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213 related items for PubMed ID: 27809557

  • 1. Comparison of Dapivirine Vaginal Gel and Film Formulation Pharmacokinetics and Pharmacodynamics (FAME 02B).
    Robinson JA, Marzinke MA, Bakshi RP, Fuchs EJ, Radebaugh CL, Aung W, Spiegel HM, Coleman JS, Rohan LC, Hendrix CW.
    AIDS Res Hum Retroviruses; 2017 Apr; 33(4):339-346. PubMed ID: 27809557
    [Abstract] [Full Text] [Related]

  • 2. Comparison of the Pharmacokinetics and Pharmacodynamics of Single-Dose Tenofovir Vaginal Film and Gel Formulation (FAME 05).
    Robinson JA, Marzinke MA, Fuchs EJ, Bakshi RP, Spiegel HML, Coleman JS, Rohan LC, Hendrix CW.
    J Acquir Immune Defic Syndr; 2018 Feb 01; 77(2):175-182. PubMed ID: 29135651
    [Abstract] [Full Text] [Related]

  • 3. A Phase 1 Trial to Assess the Safety, Acceptability, Pharmacokinetics, and Pharmacodynamics of a Novel Dapivirine Vaginal Film.
    Bunge KE, Dezzutti CS, Rohan LC, Hendrix CW, Marzinke MA, Richardson-Harman N, Moncla BJ, Devlin B, Meyn LA, Spiegel HM, Hillier SL.
    J Acquir Immune Defic Syndr; 2016 Apr 15; 71(5):498-505. PubMed ID: 26565716
    [Abstract] [Full Text] [Related]

  • 4. FAME-04: A Phase 1 trial to assess the safety, acceptability, pharmacokinetics and pharmacodynamics of film and gel formulations of tenofovir.
    Bunge KE, Dezzutti CS, Hendrix CW, Marzinke MA, Spiegel HML, Moncla BJ, Schwartz JL, Meyn LA, Richardson-Harman N, Rohan LC, Hillier SL.
    J Int AIDS Soc; 2018 Aug 15; 21(8):e25156. PubMed ID: 30101439
    [Abstract] [Full Text] [Related]

  • 5. Safety, tolerability, and systemic absorption of dapivirine vaginal microbicide gel in healthy, HIV-negative women.
    Nel AM, Coplan P, van de Wijgert JH, Kapiga SH, von Mollendorf C, Geubbels E, Vyankandondera J, Rees HV, Masenga G, Kiwelu I, Moyes J, Smythe SC.
    AIDS; 2009 Jul 31; 23(12):1531-8. PubMed ID: 19550287
    [Abstract] [Full Text] [Related]

  • 6. Pharmacokinetic assessment of dapivirine vaginal microbicide gel in healthy, HIV-negative women.
    Nel AM, Coplan P, Smythe SC, McCord K, Mitchnick M, Kaptur PE, Romano J.
    AIDS Res Hum Retroviruses; 2010 Nov 31; 26(11):1181-90. PubMed ID: 20854207
    [Abstract] [Full Text] [Related]

  • 7. Pharmacokinetics of 2 dapivirine vaginal microbicide gels and their safety vs. Hydroxyethyl cellulose-based universal placebo gel.
    Nel AM, Smythe SC, Habibi S, Kaptur PE, Romano JW.
    J Acquir Immune Defic Syndr; 2010 Oct 31; 55(2):161-9. PubMed ID: 20574411
    [Abstract] [Full Text] [Related]

  • 8. The sheep as a model of preclinical safety and pharmacokinetic evaluations of candidate microbicides.
    Holt JD, Cameron D, Dias N, Holding J, Muntendam A, Oostebring F, Dreier P, Rohan L, Nuttall J.
    Antimicrob Agents Chemother; 2015 Jul 31; 59(7):3761-70. PubMed ID: 25845860
    [Abstract] [Full Text] [Related]

  • 9. Safety and availability of dapivirine (TMC120) delivered from an intravaginal ring.
    Romano J, Variano B, Coplan P, Van Roey J, Douville K, Rosenberg Z, Temmerman M, Verstraelen H, Van Bortel L, Weyers S, Mitchnick M.
    AIDS Res Hum Retroviruses; 2009 May 31; 25(5):483-8. PubMed ID: 19388819
    [Abstract] [Full Text] [Related]

