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Journal Abstract Search

329 related items for PubMed ID: 27797456

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  • 5. Insight into the structural mechanism for PKBα allosteric inhibition by molecular dynamics simulations and free energy calculations.
    Chen SF, Cao Y, Han S, Chen JZ.
    J Mol Graph Model; 2014 Mar; 48():36-46. PubMed ID: 24374242
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  • 8. Autoregulation of kinase dephosphorylation by ATP binding in AGC protein kinases.
    Chan TO, Pascal JM, Armen RS, Rodeck U.
    Cell Cycle; 2012 Feb 01; 11(3):475-8. PubMed ID: 22262182
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  • 9. Resistance of Akt kinases to dephosphorylation through ATP-dependent conformational plasticity.
    Chan TO, Zhang J, Rodeck U, Pascal JM, Armen RS, Spring M, Dumitru CD, Myers V, Li X, Cheung JY, Feldman AM.
    Proc Natl Acad Sci U S A; 2011 Nov 15; 108(46):E1120-7. PubMed ID: 22031698
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  • 11. Novel imidazolopyrimidines as dual PI3-Kinase/mTOR inhibitors.
    Venkatesan AM, Dehnhardt CM, Chen Z, Santos ED, Dos Santos O, Bursavich M, Gilbert AM, Ellingboe JW, Ayral-Kaloustian S, Khafizova G, Brooijmans N, Mallon R, Hollander I, Feldberg L, Lucas J, Yu K, Gibbons J, Abraham R, Mansour TS.
    Bioorg Med Chem Lett; 2010 Jan 15; 20(2):653-6. PubMed ID: 19954970
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  • 12. Theoretical Investigation of the Structural Characteristics in the Active State of Akt1 Kinase.
    Liu L, Fan S, Li W, Tao W, Shi T, Zhao YL.
    J Chem Inf Model; 2019 Jan 28; 59(1):316-325. PubMed ID: 30571108
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  • 16. Crystal structure of human AKT1 with an allosteric inhibitor reveals a new mode of kinase inhibition.
    Wu WI, Voegtli WC, Sturgis HL, Dizon FP, Vigers GP, Brandhuber BJ.
    PLoS One; 2010 Sep 23; 5(9):e12913. PubMed ID: 20886116
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  • 18. The PI3K/Akt pathway: recent progress in the development of ATP-competitive and allosteric Akt kinase inhibitors.
    Lindsley CW, Barnett SF, Layton ME, Bilodeau MT.
    Curr Cancer Drug Targets; 2008 Feb 23; 8(1):7-18. PubMed ID: 18288939
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  • 19. Productive induced metastability in allosteric modulation of kinase function.
    Montes de Oca J, Rodriguez Fris A, Appignanesi G, Fernández A.
    FEBS J; 2014 Jul 23; 281(13):3079-91. PubMed ID: 24823615
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  • 20. Bitopic Inhibition of ATP and Substrate Binding in Ser/Thr Kinases through a Conserved Allosteric Mechanism.
    Ma N, Lippert LG, Devamani T, Levy B, Lee S, Sandhu M, Vaidehi N, Sivaramakrishnan S.
    Biochemistry; 2018 Nov 13; 57(45):6387-6390. PubMed ID: 30339352
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