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Journal Abstract Search

630 related items for PubMed ID: 27875302

  • 1. Proteasomal Degradation of the EWS-FLI1 Fusion Protein Is Regulated by a Single Lysine Residue.
    Gierisch ME, Pfistner F, Lopez-Garcia LA, Harder L, Schäfer BW, Niggli FK.
    J Biol Chem; 2016 Dec 23; 291(52):26922-26933. PubMed ID: 27875302
    [Abstract] [Full Text] [Related]

  • 2. High-throughput RNAi screen in Ewing sarcoma cells identifies leucine rich repeats and WD repeat domain containing 1 (LRWD1) as a regulator of EWS-FLI1 driven cell viability.
    He T, Surdez D, Rantala JK, Haapa-Paananen S, Ban J, Kauer M, Tomazou E, Fey V, Alonso J, Kovar H, Delattre O, Iljin K.
    Gene; 2017 Jan 05; 596():137-146. PubMed ID: 27760381
    [Abstract] [Full Text] [Related]

  • 3. USP19 deubiquitinates EWS-FLI1 to regulate Ewing sarcoma growth.
    Gierisch ME, Pedot G, Walser F, Lopez-Garcia LA, Jaaks P, Niggli FK, Schäfer BW.
    Sci Rep; 2019 Jan 30; 9(1):951. PubMed ID: 30700749
    [Abstract] [Full Text] [Related]

  • 4. EWS-FLI1 and Menin Converge to Regulate ATF4 Activity in Ewing Sarcoma.
    Jiménez JA, Apfelbaum AA, Hawkins AG, Svoboda LK, Kumar A, Ruiz RO, Garcia AX, Haarer E, Nwosu ZC, Bradin J, Purohit T, Chen D, Cierpicki T, Grembecka J, Lyssiotis CA, Lawlor ER.
    Mol Cancer Res; 2021 Jul 30; 19(7):1182-1195. PubMed ID: 33741715
    [Abstract] [Full Text] [Related]

  • 5. Impairment of p53 acetylation by EWS-Fli1 chimeric protein in Ewing family tumors.
    Li Y, Li X, Fan G, Fukushi J, Matsumoto Y, Iwamoto Y, Zhu Y.
    Cancer Lett; 2012 Jul 01; 320(1):14-22. PubMed ID: 22266186
    [Abstract] [Full Text] [Related]

  • 6. Suppression of FOXO1 is responsible for a growth regulatory repressive transcriptional sub-signature of EWS-FLI1 in Ewing sarcoma.
    Niedan S, Kauer M, Aryee DN, Kofler R, Schwentner R, Meier A, Pötschger U, Kontny U, Kovar H.
    Oncogene; 2014 Jul 24; 33(30):3927-38. PubMed ID: 23995784
    [Abstract] [Full Text] [Related]

  • 7. PI3K/AKT signaling modulates transcriptional expression of EWS/FLI1 through specificity protein 1.
    Giorgi C, Boro A, Rechfeld F, Lopez-Garcia LA, Gierisch ME, Schäfer BW, Niggli FK.
    Oncotarget; 2015 Oct 06; 6(30):28895-910. PubMed ID: 26336820
    [Abstract] [Full Text] [Related]

  • 8. SLFN11 Is a Transcriptional Target of EWS-FLI1 and a Determinant of Drug Response in Ewing Sarcoma.
    Tang SW, Bilke S, Cao L, Murai J, Sousa FG, Yamade M, Rajapakse V, Varma S, Helman LJ, Khan J, Meltzer PS, Pommier Y.
    Clin Cancer Res; 2015 Sep 15; 21(18):4184-93. PubMed ID: 25779942
    [Abstract] [Full Text] [Related]

  • 9. Ablation of EWS-FLI1 by USP9X inhibition suppresses cancer cell growth in Ewing sarcoma.
    Wang S, Huo X, Yang Y, Mo Y, Kollipara RK, Kittler R.
    Cancer Lett; 2023 Jan 01; 552():215984. PubMed ID: 36330954
    [Abstract] [Full Text] [Related]

  • 10. EWS-FLI1 reprograms the metabolism of Ewing sarcoma cells via positive regulation of glutamine import and serine-glycine biosynthesis.
    Sen N, Cross AM, Lorenzi PL, Khan J, Gryder BE, Kim S, Caplen NJ.
    Mol Carcinog; 2018 Oct 01; 57(10):1342-1357. PubMed ID: 29873416
    [Abstract] [Full Text] [Related]