  • 10. Phase 1 Safety, Pharmacokinetics, and Pharmacodynamics of Dapivirine and Maraviroc Vaginal Rings: A Double-Blind Randomized Trial.
    Chen BA, Panther L, Marzinke MA, Hendrix CW, Hoesley CJ, van der Straten A, Husnik MJ, Soto-Torres L, Nel A, Johnson S, Richardson-Harman N, Rabe LK, Dezzutti CS.
    J Acquir Immune Defic Syndr; 2015 Nov 01; 70(3):242-9. PubMed ID: 26034880
    [Abstract] [Full Text] [Related]

  • 11. A safety and pharmacokinetic trial assessing delivery of dapivirine from a vaginal ring in healthy women.
    Nel A, Haazen W, Nuttall J, Romano J, Rosenberg Z, van Niekerk N.
    AIDS; 2014 Jun 19; 28(10):1479-87. PubMed ID: 24901365
    [Abstract] [Full Text] [Related]

  • 12. Phase 2a Safety, Pharmacokinetics, and Acceptability of Dapivirine Vaginal Rings in US Postmenopausal Women.
    Chen BA, Zhang J, Gundacker HM, Hendrix CW, Hoesley CJ, Salata RA, Dezzutti CS, van der Straten A, Hall WB, Jacobson CE, Johnson S, McGowan I, Nel AM, Soto-Torres L, Marzinke MA, MTN-024/IPM 031 Protocol Team for the Microbicide Trials Network.
    Clin Infect Dis; 2019 Mar 19; 68(7):1144-1151. PubMed ID: 30289485
    [Abstract] [Full Text] [Related]

  • 13. Concentrations of dapivirine in the rhesus macaque and rabbit following once daily intravaginal administration of a gel formulation of [14C]dapivirine for 7 days.
    Nuttall JP, Thake DC, Lewis MG, Ferkany JW, Romano JW, Mitchnick MA.
    Antimicrob Agents Chemother; 2008 Mar 19; 52(3):909-14. PubMed ID: 18086845
    [Abstract] [Full Text] [Related]

  • 14. Development and verification of mechanistic vaginal absorption and metabolism model to predict systemic exposure after vaginal ring and gel application.
    Thakur K, Telaprolu KC, Paterson D, Salem F, Arora S, Polak S.
    Br J Clin Pharmacol; 2024 Jun 19; 90(6):1428-1449. PubMed ID: 38450818
    [Abstract] [Full Text] [Related]

  • 15. Pharmacokinetics of Dapivirine Transfer into Blood Plasma, Breast Milk, and Cervicovaginal Fluid of Lactating Women Using the Dapivirine Vaginal Ring.
    Noguchi LM, Hoesley C, Kelly C, Scheckter R, Bunge K, Nel A, Marzinke MA, Hendrix CW, Dezzutti CS, Hillier SL, Bogen DL, Piper JM, Beigi RH.
    Antimicrob Agents Chemother; 2019 Mar 19; 63(3):. PubMed ID: 30602513
    [Abstract] [Full Text] [Related]

  • 16. Pharmacokinetic modeling of a gel-delivered dapivirine microbicide in humans.
    Halwes ME, Steinbach-Rankins JM, Frieboes HB.
    Eur J Pharm Sci; 2016 Oct 10; 93():410-8. PubMed ID: 27559026
    [Abstract] [Full Text] [Related]

  • 17. A randomized male tolerance study of dapivirine gel following multiple topical penile exposures (MTN 012/IPM 010).
    Cranston RD, Hoesley C, Carballo-Diéguez A, Hendrix CW, Husnik M, Levy L, Hall W, Soto-Torres L, Nel AM.
    AIDS Res Hum Retroviruses; 2014 Feb 10; 30(2):184-9. PubMed ID: 24070431
    [Abstract] [Full Text] [Related]

  • 18. Pharmacokinetics and Pharmacodynamics of Tenofovir Reduced-Glycerin 1% Gel in the Rectal and Vaginal Compartments in Women: A Cross-Compartmental Study With Directly Observed Dosing.
    Justman JE, Nair GL, Hendrix CW, Piper JM, Marzinke MA, Dai JY, Pan Z, Galaska B, Levy L, Schwartz JL, Balar B, Kunjara Na Ayudhya RP, Mushamiri I, McGowan I, Dezzutti CS, MTN-014 Study Team.
    J Acquir Immune Defic Syndr; 2018 Jun 01; 78(2):175-182. PubMed ID: 29767639
    [Abstract] [Full Text] [Related]

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