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196 related items for PubMed ID: 27888145

  • 1. Critical role of hnRNP A1 in activating KRAS transcription in pancreatic cancer cells: A molecular mechanism involving G4 DNA.
    Cogoi S, Rapozzi V, Cauci S, Xodo LE.
    Biochim Biophys Acta Gen Subj; 2017 May; 1861(5 Pt B):1389-1398. PubMed ID: 27888145
    [Abstract] [Full Text] [Related]

  • 2. Protein hnRNP A1 and its derivative Up1 unfold quadruplex DNA in the human KRAS promoter: implications for transcription.
    Paramasivam M, Membrino A, Cogoi S, Fukuda H, Nakagama H, Xodo LE.
    Nucleic Acids Res; 2009 May; 37(9):2841-53. PubMed ID: 19282454
    [Abstract] [Full Text] [Related]

  • 3. Role of Poly [ADP-ribose] Polymerase 1 in Activating the Kirsten ras (KRAS) Gene in Response to Oxidative Stress.
    Cinque G, Ferino A, Pedersen EB, Xodo LE.
    Int J Mol Sci; 2020 Aug 28; 21(17):. PubMed ID: 32872305
    [Abstract] [Full Text] [Related]

  • 4. Regulation of oncogenic KRAS signaling via a novel KRAS-integrin-linked kinase-hnRNPA1 regulatory loop in human pancreatic cancer cells.
    Chu PC, Yang MC, Kulp SK, Salunke SB, Himmel LE, Fang CS, Jadhav AM, Shan YS, Lee CT, Lai MD, Shirley LA, Bekaii-Saab T, Chen CS.
    Oncogene; 2016 Jul 28; 35(30):3897-908. PubMed ID: 26616862
    [Abstract] [Full Text] [Related]

  • 5. The regulatory G4 motif of the Kirsten ras (KRAS) gene is sensitive to guanine oxidation: implications on transcription.
    Cogoi S, Ferino A, Miglietta G, Pedersen EB, Xodo LE.
    Nucleic Acids Res; 2018 Jan 25; 46(2):661-676. PubMed ID: 29165690
    [Abstract] [Full Text] [Related]

  • 6. Protein hnRNPA1 binds to a critical G-rich element of KRAS and unwinds G-quadruplex structures: implications in transcription.
    Xodo L, Paramasivam M, Membrino A, Cogoi S.
    Nucleic Acids Symp Ser (Oxf); 2008 Jan 25; (52):159-60. PubMed ID: 18776302
    [Abstract] [Full Text] [Related]

  • 7. G-quadruplexes in human promoters: A challenge for therapeutic applications.
    Rigo R, Palumbo M, Sissi C.
    Biochim Biophys Acta Gen Subj; 2017 May 25; 1861(5 Pt B):1399-1413. PubMed ID: 28025083
    [Abstract] [Full Text] [Related]

  • 8. Tandem application of ligand-based virtual screening and G4-OAS assay to identify novel G-quadruplex-targeting chemotypes.
    Musumeci D, Amato J, Zizza P, Platella C, Cosconati S, Cingolani C, Biroccio A, Novellino E, Randazzo A, Giancola C, Pagano B, Montesarchio D.
    Biochim Biophys Acta Gen Subj; 2017 May 25; 1861(5 Pt B):1341-1352. PubMed ID: 28130159
    [Abstract] [Full Text] [Related]

  • 9. Ribonucleoprotein HNRNPA2B1 interacts with and regulates oncogenic KRAS in pancreatic ductal adenocarcinoma cells.
    Barceló C, Etchin J, Mansour MR, Sanda T, Ginesta MM, Sanchez-Arévalo Lobo VJ, Real FX, Capellà G, Estanyol JM, Jaumot M, Look AT, Agell N.
    Gastroenterology; 2014 Oct 25; 147(4):882-892.e8. PubMed ID: 24998203
    [Abstract] [Full Text] [Related]

