardestani A.
    Diabetologia; 2017 Apr 26; 60(4):668-678. PubMed ID: 28004151
    [Abstract] [Full Text] [Related]

  • 15. Phosphorylation dynamics of eukaryotic initiation factor 4E binding protein 1 (4E-BP1) is discordant with its potential to interact with eukaryotic initiation factor 4E (eIF4E).
    Showkat M, Beigh MA, Bhat BB, Batool A, Andrabi KI.
    Cell Signal; 2014 Oct 26; 26(10):2117-21. PubMed ID: 24975846
    [Abstract] [Full Text] [Related]

  • 16. Hydrogen peroxide impairs insulin-stimulated assembly of mTORC1.
    Zhang L, Kimball SR, Jefferson LS, Shenberger JS.
    Free Radic Biol Med; 2009 Jun 01; 46(11):1500-9. PubMed ID: 19281842
    [Abstract] [Full Text] [Related]

  • 17. Characterization of the Raptor/4E-BP1 interaction by chemical cross-linking coupled with mass spectrometry analysis.
    Coffman K, Yang B, Lu J, Tetlow AL, Pelliccio E, Lu S, Guo DC, Tang C, Dong MQ, Tamanoi F.
    J Biol Chem; 2014 Feb 21; 289(8):4723-34. PubMed ID: 24403073
    [Abstract] [Full Text] [Related]

  • 18. Eukaryotic Initiation Factor 4E (eIF4E) sequestration mediates 4E-BP1 response to rapamycin.
    Batool A, Majeed ST, Aashaq S, Majeed R, Shah G, Nazir N, Andrabi KI.
    Int J Biol Macromol; 2019 Mar 15; 125():651-659. PubMed ID: 30552925
    [Abstract] [Full Text] [Related]

  • 19. Ubiquilin-mediated Small Molecule Inhibition of Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling.
    Coffey RT, Shi Y, Long MJ, Marr MT, Hedstrom L.
    J Biol Chem; 2016 Mar 04; 291(10):5221-33. PubMed ID: 26740621
    [Abstract] [Full Text] [Related]

  • 20. Both mTORC1 and mTORC2 are involved in the regulation of cell adhesion.
    Chen L, Xu B, Liu L, Liu C, Luo Y, Chen X, Barzegar M, Chung J, Huang S.
    Oncotarget; 2015 Mar 30; 6(9):7136-50. PubMed ID: 25762619
    [Abstract] [Full Text] [Related]

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