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216 related items for PubMed ID: 27787559

  • 1. Identification and Functional Assessment of Age-Dependent Truncations to Cx46 and Cx50 in the Human Lens.
    Slavi N, Wang Z, Harvey L, Schey KL, Srinivas M.
    Invest Ophthalmol Vis Sci; 2016 Oct 01; 57(13):5714-5722. PubMed ID: 27787559
    [Abstract] [Full Text] [Related]

  • 2. Connexin 46 (cx46) gap junctions provide a pathway for the delivery of glutathione to the lens nucleus.
    Slavi N, Rubinos C, Li L, Sellitto C, White TW, Mathias R, Srinivas M.
    J Biol Chem; 2014 Nov 21; 289(47):32694-702. PubMed ID: 25294879
    [Abstract] [Full Text] [Related]

  • 3. Aging-dependent loss of GAP junction proteins Cx46 and Cx50 in the fiber cells of human and mouse lenses accounts for the diminished coupling conductance.
    Gong XD, Wang Y, Hu XB, Zheng SY, Fu JL, Nie Q, Wang L, Hou M, Xiang JW, Xiao Y, Gao Q, Bai YY, Liu YZ, Li DW.
    Aging (Albany NY); 2021 Jul 04; 13(13):17568-17591. PubMed ID: 34226295
    [Abstract] [Full Text] [Related]

  • 4. Developmental truncations of connexin 50 by caspases adaptively regulate gap junctions/hemichannels and protect lens cells against ultraviolet radiation.
    Wang K, Gu S, Yin X, Weintraub ST, Hua Z, Jiang JX.
    J Biol Chem; 2012 May 04; 287(19):15786-97. PubMed ID: 22418432
    [Abstract] [Full Text] [Related]

  • 5. Human Cx50 Isoleucine177 prevents heterotypic docking and formation of functional gap junction channels with Cx43.
    Wong RS, Chen H, Li YX, Esseltine JL, Stathopulos PB, Bai D.
    Am J Physiol Cell Physiol; 2024 Feb 01; 326(2):C414-C428. PubMed ID: 38145302
    [Abstract] [Full Text] [Related]

  • 6. The cataract-inducing S50P mutation in Cx50 dominantly alters the channel gating of wild-type lens connexins.
    DeRosa AM, Xia CH, Gong X, White TW.
    J Cell Sci; 2007 Dec 01; 120(Pt 23):4107-16. PubMed ID: 18003700
    [Abstract] [Full Text] [Related]

  • 7. Dominant cataracts result from incongruous mixing of wild-type lens connexins.
    Martinez-Wittinghan FJ, Sellitto C, Li L, Gong X, Brink PR, Mathias RT, White TW.
    J Cell Biol; 2003 Jun 09; 161(5):969-78. PubMed ID: 12782682
    [Abstract] [Full Text] [Related]

  • 8. The Hydrophobic Residues in Amino Terminal Domains of Cx46 and Cx50 Are Important for Their Gap Junction Channel Ion Permeation and Gating.
    Jaradat R, Li X, Chen H, Stathopulos PB, Bai D.
    Int J Mol Sci; 2022 Oct 01; 23(19):. PubMed ID: 36232905
    [Abstract] [Full Text] [Related]

  • 9. Cataracts and microphthalmia caused by a Gja8 mutation in extracellular loop 2.
    Xia CH, Chang B, Derosa AM, Cheng C, White TW, Gong X.
    PLoS One; 2012 Oct 01; 7(12):e52894. PubMed ID: 23300808
    [Abstract] [Full Text] [Related]

  • 10. Properties of gap junction channels formed by Cx46 alone and in combination with Cx50.
    Hopperstad MG, Srinivas M, Spray DC.
    Biophys J; 2000 Oct 01; 79(4):1954-66. PubMed ID: 11023900
    [Abstract] [Full Text] [Related]

  • 11. Selective interactions among the multiple connexin proteins expressed in the vertebrate lens: the second extracellular domain is a determinant of compatibility between connexins.
    White TW, Bruzzone R, Wolfram S, Paul DL, Goodenough DA.
    J Cell Biol; 1994 May 01; 125(4):879-92. PubMed ID: 8188753
    [Abstract] [Full Text] [Related]

  • 12. Connexin 46 and connexin 50 gap junction channel properties are shaped by structural and dynamic features of their N-terminal domains.
    Yue B, Haddad BG, Khan U, Chen H, Atalla M, Zhang Z, Zuckerman DM, Reichow SL, Bai D.
    J Physiol; 2021 Jul 01; 599(13):3313-3335. PubMed ID: 33876426
    [Abstract] [Full Text] [Related]

  • 13. Knock-in of Cx46 partially rescues fiber defects in lenses lacking Cx50.
    Wang E, Geng A, Seo R, Maniar A, Gong X.
    Mol Vis; 2017 Jul 01; 23():160-170. PubMed ID: 28458505
    [Abstract] [Full Text] [Related]

  • 14. Cx46 hemichannels contribute to the sodium leak conductance in lens fiber cells.
    Ebihara L, Korzyukov Y, Kothari S, Tong JJ.
    Am J Physiol Cell Physiol; 2014 Mar 01; 306(5):C506-13. PubMed ID: 24380846
    [Abstract] [Full Text] [Related]

  • 15. Regulation of lens cell-to-cell communication by activation of PKCgamma and disassembly of Cx50 channels.
    Zampighi GA, Planells AM, Lin D, Takemoto D.
    Invest Ophthalmol Vis Sci; 2005 Sep 01; 46(9):3247-55. PubMed ID: 16123426
    [Abstract] [Full Text] [Related]

  • 16. Connections between connexins, calcium, and cataracts in the lens.
    Gao J, Sun X, Martinez-Wittinghan FJ, Gong X, White TW, Mathias RT.
    J Gen Physiol; 2004 Oct 01; 124(4):289-300. PubMed ID: 15452195
    [Abstract] [Full Text] [Related]

  • 17. Optimal lens epithelial cell proliferation is dependent on the connexin isoform providing gap junctional coupling.
    White TW, Gao Y, Li L, Sellitto C, Srinivas M.
    Invest Ophthalmol Vis Sci; 2007 Dec 01; 48(12):5630-7. PubMed ID: 18055813
    [Abstract] [Full Text] [Related]

  • 18. Connexin 46 and connexin 50 in selenite cataract.
    Fleschner CR.
    Ophthalmic Res; 2006 Dec 01; 38(1):24-8. PubMed ID: 16192745
    [Abstract] [Full Text] [Related]

  • 19. Functional effects of Cx50 mutations associated with congenital cataracts.
    Rubinos C, Villone K, Mhaske PV, White TW, Srinivas M.
    Am J Physiol Cell Physiol; 2014 Feb 01; 306(3):C212-20. PubMed ID: 24005045
    [Abstract] [Full Text] [Related]

  • 20. Charged multivesicular body protein 4b forms complexes with gap junction proteins during lens fiber cell differentiation.
    Zhou Y, Bennett TM, White TW, Shiels A.
    FASEB J; 2023 Apr 01; 37(4):e22801. PubMed ID: 36880430
    [Abstract] [Full Text] [Related]

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