  • 10. Phenanthroline-bis-oxazole ligands for binding and stabilization of G-quadruplexes.
    Medeiros-Silva J, Guédin A, Salgado GF, Mergny JL, Queiroz JA, Cabrita EJ, Cruz C.
    Biochim Biophys Acta Gen Subj; 2017 May 25; 1861(5 Pt B):1281-1292. PubMed ID: 27865994
    [Abstract] [Full Text] [Related]

  • 11. The human AP-endonuclease 1 (APE1) is a DNA G-quadruplex structure binding protein and regulates KRAS expression in pancreatic ductal adenocarcinoma cells.
    Pramanik S, Chen Y, Song H, Khutsishvili I, Marky LA, Ray S, Natarajan A, Singh PK, Bhakat KK.
    Nucleic Acids Res; 2022 Apr 08; 50(6):3394-3412. PubMed ID: 35286386
    [Abstract] [Full Text] [Related]

  • 12. EMICORON: A multi-targeting G4 ligand with a promising preclinical profile.
    Porru M, Zizza P, Franceschin M, Leonetti C, Biroccio A.
    Biochim Biophys Acta Gen Subj; 2017 May 08; 1861(5 Pt B):1362-1370. PubMed ID: 27838395
    [Abstract] [Full Text] [Related]

  • 13. MAZ-binding G4-decoy with locked nucleic acid and twisted intercalating nucleic acid modifications suppresses KRAS in pancreatic cancer cells and delays tumor growth in mice.
    Cogoi S, Zorzet S, Rapozzi V, Géci I, Pedersen EB, Xodo LE.
    Nucleic Acids Res; 2013 Apr 08; 41(7):4049-64. PubMed ID: 23471001
    [Abstract] [Full Text] [Related]

  • 14. Discovery of the first dual G-triplex/G-quadruplex stabilizing compound: a new opportunity in the targeting of G-rich DNA structures?
    Amato J, Pagano A, Cosconati S, Amendola G, Fotticchia I, Iaccarino N, Marinello J, De Magis A, Capranico G, Novellino E, Pagano B, Randazzo A.
    Biochim Biophys Acta Gen Subj; 2017 May 08; 1861(5 Pt B):1271-1280. PubMed ID: 27836755
    [Abstract] [Full Text] [Related]

  • 15. The cellular protein nucleolin preferentially binds long-looped G-quadruplex nucleic acids.
    Lago S, Tosoni E, Nadai M, Palumbo M, Richter SN.
    Biochim Biophys Acta Gen Subj; 2017 May 08; 1861(5 Pt B):1371-1381. PubMed ID: 27913192
    [Abstract] [Full Text] [Related]

  • 16. Targeting integrin-linked kinase to suppress oncogenic KRAS signaling in pancreatic cancer.
    Chu PC, Kulp SK, Bekaii-Saab T, Chen CS.
    Small GTPases; 2018 Nov 02; 9(6):452-456. PubMed ID: 27936345
    [Abstract] [Full Text] [Related]

  • 17. Real-time and quantitative fluorescent live-cell imaging with quadruplex-specific red-edge probe (G4-REP).
    Yang SY, Amor S, Laguerre A, Wong JMY, Monchaud D.
    Biochim Biophys Acta Gen Subj; 2017 May 02; 1861(5 Pt B):1312-1320. PubMed ID: 27956241
    [Abstract] [Full Text] [Related]

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  • 19. Insight into the Complexity of the i-Motif and G-Quadruplex DNA Structures Formed in the KRAS Promoter and Subsequent Drug-Induced Gene Repression.
    Kaiser CE, Van Ert NA, Agrawal P, Chawla R, Yang D, Hurley LH.
    J Am Chem Soc; 2017 Jun 28; 139(25):8522-8536. PubMed ID: 28570076
    [Abstract] [Full Text] [Related]

  • 20. Identification and characterization of a new G-quadruplex forming region within the kRAS promoter as a transcriptional regulator.
    Morgan RK, Batra H, Gaerig VC, Hockings J, Brooks TA.
    Biochim Biophys Acta; 2016 Feb 28; 1859(2):235-45. PubMed ID: 26597160
    [Abstract] [Full Text] [Related]

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