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Journal Abstract Search

95 related items for PubMed ID: 27807842

  • 21. The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis.
    Zhang K, Wong HN, Song B, Miller CN, Scheuner D, Kaufman RJ.
    J Clin Invest; 2005 Feb; 115(2):268-81. PubMed ID: 15690081
    [Abstract] [Full Text] [Related]

  • 22. Inhibition of IRE1α-driven pro-survival pathways is a promising therapeutic application in acute myeloid leukemia.
    Sun H, Lin DC, Guo X, Kharabi Masouleh B, Gery S, Cao Q, Alkan S, Ikezoe T, Akiba C, Paquette R, Chien W, Müller-Tidow C, Jing Y, Agelopoulos K, Müschen M, Koeffler HP.
    Oncotarget; 2016 Apr 05; 7(14):18736-49. PubMed ID: 26934650
    [Abstract] [Full Text] [Related]

  • 23. Kinase Photoaffinity Labeling Reveals Low Selectivity Profile of the IRE1 Targeting Imidazopyrazine-Based KIRA6 Inhibitor.
    Korovesis D, Rufo N, Derua R, Agostinis P, Verhelst SHL.
    ACS Chem Biol; 2020 Dec 18; 15(12):3106-3111. PubMed ID: 33290055
    [Abstract] [Full Text] [Related]

  • 24. Bidirectional Allosteric Communication between the ATP-Binding Site and the Regulatory PIF Pocket in PDK1 Protein Kinase.
    Schulze JO, Saladino G, Busschots K, Neimanis S, Süß E, Odadzic D, Zeuzem S, Hindie V, Herbrand AK, Lisa MN, Alzari PM, Gervasio FL, Biondi RM.
    Cell Chem Biol; 2016 Oct 20; 23(10):1193-1205. PubMed ID: 27693059
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  • 28. A Covalent Cysteine-Targeting Kinase Inhibitor of Ire1 Permits Allosteric Control of Endoribonuclease Activity.
    Waller DD, Jansen G, Golizeh M, Martel-Lorion C, Dejgaard K, Shiao TC, Mancuso J, Tsantrizos YS, Roy R, Sebag M, Sleno L, Thomas DY.
    Chembiochem; 2016 May 03; 17(9):843-51. PubMed ID: 26792008
    [Abstract] [Full Text] [Related]

  • 29. Molecular mechanisms of human IRE1 activation through dimerization and ligand binding.
    Joshi A, Newbatt Y, McAndrew PC, Stubbs M, Burke R, Richards MW, Bhatia C, Caldwell JJ, McHardy T, Collins I, Bayliss R.
    Oncotarget; 2015 May 30; 6(15):13019-35. PubMed ID: 25968568
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  • 30. Effect of Kinase Inhibiting RNase Attenuator (KIRA) Compounds on the Formation of Face-to-Face Dimers of Inositol-Requiring Enzyme 1: Insights from Computational Modeling.
    Carlesso A, Chintha C, Gorman AM, Samali A, Eriksson LA.
    Int J Mol Sci; 2019 Nov 06; 20(22):. PubMed ID: 31698846
    [Abstract] [Full Text] [Related]

  • 31. AlphaScreen-based characterization of the bifunctional kinase/RNase IRE1alpha: a novel and atypical drug target.
    Bouchecareilh M, Caruso ME, Roby P, Parent S, Rouleau N, Taouji S, Pluquet O, Bossé R, Moenner M, Chevet E.
    J Biomol Screen; 2010 Apr 06; 15(4):406-17. PubMed ID: 20237204
    [Abstract] [Full Text] [Related]

  • 32. Allosteric Effect of Adenosine Triphosphate on Peptide Recognition by 3'5'-Cyclic Adenosine Monophosphate Dependent Protein Kinase Catalytic Subunits.
    Kivi R, Solovjova K, Haljasorg T, Arukuusk P, Järv J.
    Protein J; 2016 Dec 06; 35(6):459-466. PubMed ID: 27848106
    [Abstract] [Full Text] [Related]

  • 33. Loss of p53 enhances the function of the endoplasmic reticulum through activation of the IRE1α/XBP1 pathway.
    Namba T, Chu K, Kodama R, Byun S, Yoon KW, Hiraki M, Mandinova A, Lee SW.
    Oncotarget; 2015 Aug 21; 6(24):19990-20001. PubMed ID: 26254280
    [Abstract] [Full Text] [Related]

  • 34. Activation of mammalian IRE1alpha upon ER stress depends on dissociation of BiP rather than on direct interaction with unfolded proteins.
    Oikawa D, Kimata Y, Kohno K, Iwawaki T.
    Exp Cell Res; 2009 Sep 10; 315(15):2496-504. PubMed ID: 19538957
    [Abstract] [Full Text] [Related]

  • 35. Detection of allosteric kinase inhibitors by displacement of active site probes.
    Lebakken CS, Reichling LJ, Ellefson JM, Riddle SM.
    J Biomol Screen; 2012 Jul 10; 17(6):813-21. PubMed ID: 22453235
    [Abstract] [Full Text] [Related]

  • 36. IRE1α dissociates with BiP and inhibits ER stress-mediated apoptosis in cartilage development.
    Han X, Zhou J, Zhang P, Song F, Jiang R, Li M, Xia F, Guo FJ.
    Cell Signal; 2013 Nov 10; 25(11):2136-46. PubMed ID: 23816533
    [Abstract] [Full Text] [Related]

  • 37. Functional characterization of peanut serine/threonine/tyrosine protein kinase: molecular docking and inhibition kinetics with tyrosine kinase inhibitors.
    Rudrabhatla P, Rajasekharan R.
    Biochemistry; 2004 Sep 28; 43(38):12123-32. PubMed ID: 15379551
    [Abstract] [Full Text] [Related]

  • 38. Baculovirus-mediated expression, purification, and characterization of a fully activated catalytic kinase domain construct of the 70 kDa 40S ribosomal protein S6 kinase-1 alphaII isoform (S6K1alphaII).
    Keshwani MM, Ross DB, Ragan TJ, Harris TK.
    Protein Expr Purif; 2008 Mar 28; 58(1):32-41. PubMed ID: 18160308
    [Abstract] [Full Text] [Related]

  • 39. An interdomain helix in IRE1α mediates the conformational change required for the sensor's activation.
    Ricci D, Tutton S, Marrocco I, Ying M, Blumenthal D, Eletto D, Vargas J, Boyle S, Fazelinia H, Qian L, Suresh K, Taylor D, Paton JC, Paton AW, Tang CA, Hu CA, Radhakrishnan R, Gidalevitz T, Argon Y.
    J Biol Chem; 2021 Mar 28; 296():100781. PubMed ID: 34000298
    [Abstract] [Full Text] [Related]

  • 40. Design, synthesis, and evaluation of non-ATP-competitive small-molecule Polo-like kinase 1 (Plk1) inhibitors.
    Chen DX, Huang J, Liu M, Xu YG, Jiang C.
    Arch Pharm (Weinheim); 2015 Jan 28; 348(1):2-9. PubMed ID: 25430493
    [Abstract] [Full Text] [Related]

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