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Journal Abstract Search

542 related items for PubMed ID: 27896399

  • 1. Cytochrome P450-mediated metabolism of triclosan attenuates its cytotoxicity in hepatic cells.
    Wu Y, Chitranshi P, Loukotková L, Gamboa da Costa G, Beland FA, Zhang J, Fang JL.
    Arch Toxicol; 2017 Jun; 91(6):2405-2423. PubMed ID: 27896399
    [Abstract] [Full Text] [Related]

  • 2. Direct comparison of UDP-glucuronosyltransferase and cytochrome P450 activities in human liver microsomes, plated and suspended primary human hepatocytes from five liver donors.
    den Braver-Sewradj SP, den Braver MW, Baze A, Decorde J, Fonsi M, Bachellier P, Vermeulen NPE, Commandeur JNM, Richert L, Vos JC.
    Eur J Pharm Sci; 2017 Nov 15; 109():96-110. PubMed ID: 28778465
    [Abstract] [Full Text] [Related]

  • 3. Metabolism-mediated drug interaction potential of HS-23, a new herbal drug for the treatment of sepsis in human hepatocytes and liver microsomes.
    Jeong HU, Lee JY, Kwon SS, Kim JH, Kim YM, Hong SW, Yeon SH, Lee SM, Cho YY, Lee HS.
    Arch Pharm Res; 2015 Feb 15; 38(2):171-7. PubMed ID: 25052959
    [Abstract] [Full Text] [Related]

  • 4. Rapid determination of enzyme activities of recombinant human cytochromes P450, human liver microsomes and hepatocytes.
    Ghosal A, Hapangama N, Yuan Y, Lu X, Horne D, Patrick JE, Zbaida S.
    Biopharm Drug Dispos; 2003 Dec 15; 24(9):375-84. PubMed ID: 14689466
    [Abstract] [Full Text] [Related]

  • 5. Comparison of Drug Metabolism and Its Related Hepatotoxic Effects in HepaRG, Cryopreserved Human Hepatocytes, and HepG2 Cell Cultures.
    Yokoyama Y, Sasaki Y, Terasaki N, Kawataki T, Takekawa K, Iwase Y, Shimizu T, Sanoh S, Ohta S.
    Biol Pharm Bull; 2018 May 01; 41(5):722-732. PubMed ID: 29445054
    [Abstract] [Full Text] [Related]

  • 6. Contribution of CYP2C9, CYP2A6, and CYP2B6 to valproic acid metabolism in hepatic microsomes from individuals with the CYP2C9*1/*1 genotype.
    Kiang TK, Ho PC, Anari MR, Tong V, Abbott FS, Chang TK.
    Toxicol Sci; 2006 Dec 01; 94(2):261-71. PubMed ID: 16945988
    [Abstract] [Full Text] [Related]

  • 7. Ethanol oxidation into acetaldehyde by 16 recombinant human cytochrome P450 isoforms: role of CYP2C isoforms in human liver microsomes.
    Hamitouche S, Poupon J, Dreano Y, Amet Y, Lucas D.
    Toxicol Lett; 2006 Dec 15; 167(3):221-30. PubMed ID: 17084997
    [Abstract] [Full Text] [Related]

  • 8. Establishment of the transformants expressing human cytochrome P450 subtypes in HepG2, and their applications on drug metabolism and toxicology.
    Yoshitomi S, Ikemoto K, Takahashi J, Miki H, Namba M, Asahi S.
    Toxicol In Vitro; 2001 Jun 15; 15(3):245-56. PubMed ID: 11377097
    [Abstract] [Full Text] [Related]

  • 9. The effects of gender, age, ethnicity, and liver cirrhosis on cytochrome P450 enzyme activity in human liver microsomes and inducibility in cultured human hepatocytes.
    Parkinson A, Mudra DR, Johnson C, Dwyer A, Carroll KM.
    Toxicol Appl Pharmacol; 2004 Sep 15; 199(3):193-209. PubMed ID: 15364537
    [Abstract] [Full Text] [Related]

  • 10. Delamanid does not inhibit or induce cytochrome p450 enzymes in vitro.
    Shimokawa Y, Sasahara K, Yoda N, Mizuno K, Umehara K.
    Biol Pharm Bull; 2014 Sep 15; 37(11):1727-35. PubMed ID: 25366478
    [Abstract] [Full Text] [Related]

  • 11. Charactering the metabolism of cryptotanshinone by human P450 enzymes and uridine diphosphate glucuronosyltransferases in vitro.
    Zeng J, Fan YJ, Tan B, Su HZ, Li Y, Zhang LL, Jiang J, Qiu FR.
    Acta Pharmacol Sin; 2018 Aug 15; 39(8):1393-1404. PubMed ID: 29417949
    [Abstract] [Full Text] [Related]

  • 12. In vitro effects of 95% khat ethanol extract (KEE) on human recombinant cytochrome P450 (CYP)1A2, CYP2A6, CYP2B6, CYP2C8, CYP2C19, CYP2E1, CYP2J2 and CYP3A5.
    Lim SYM, Alshagga MA, Alshawsh MA, Ong CE, Pan Y.
    Drug Metab Pers Ther; 2021 Aug 17; 37(1):55-67. PubMed ID: 35146975
    [Abstract] [Full Text] [Related]

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  • 15. Distinction between human cytochrome P450 (CYP) isoforms and identification of new phosphorylation sites by mass spectrometry.
    Redlich G, Zanger UM, Riedmaier S, Bache N, Giessing AB, Eisenacher M, Stephan C, Meyer HE, Jensen ON, Marcus K.
    J Proteome Res; 2008 Nov 17; 7(11):4678-88. PubMed ID: 18828626
    [Abstract] [Full Text] [Related]

  • 16. In vitro metabolism of nobiletin, a polymethoxy-flavonoid, by human liver microsomes and cytochrome P450.
    Koga N, Ohta C, Kato Y, Haraguchi K, Endo T, Ogawa K, Ohta H, Yano M.
    Xenobiotica; 2011 Nov 17; 41(11):927-33. PubMed ID: 21726170
    [Abstract] [Full Text] [Related]

  • 17. Elucidation of individual cytochrome P450 enzymes involved in the metabolism of clozapine.
    Fang J, Coutts RT, McKenna KF, Baker GB.
    Naunyn Schmiedebergs Arch Pharmacol; 1998 Nov 17; 358(5):592-9. PubMed ID: 9840430
    [Abstract] [Full Text] [Related]

  • 18. Effect of honokiol on the induction of drug-metabolizing enzymes in human hepatocytes.
    Cho YY, Jeong HU, Kim JH, Lee HS.
    Drug Des Devel Ther; 2014 Nov 17; 8():2137-45. PubMed ID: 25395831
    [Abstract] [Full Text] [Related]

  • 19. Absolute protein quantification of clinically relevant cytochrome P450 enzymes and UDP-glucuronosyltransferases by mass spectrometry-based targeted proteomics.
    Gröer C, Busch D, Patrzyk M, Beyer K, Busemann A, Heidecke CD, Drozdzik M, Siegmund W, Oswald S.
    J Pharm Biomed Anal; 2014 Nov 17; 100():393-401. PubMed ID: 25218440
    [Abstract] [Full Text] [Related]

  • 20. The role of human CYP2C8 and CYP2C9 variants in pioglitazone metabolism in vitro.
    Muschler E, Lal J, Jetter A, Rattay A, Zanger U, Zadoyan G, Fuhr U, Kirchheiner J.
    Basic Clin Pharmacol Toxicol; 2009 Dec 17; 105(6):374-9. PubMed ID: 19614891
    [Abstract] [Full Text] [Related]

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