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PUBMED FOR HANDHELDS

Journal Abstract Search


189 related items for PubMed ID: 27806648

  • 21. Interactions of N-{[2-(4-phenyl-piperazin-1-yl)-ethyl]-phenyl}-2-aryl-2-yl-acetamides and 1-{[2-(4-phenyl-piperazin-1-yl)-ethyl]-phenyl}-3-aryl-2-yl-ureas with dopamine D2 and 5-hydroxytryptamine 5HT(1A) receptors.
    Sukalovic V, Ignjatovic D, Tovilovic G, Andric D, Shakib K, Kostic-Rajacic S, Soskic V.
    Bioorg Med Chem Lett; 2012 Jun 15; 22(12):3967-72. PubMed ID: 22607670
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  • 23. Structure-Based Design and Optimization of FPPQ, a Dual-Acting 5-HT3 and 5-HT6 Receptor Antagonist with Antipsychotic and Procognitive Properties.
    Zajdel P, Grychowska K, Mogilski S, Kurczab R, Satała G, Bugno R, Kos T, Gołębiowska J, Malikowska-Racia N, Nikiforuk A, Chaumont-Dubel S, Bantreil X, Pawłowski M, Martinez J, Subra G, Lamaty F, Marin P, Bojarski AJ, Popik P.
    J Med Chem; 2021 Sep 23; 64(18):13279-13298. PubMed ID: 34467765
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  • 26. Design, synthesis and pharmacological evaluation of conformationally restricted N-arylsulfonyl-3-aminoalkoxy indoles as a potential 5-HT6 receptor ligands.
    Nirogia RV, Kambhampati R, Daulatabad AV, Gudla P, Shaikh M, Achanta PK, Shinde AK, Dubey PK.
    J Enzyme Inhib Med Chem; 2011 Jun 23; 26(3):341-9. PubMed ID: 21524149
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  • 28. AVN-322 is a Safe Orally Bio-Available Potent and Highly Selective Antagonist of 5-HT6R with Demonstrated Ability to Improve Impaired Memory in Animal Models.
    Ivachtchenko AV, Ivanenkov YA, Veselov MS, Okun IM.
    Curr Alzheimer Res; 2017 Jun 23; 14(3):268-294. PubMed ID: 27829340
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  • 29. Fluorination of 3-(3-(piperidin-1-yl)propyl)indoles and 3-(3-(piperazin-1-yl)propyl)indoles gives selective human 5-HT1D receptor ligands with improved pharmacokinetic profiles.
    van Niel MB, Collins I, Beer MS, Broughton HB, Cheng SK, Goodacre SC, Heald A, Locker KL, MacLeod AM, Morrison D, Moyes CR, O'Connor D, Pike A, Rowley M, Russell MG, Sohal B, Stanton JA, Thomas S, Verrier H, Watt AP, Castro JL.
    J Med Chem; 1999 Jun 17; 42(12):2087-104. PubMed ID: 10377215
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  • 34. Design and synthesis of novel N-sulfonyl-2-indoles that behave as 5-HT6 receptor ligands with significant selectivity for D3 over D2 receptors.
    Saavedra OM, Karila D, Brossard D, Rojas A, Dupuis D, Gohier A, Mannoury la Cour C, Millan MJ, Ortuno JC, Hanessian S.
    Bioorg Med Chem; 2017 Jan 01; 25(1):38-52. PubMed ID: 28029458
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  • 37. Lu AE58054, a 5-HT6 antagonist, reverses cognitive impairment induced by subchronic phencyclidine in a novel object recognition test in rats.
    Arnt J, Bang-Andersen B, Grayson B, Bymaster FP, Cohen MP, DeLapp NW, Giethlen B, Kreilgaard M, McKinzie DL, Neill JC, Nelson DL, Nielsen SM, Poulsen MN, Schaus JM, Witten LM.
    Int J Neuropsychopharmacol; 2010 Sep 01; 13(8):1021-33. PubMed ID: 20569520
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  • 40. Synthesis and computer-aided SAR studies for derivatives of phenoxyalkyl-1,3,5-triazine as the new potent ligands for serotonin receptors 5-HT6.
    Ali W, Więcek M, Łażewska D, Kurczab R, Jastrzębska-Więsek M, Satała G, Kucwaj-Brysz K, Lubelska A, Głuch-Lutwin M, Mordyl B, Siwek A, Nasim MJ, Partyka A, Sudoł S, Latacz G, Wesołowska A, Kieć-Kononowicz K, Handzlik J.
    Eur J Med Chem; 2019 Sep 15; 178():740-751. PubMed ID: 31229876
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