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Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

95 related items for PubMed ID: 27807842

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  • 2. Structural and Functional Analysis of the Allosteric Inhibition of IRE1α with ATP-Competitive Ligands.
    Feldman HC, Tong M, Wang L, Meza-Acevedo R, Gobillot TA, Lebedev I, Gliedt MJ, Hari SB, Mitra AK, Backes BJ, Papa FR, Seeliger MA, Maly DJ.
    ACS Chem Biol; 2016 Aug 19; 11(8):2195-205. PubMed ID: 27227314
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  • 5. Allosteric inhibition of the IRE1α RNase preserves cell viability and function during endoplasmic reticulum stress.
    Ghosh R, Wang L, Wang ES, Perera BG, Igbaria A, Morita S, Prado K, Thamsen M, Caswell D, Macias H, Weiberth KF, Gliedt MJ, Alavi MV, Hari SB, Mitra AK, Bhhatarai B, Schürer SC, Snapp EL, Gould DB, German MS, Backes BJ, Maly DJ, Oakes SA, Papa FR.
    Cell; 2014 Jul 31; 158(3):534-48. PubMed ID: 25018104
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  • 6. Binding to an Unusual Inactive Kinase Conformation by Highly Selective Inhibitors of Inositol-Requiring Enzyme 1α Kinase-Endoribonuclease.
    Colombano G, Caldwell JJ, Matthews TP, Bhatia C, Joshi A, McHardy T, Mok NY, Newbatt Y, Pickard L, Strover J, Hedayat S, Walton MI, Myers SM, Jones AM, Saville H, McAndrew C, Burke R, Eccles SA, Davies FE, Bayliss R, Collins I.
    J Med Chem; 2019 Mar 14; 62(5):2447-2465. PubMed ID: 30779566
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  • 7. Pharmacological Targeting of IRE1 in Cancer.
    Raymundo DP, Doultsinos D, Guillory X, Carlesso A, Eriksson LA, Chevet E.
    Trends Cancer; 2020 Dec 14; 6(12):1018-1030. PubMed ID: 32861679
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  • 12. Identification of autophosphorylation inhibitors of the inositol-requiring enzyme 1 alpha (IRE1α) by high-throughput screening using a DELFIA assay.
    Newbatt Y, Hardcastle A, McAndrew PC, Strover JA, Mirza A, Morgan GJ, Burke R, Davies FE, Collins I, van Montfort RL.
    J Biomol Screen; 2013 Mar 14; 18(3):298-308. PubMed ID: 23139381
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  • 13. Allosteric Modulation of Src Family Kinases with ATP-Competitive Inhibitors.
    Register AC, Chakraborty S, Maly DJ.
    Methods Mol Biol; 2017 Mar 14; 1636():79-89. PubMed ID: 28730474
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  • 14. Clustering of IRE1α depends on sensing ER stress but not on its RNase activity.
    Ricci D, Marrocco I, Blumenthal D, Dibos M, Eletto D, Vargas J, Boyle S, Iwamoto Y, Chomistek S, Paton JC, Paton AW, Argon Y.
    FASEB J; 2019 Sep 14; 33(9):9811-9827. PubMed ID: 31199681
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  • 15. A kinase inhibitor activates the IRE1alpha RNase to confer cytoprotection against ER stress.
    Han D, Upton JP, Hagen A, Callahan J, Oakes SA, Papa FR.
    Biochem Biophys Res Commun; 2008 Jan 25; 365(4):777-83. PubMed ID: 18035051
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  • 16. Disruption of IRE1α through its kinase domain attenuates multiple myeloma.
    Harnoss JM, Le Thomas A, Shemorry A, Marsters SA, Lawrence DA, Lu M, Chen YA, Qing J, Totpal K, Kan D, Segal E, Merchant M, Reichelt M, Ackerly Wallweber H, Wang W, Clark K, Kaufman S, Beresini MH, Laing ST, Sandoval W, Lorenzo M, Wu J, Ly J, De Bruyn T, Heidersbach A, Haley B, Gogineni A, Weimer RM, Lee D, Braun MG, Rudolph J, VanWyngarden MJ, Sherbenou DW, Gomez-Bougie P, Amiot M, Acosta-Alvear D, Walter P, Ashkenazi A.
    Proc Natl Acad Sci U S A; 2019 Aug 13; 116(33):16420-16429. PubMed ID: 31371506
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  • 17. Peptides derived from the bifunctional kinase/RNase enzyme IRE1α modulate IRE1α activity and protect cells from endoplasmic reticulum stress.
    Bouchecareilh M, Higa A, Fribourg S, Moenner M, Chevet E.
    FASEB J; 2011 Sep 13; 25(9):3115-29. PubMed ID: 21680894
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  • 18. Regulation of chondrocyte differentiation by IRE1α depends on its enzymatic activity.
    Guo FJ, Jiang R, Li X, Zhang P, Han X, Liu C.
    Cell Signal; 2014 Sep 13; 26(9):1998-2007. PubMed ID: 24863879
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  • 19. Opposite Roles of RNase and Kinase Activities of Inositol-Requiring Enzyme 1 (IRE1) on HSV-1 Replication.
    Su A, Wang H, Li Y, Wang X, Chen D, Wu Z.
    Viruses; 2017 Aug 23; 9(9):. PubMed ID: 28832521
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  • 20. Glioblastoma invasion and cooption depend on IRE1α endoribonuclease activity.
    Jabouille A, Delugin M, Pineau R, Dubrac A, Soulet F, Lhomond S, Pallares-Lupon N, Prats H, Bikfalvi A, Chevet E, Touriol C, Moenner M.
    Oncotarget; 2015 Sep 22; 6(28):24922-34. PubMed ID: 26325176
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