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Journal Abstract Search

188 related items for PubMed ID: 27835059

  • 1. Epalrestat, an Aldose Reductase Inhibitor Prevents Glucose-Induced Toxicity in Human Retinal Pigment Epithelial Cells In Vitro.
    Senthilkumari S, Sharmila R, Chidambaranathan G, Vanniarajan A.
    J Ocul Pharmacol Ther; 2017; 33(1):34-41. PubMed ID: 27835059
    [Abstract] [Full Text] [Related]

  • 2. Ranirestat has a stronger inhibitory activity on aldose reductase and suppresses inflammatory reactions in high glucose-exposed endothelial cells.
    Ishibashi Y, Matsui T, Matsumoto T, Kato H, Yamagishi S.
    Diab Vasc Dis Res; 2016 Jul; 13(4):312-5. PubMed ID: 27190083
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and biological evaluation of new epalrestat analogues as aldose reductase inhibitors (ARIs).
    Reddy TN, Ravinder M, Bagul P, Ravikanti K, Bagul C, Nanubolu JB, Srinivas K, Banerjee SK, Rao VJ.
    Eur J Med Chem; 2014 Jan; 71():53-66. PubMed ID: 24275248
    [Abstract] [Full Text] [Related]

  • 4. Gedunin, A Neem Limonoid in Combination with Epalrestat Inhibits Cancer Hallmarks by Attenuating Aldose Reductase-Driven Oncogenic Signaling in SCC131 Oral Cancer Cells.
    Tanagala KKK, Baba AB, Kowshik J, Reddy GB, Nagini S.
    Anticancer Agents Med Chem; 2018 Jan; 18(14):2042-2052. PubMed ID: 30062975
    [Abstract] [Full Text] [Related]

  • 5. Polyol pathway and protein kinase C activity of rat Schwannoma cells.
    Kamiya H, Nakamura J, Hamada Y, Nakashima E, Naruse K, Kato K, Yasuda Y, Hotta N.
    Diabetes Metab Res Rev; 2003 Jan; 19(2):131-9. PubMed ID: 12673781
    [Abstract] [Full Text] [Related]

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  • 7. The aldose reductase inhibitor epalrestat exerts nephritic protection on diabetic nephropathy in db/db mice through metabolic modulation.
    He J, Gao HX, Yang N, Zhu XD, Sun RB, Xie Y, Zeng CH, Zhang JW, Wang JK, Ding F, Aa JY, Wang GJ.
    Acta Pharmacol Sin; 2019 Jan; 40(1):86-97. PubMed ID: 29930278
    [Abstract] [Full Text] [Related]

  • 8. Renoprotective Effects of Aldose Reductase Inhibitor Epalrestat against High Glucose-Induced Cellular Injury.
    El Gamal H, Eid AH, Munusamy S.
    Biomed Res Int; 2017 Jan; 2017():5903105. PubMed ID: 28386557
    [Abstract] [Full Text] [Related]

  • 9. An aldose reductase inhibitor prevents glucose-induced increase in transforming growth factor-beta and protein kinase C activity in cultured mesangial cells.
    Ishii H, Tada H, Isogai S.
    Diabetologia; 1998 Mar; 41(3):362-4. PubMed ID: 9541179
    [Abstract] [Full Text] [Related]

  • 10. Mechanisms of inhibitory activity of the aldose reductase inhibitor, epalrestat, on high glucose-mediated endothelial injury: neutrophil-endothelial cell adhesion and surface expression of endothelial adhesion molecules.
    Okayama N, Omi H, Okouchi M, Imaeda K, Kato T, Akao M, Imai S, Shimizu M, Fukutomi T, Itoh M.
    J Diabetes Complications; 2002 Mar; 16(5):321-6. PubMed ID: 12200074
    [Abstract] [Full Text] [Related]