  • 11. MiR-30a-5p connects EWS-FLI1 and CD99, two major therapeutic targets in Ewing tumor.
    Franzetti GA, Laud-Duval K, Bellanger D, Stern MH, Sastre-Garau X, Delattre O.
    Oncogene; 2013 Aug 15; 32(33):3915-21. PubMed ID: 22986530
    [Abstract] [Full Text] [Related]

  • 12. Targeting the EWS-ETS transcriptional program by BET bromodomain inhibition in Ewing sarcoma.
    Hensel T, Giorgi C, Schmidt O, Calzada-Wack J, Neff F, Buch T, Niggli FK, Schäfer BW, Burdach S, Richter GH.
    Oncotarget; 2016 Jan 12; 7(2):1451-63. PubMed ID: 26623725
    [Abstract] [Full Text] [Related]

  • 13. Systems biology of Ewing sarcoma: a network model of EWS-FLI1 effect on proliferation and apoptosis.
    Stoll G, Surdez D, Tirode F, Laud K, Barillot E, Zinovyev A, Delattre O.
    Nucleic Acids Res; 2013 Oct 12; 41(19):8853-71. PubMed ID: 23935076
    [Abstract] [Full Text] [Related]

  • 14. Selective inhibition of HDAC6 regulates expression of the oncogenic driver EWSR1-FLI1 through the EWSR1 promoter in Ewing sarcoma.
    García-Domínguez DJ, Hajji N, Sánchez-Molina S, Figuerola-Bou E, de Pablos RM, Espinosa-Oliva AM, Andrés-León E, Terrón-Camero LC, Flores-Campos R, Pascual-Pasto G, Robles MJ, Machado I, Llombart-Bosch A, Magagnoli G, Scotlandi K, Carcaboso ÁM, Mora J, de Álava E, Hontecillas-Prieto L.
    Oncogene; 2021 Sep 12; 40(39):5843-5853. PubMed ID: 34345016
    [Abstract] [Full Text] [Related]

  • 15. FOXM1 is an oncogenic mediator in Ewing Sarcoma.
    Christensen L, Joo J, Lee S, Wai D, Triche TJ, May WA.
    PLoS One; 2013 Sep 12; 8(1):e54556. PubMed ID: 23365673
    [Abstract] [Full Text] [Related]

  • 16. EWS-FLI1 regulates a transcriptional program in cooperation with Foxq1 in mouse Ewing sarcoma.
    Shimizu R, Tanaka M, Tsutsumi S, Aburatani H, Yamazaki Y, Homme M, Kitagawa Y, Nakamura T.
    Cancer Sci; 2018 Sep 12; 109(9):2907-2918. PubMed ID: 29945296
    [Abstract] [Full Text] [Related]

  • 17. A zebrafish transgenic model of Ewing's sarcoma reveals conserved mediators of EWS-FLI1 tumorigenesis.
    Leacock SW, Basse AN, Chandler GL, Kirk AM, Rakheja D, Amatruda JF.
    Dis Model Mech; 2012 Jan 12; 5(1):95-106. PubMed ID: 21979944
    [Abstract] [Full Text] [Related]

  • 18. The FLI portion of EWS/FLI contributes a transcriptional regulatory function that is distinct and separable from its DNA-binding function in Ewing sarcoma.
    Boone MA, Taslim C, Crow JC, Selich-Anderson J, Byrum AK, Showpnil IA, Sunkel BD, Wang M, Stanton BZ, Theisen ER, Lessnick SL.
    Oncogene; 2021 Jul 12; 40(29):4759-4769. PubMed ID: 34145397
    [Abstract] [Full Text] [Related]

  • 19. The orphan nuclear receptor DAX1 is up-regulated by the EWS/FLI1 oncoprotein and is highly expressed in Ewing tumors.
    Mendiola M, Carrillo J, García E, Lalli E, Hernández T, de Alava E, Tirode F, Delattre O, García-Miguel P, López-Barea F, Pestaña A, Alonso J.
    Int J Cancer; 2006 Mar 15; 118(6):1381-9. PubMed ID: 16206264
    [Abstract] [Full Text] [Related]

  • 20. BET bromodomain inhibitors suppress EWS-FLI1-dependent transcription and the IGF1 autocrine mechanism in Ewing sarcoma.
    Loganathan SN, Tang N, Fleming JT, Ma Y, Guo Y, Borinstein SC, Chiang C, Wang J.
    Oncotarget; 2016 Jul 12; 7(28):43504-43517. PubMed ID: 27259270
    [Abstract] [Full Text] [Related]

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