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Journal Abstract Search

404 related items for PubMed ID: 27824936

  • 1. Differential Effects of apoE4 and Activation of ABCA1 on Brain and Plasma Lipoproteins.
    Boehm-Cagan A, Bar R, Harats D, Shaish A, Levkovitz H, Bielicki JK, Johansson JO, Michaelson DM.
    PLoS One; 2016; 11(11):e0166195. PubMed ID: 27824936
    [Abstract] [Full Text] [Related]

  • 2. Abca1 deficiency affects Alzheimer's disease-like phenotype in human ApoE4 but not in ApoE3-targeted replacement mice.
    Fitz NF, Cronican AA, Saleem M, Fauq AH, Chapman R, Lefterov I, Koldamova R.
    J Neurosci; 2012 Sep 19; 32(38):13125-36. PubMed ID: 22993429
    [Abstract] [Full Text] [Related]

  • 3. Reversal of apoE4-driven brain pathology and behavioral deficits by bexarotene.
    Boehm-Cagan A, Michaelson DM.
    J Neurosci; 2014 May 21; 34(21):7293-301. PubMed ID: 24849361
    [Abstract] [Full Text] [Related]

  • 4. A novel apoE-mimetic increases brain apoE levels, reduces Aβ pathology and improves memory when treated before onset of pathology in male mice that express APOE3.
    Valencia-Olvera AC, Balu D, Bellur S, McNally T, Saleh Y, Pham D, Ghura S, York J, Johansson JO, LaDu MJ, Tai L.
    Alzheimers Res Ther; 2023 Dec 15; 15(1):216. PubMed ID: 38102668
    [Abstract] [Full Text] [Related]

  • 5. ABCA1 Agonist Reverses the ApoE4-Driven Cognitive and Brain Pathologies.
    Boehm-Cagan A, Bar R, Liraz O, Bielicki JK, Johansson JO, Michaelson DM.
    J Alzheimers Dis; 2016 Oct 04; 54(3):1219-1233. PubMed ID: 27567858
    [Abstract] [Full Text] [Related]

  • 6. Absence of ApoE upregulates murine brain ApoD and ABCA1 levels, but does not affect brain sterol levels, while human ApoE3 and human ApoE4 upregulate brain cholesterol precursor levels.
    Jansen PJ, Lütjohann D, Thelen KM, von Bergmann K, van Leuven F, Ramaekers FC, Monique M.
    J Alzheimers Dis; 2009 Oct 04; 18(2):319-29. PubMed ID: 19584433
    [Abstract] [Full Text] [Related]

  • 7. Liver X receptor agonist treatment significantly affects phenotype and transcriptome of APOE3 and APOE4 Abca1 haplo-deficient mice.
    Carter AY, Letronne F, Fitz NF, Mounier A, Wolfe CM, Nam KN, Reeves VL, Kamboh H, Lefterov I, Koldamova R.
    PLoS One; 2017 Oct 04; 12(2):e0172161. PubMed ID: 28241068
    [Abstract] [Full Text] [Related]

  • 8. ApoE4 Alters ABCA1 Membrane Trafficking in Astrocytes.
    Rawat V, Wang S, Sima J, Bar R, Liraz O, Gundimeda U, Parekh T, Chan J, Johansson JO, Tang C, Chui HC, Harrington MG, Michaelson DM, Yassine HN.
    J Neurosci; 2019 Nov 27; 39(48):9611-9622. PubMed ID: 31641056
    [Abstract] [Full Text] [Related]

  • 9. Opposing effects of Apoe/Apoa1 double deletion on amyloid-β pathology and cognitive performance in APP mice.
    Fitz NF, Tapias V, Cronican AA, Castranio EL, Saleem M, Carter AY, Lefterova M, Lefterov I, Koldamova R.
    Brain; 2015 Dec 27; 138(Pt 12):3699-715. PubMed ID: 26510953
    [Abstract] [Full Text] [Related]

  • 10. Amyloid-β pathology and APOE genotype modulate retinoid X receptor agonist activity in vivo.
    Tai LM, Koster KP, Luo J, Lee SH, Wang YT, Collins NC, Ben Aissa M, Thatcher GRJ, LaDu MJ.
    J Biol Chem; 2014 Oct 31; 289(44):30538-30555. PubMed ID: 25217640
    [Abstract] [Full Text] [Related]

