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Journal Abstract Search

382 related items for PubMed ID: 27777067

  • 1. Securinine disturbs redox homeostasis and elicits oxidative stress-mediated apoptosis via targeting thioredoxin reductase.
    Zhang J, Yao J, Peng S, Li X, Fang J.
    Biochim Biophys Acta Mol Basis Dis; 2017 Jan; 1863(1):129-138. PubMed ID: 27777067
    [Abstract] [Full Text] [Related]

  • 2. Inhibition of thioredoxin reductase by alantolactone prompts oxidative stress-mediated apoptosis of HeLa cells.
    Zhang J, Li Y, Duan D, Yao J, Gao K, Fang J.
    Biochem Pharmacol; 2016 Feb 15; 102():34-44. PubMed ID: 26686580
    [Abstract] [Full Text] [Related]

  • 3. Xanthatin Promotes Apoptosis via Inhibiting Thioredoxin Reductase and Eliciting Oxidative Stress.
    Liu R, Shi D, Zhang J, Li X, Han X, Yao X, Fang J.
    Mol Pharm; 2018 Aug 06; 15(8):3285-3296. PubMed ID: 29939757
    [Abstract] [Full Text] [Related]

  • 4. Promotion of HeLa cells apoptosis by cynaropicrin involving inhibition of thioredoxin reductase and induction of oxidative stress.
    Liu T, Zhang J, Han X, Xu J, Wu Y, Fang J.
    Free Radic Biol Med; 2019 May 01; 135():216-226. PubMed ID: 30880248
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and biological evaluation of new securinine analogues as potential anticancer agents.
    Perez M, Ayad T, Maillos P, Poughon V, Fahy J, Ratovelomanana-Vidal V.
    Eur J Med Chem; 2016 Feb 15; 109():287-93. PubMed ID: 26793989
    [Abstract] [Full Text] [Related]

  • 6. Onopordopicrin from the new genus Shangwua as a novel thioredoxin reductase inhibitor to induce oxidative stress-mediated tumor cell apoptosis.
    Zhang J, Zheng ZQ, Xu Q, Li Y, Gao K, Fang J.
    J Enzyme Inhib Med Chem; 2021 Dec 15; 36(1):790-801. PubMed ID: 33733960
    [Abstract] [Full Text] [Related]

  • 7. Targeting thioredoxin reductase by deoxyelephantopin from Elephantopus scaber triggers cancer cell apoptosis.
    Duan D, Wang Y, Pan D, Wang L, Xiao J, Song P, Jin X, Wang X.
    Arch Biochem Biophys; 2021 Oct 30; 711():109028. PubMed ID: 34509463
    [Abstract] [Full Text] [Related]

  • 8. Flueggeacosines A-C, Dimeric Securinine-Type Alkaloid Analogues with Neuronal Differentiation Activity from Flueggea suffruticosa.
    Wu ZL, Huang XJ, Xu MT, Ma X, Li L, Shi L, Wang WJ, Jiang RW, Ye WC, Wang Y.
    Org Lett; 2018 Dec 07; 20(23):7703-7707. PubMed ID: 30484660
    [Abstract] [Full Text] [Related]

  • 9. Synthesis of naphthazarin derivatives and identification of novel thioredoxin reductase inhibitor as potential anticancer agent.
    Zhang J, Liu Y, Shi D, Hu G, Zhang B, Li X, Liu R, Han X, Yao X, Fang J.
    Eur J Med Chem; 2017 Nov 10; 140():435-447. PubMed ID: 28987605
    [Abstract] [Full Text] [Related]

  • 10. EM23, a natural sesquiterpene lactone, targets thioredoxin reductase to activate JNK and cell death pathways in human cervical cancer cells.
    Shao FY, Wang S, Li HY, Chen WB, Wang GC, Ma DL, Wong NS, Xiao H, Liu QY, Zhou GX, Li YL, Li MM, Wang YF, Liu Z.
    Oncotarget; 2016 Feb 09; 7(6):6790-808. PubMed ID: 26758418
    [Abstract] [Full Text] [Related]