  • 11. Aldose reductase inhibitor improves insulin-mediated glucose uptake and prevents migration of human coronary artery smooth muscle cells induced by high glucose.
    Yasunari K, Kohno M, Kano H, Minami M, Yoshikawa J.
    Hypertension; 2000 May; 35(5):1092-8. PubMed ID: 10818070
    [Abstract] [Full Text] [Related]

  • 12. Long-term clinical effects of epalrestat, an aldose reductase inhibitor, on progression of diabetic neuropathy and other microvascular complications: multivariate epidemiological analysis based on patient background factors and severity of diabetic neuropathy.
    Hotta N, Kawamori R, Fukuda M, Shigeta Y, Aldose Reductase Inhibitor-Diabetes Complications Trial Study Group.
    Diabet Med; 2012 Dec; 29(12):1529-33. PubMed ID: 22507139
    [Abstract] [Full Text] [Related]

  • 13. An aldose reductase inhibitor prevents the glucose-induced increase in PDGF-beta receptor in cultured rat aortic smooth muscle cells.
    Kasuya Y, Nakamura J, Hamada Y, Nakayama M, Sasaki H, Komori T, Chaya S, Watanabe G, Naruse K, Nakashima E, Kato K, Hotta N.
    Biochem Biophys Res Commun; 1999 Aug 11; 261(3):853-8. PubMed ID: 10441515
    [Abstract] [Full Text] [Related]

  • 14. Aldose reductase inhibition alleviates hyperglycemic effects on human retinal pigment epithelial cells.
    Chang KC, Snow A, LaBarbera DV, Petrash JM.
    Chem Biol Interact; 2015 Jun 05; 234():254-60. PubMed ID: 25451566
    [Abstract] [Full Text] [Related]

  • 15. Pharmacological properties of fidarestat, a potent aldose reductase inhibitor, clarified by using sorbitol in human and rat erythrocytes.
    Sobajima H, Aoki T, Sassa H, Suzuki T, Taniko K, Makino M, Mizuno K, Suzuki T.
    Pharmacology; 2001 May 05; 62(4):193-9. PubMed ID: 11359994
    [Abstract] [Full Text] [Related]

  • 16. In vitro retinal and erythrocyte polyol pathway regulation by hormones and an aldose reductase inhibitor.
    Hotta N, Kakuta H, Koh N, Fukasawa H, Yasuma T, Awaya S, Sakamoto N.
    Diabetes Res Clin Pract; 1991 Oct 05; 14(1):29-35. PubMed ID: 1748061
    [Abstract] [Full Text] [Related]

  • 17. Restoration of nitric oxide production by aldose reductase inhibitor in human endothelial cells cultured in high-glucose medium.
    Okuda Y, Kawashima K, Suzuki S, Asakura Y, Asano M, Tsurumaru K, Dai H, Tachi Y, Bannai C, Saitoh M, Yamashita K.
    Life Sci; 1997 Oct 05; 60(3):PL53-6. PubMed ID: 9000650
    [Abstract] [Full Text] [Related]

  • 18. Effects of aldose reductase inhibitor on microneurographically assessed peripheral sympathetic nerve activity in rats.
    Sato D, Kusunoki M, Shinzawa G, Feng Z, Nishina A, Nakamura T.
    Auton Neurosci; 2015 Dec 05; 193():69-73. PubMed ID: 26272532
    [Abstract] [Full Text] [Related]

  • 19. In vitro and in vivo inhibition of aldose reductase and advanced glycation end products by phloretin, epigallocatechin 3-gallate and [6]-gingerol.
    Sampath C, Sang S, Ahmedna M.
    Biomed Pharmacother; 2016 Dec 05; 84():502-513. PubMed ID: 27685794
    [Abstract] [Full Text] [Related]

  • 20. [Inhibition effect of epalrestat on rat lens osmotic expansion].
    Ji LX, Shen N, Li CN, Liu Q, Huan Y, Shen ZF.
    Yao Xue Xue Bao; 2009 Oct 05; 44(10):1107-11. PubMed ID: 20055132
    [Abstract] [Full Text] [Related]

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