  • 11. Modulation of Alzheimer-like synaptic and cholinergic deficits in transgenic mice by human apolipoprotein E depends on isoform, aging, and overexpression of amyloid beta peptides but not on plaque formation.
    Buttini M, Yu GQ, Shockley K, Huang Y, Jones B, Masliah E, Mallory M, Yeo T, Longo FM, Mucke L.
    J Neurosci; 2002 Dec 15; 22(24):10539-48. PubMed ID: 12486146
    [Abstract] [Full Text] [Related]

  • 12. Reversal of ApoE4-Driven Brain Pathology by Vascular Endothelial Growth Factor Treatment.
    Salomon-Zimri S, Glat MJ, Barhum Y, Luz I, Boehm-Cagan A, Liraz O, Ben-Zur T, Offen D, Michaelson DM.
    J Alzheimers Dis; 2016 Jun 30; 53(4):1443-58. PubMed ID: 27372644
    [Abstract] [Full Text] [Related]

  • 13. Central and Peripheral Mechanisms in ApoE4-Driven Diabetic Pathology.
    Koren-Iton A, Salomon-Zimri S, Smolar A, Shavit-Stein E, Dori A, Chapman J, Michaelson DM.
    Int J Mol Sci; 2020 Feb 14; 21(4):. PubMed ID: 32075060
    [Abstract] [Full Text] [Related]

  • 14. Opposing effects of viral mediated brain expression of apolipoprotein E2 (apoE2) and apoE4 on apoE lipidation and Aβ metabolism in apoE4-targeted replacement mice.
    Hu J, Liu CC, Chen XF, Zhang YW, Xu H, Bu G.
    Mol Neurodegener; 2015 Mar 05; 10():6. PubMed ID: 25871773
    [Abstract] [Full Text] [Related]

  • 15. Accumulation of amyloid-β in the brain of mouse models of Alzheimer's disease is modified by altered gene expression in the presence of human apoE isoforms during aging.
    Honda K, Saito Y, Saito H, Toyoda M, Abe R, Saito T, Saido TC, Michikawa M, Taru H, Sobu Y, Hata S, Nakaya T, Suzuki T.
    Neurobiol Aging; 2023 Mar 05; 123():63-74. PubMed ID: 36638682
    [Abstract] [Full Text] [Related]

  • 16. Intraneuronal amyloid-beta plays a role in mediating the synergistic pathological effects of apoE4 and environmental stimulation.
    Levi O, Dolev I, Belinson H, Michaelson DM.
    J Neurochem; 2007 Nov 05; 103(3):1031-40. PubMed ID: 17666042
    [Abstract] [Full Text] [Related]

  • 17. Apolipoprotein E and oxidative stress in brain with relevance to Alzheimer's disease.
    Butterfield DA, Mattson MP.
    Neurobiol Dis; 2020 May 05; 138():104795. PubMed ID: 32036033
    [Abstract] [Full Text] [Related]

  • 18. Neuron-specific apolipoprotein e4 proteolysis is associated with increased tau phosphorylation in brains of transgenic mice.
    Brecht WJ, Harris FM, Chang S, Tesseur I, Yu GQ, Xu Q, Dee Fish J, Wyss-Coray T, Buttini M, Mucke L, Mahley RW, Huang Y.
    J Neurosci; 2004 Mar 10; 24(10):2527-34. PubMed ID: 15014128
    [Abstract] [Full Text] [Related]

  • 19. Interaction of nascent ApoE2, ApoE3, and ApoE4 isoforms expressed in mammalian cells with amyloid peptide beta (1-40). Relevance to Alzheimer's disease.
    Aleshkov S, Abraham CR, Zannis VI.
    Biochemistry; 1997 Aug 26; 36(34):10571-80. PubMed ID: 9265639
    [Abstract] [Full Text] [Related]

  • 20. APOE4-mediated amyloid-β pathology depends on its neuronal receptor LRP1.
    Tachibana M, Holm ML, Liu CC, Shinohara M, Aikawa T, Oue H, Yamazaki Y, Martens YA, Murray ME, Sullivan PM, Weyer K, Glerup S, Dickson DW, Bu G, Kanekiyo T.
    J Clin Invest; 2019 Mar 01; 129(3):1272-1277. PubMed ID: 30741718
    [Abstract] [Full Text] [Related]

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