  • 11. The Securinega alkaloids.
    Chirkin E, Atkatlian W, Porée FH.
    Alkaloids Chem Biol; 2015 Feb 09; 74():1-120. PubMed ID: 25845059
    [Abstract] [Full Text] [Related]

  • 12. Targeting the Thioredoxin System for Cancer Therapy.
    Zhang J, Li X, Han X, Liu R, Fang J.
    Trends Pharmacol Sci; 2017 Sep 09; 38(9):794-808. PubMed ID: 28648527
    [Abstract] [Full Text] [Related]

  • 13. Securinine from Phyllanthus glaucus Induces Cell Cycle Arrest and Apoptosis in Human Cervical Cancer HeLa Cells.
    Stefanowicz-Hajduk J, Sparzak-Stefanowska B, Krauze-Baranowska M, Ochocka JR.
    PLoS One; 2016 Sep 09; 11(10):e0165372. PubMed ID: 27792748
    [Abstract] [Full Text] [Related]

  • 14. Dithiaarsanes induce oxidative stress-mediated apoptosis in HL-60 cells by selectively targeting thioredoxin reductase.
    Liu Y, Duan D, Yao J, Zhang B, Peng S, Ma H, Song Y, Fang J.
    J Med Chem; 2014 Jun 26; 57(12):5203-11. PubMed ID: 24867309
    [Abstract] [Full Text] [Related]

  • 15. Targeting Thioredoxin Reductase by Parthenolide Contributes to Inducing Apoptosis of HeLa Cells.
    Duan D, Zhang J, Yao J, Liu Y, Fang J.
    J Biol Chem; 2016 May 06; 291(19):10021-31. PubMed ID: 27002142
    [Abstract] [Full Text] [Related]

  • 16. Daucosterol disturbs redox homeostasis and elicits oxidative-stress mediated apoptosis in A549 cells via targeting thioredoxin reductase by a p53 dependent mechanism.
    Rajavel T, Banu Priya G, Suryanarayanan V, Singh SK, Pandima Devi K.
    Eur J Pharmacol; 2019 Jul 15; 855():112-123. PubMed ID: 31059712
    [Abstract] [Full Text] [Related]

  • 17. Gambogic acid induces apoptosis in hepatocellular carcinoma SMMC-7721 cells by targeting cytosolic thioredoxin reductase.
    Duan D, Zhang B, Yao J, Liu Y, Sun J, Ge C, Peng S, Fang J.
    Free Radic Biol Med; 2014 Apr 15; 69():15-25. PubMed ID: 24407164
    [Abstract] [Full Text] [Related]

  • 18. Targeting thioredoxin reductase by plumbagin contributes to inducing apoptosis of HL-60 cells.
    Zhang J, Peng S, Li X, Liu R, Han X, Fang J.
    Arch Biochem Biophys; 2017 Apr 01; 619():16-26. PubMed ID: 28249720
    [Abstract] [Full Text] [Related]

  • 19. L-securinine induces apoptosis in the human promyelocytic leukemia cell line HL-60 and influences the expression of genes involved in the PI3K/AKT/mTOR signaling pathway.
    Han S, Zhang G, Li M, Chen D, Wang Y, Ye W, Ji Z.
    Oncol Rep; 2014 May 01; 31(5):2245-51. PubMed ID: 24676995
    [Abstract] [Full Text] [Related]

  • 20. A diterpenoid derivate compound targets selenocysteine of thioredoxin reductases and induces Bax/Bak-independent apoptosis.
    Liu J, Mu C, Yue W, Li J, Ma B, Zhao L, Liu L, Chen Q, Yan C, Liu H, Hao X, Zhu Y.
    Free Radic Biol Med; 2013 Oct 01; 63():485-94. PubMed ID: 23732520
    [Abstract] [Full Text] [Related]

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