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Journal Abstract Search

409 related items for PubMed ID: 27908752

  • 1. N-Propargylpiperidines with naphthalene-2-carboxamide or naphthalene-2-sulfonamide moieties: Potential multifunctional anti-Alzheimer's agents.
    Košak U, Knez D, Coquelle N, Brus B, Pišlar A, Nachon F, Brazzolotto X, Kos J, Colletier JP, Gobec S.
    Bioorg Med Chem; 2017 Jan 15; 25(2):633-645. PubMed ID: 27908752
    [Abstract] [Full Text] [Related]

  • 2. N-alkylpiperidine carbamates as potential anti-Alzheimer's agents.
    Košak U, Strašek N, Knez D, Jukič M, Žakelj S, Zahirović A, Pišlar A, Brazzolotto X, Nachon F, Kos J, Gobec S.
    Eur J Med Chem; 2020 Jul 01; 197():112282. PubMed ID: 32380361
    [Abstract] [Full Text] [Related]

  • 3. Design, synthesis, in-silico and biological evaluation of novel chalcone-O-carbamate derivatives as multifunctional agents for the treatment of Alzheimer's disease.
    Sang Z, Wang K, Shi J, Liu W, Tan Z.
    Eur J Med Chem; 2019 Sep 15; 178():726-739. PubMed ID: 31229875
    [Abstract] [Full Text] [Related]

  • 4. Synthesis, biological evaluation, and molecular modeling of donepezil and N-[(5-(benzyloxy)-1-methyl-1H-indol-2-yl)methyl]-N-methylprop-2-yn-1-amine hybrids as new multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease.
    Bolea I, Juárez-Jiménez J, de Los Ríos C, Chioua M, Pouplana R, Luque FJ, Unzeta M, Marco-Contelles J, Samadi A.
    J Med Chem; 2011 Dec 22; 54(24):8251-70. PubMed ID: 22023459
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and pharmacological evaluation of donepezil-based agents as new cholinesterase/monoamine oxidase inhibitors for the potential application against Alzheimer's disease.
    Li F, Wang ZM, Wu JJ, Wang J, Xie SS, Lan JS, Xu W, Kong LY, Wang XB.
    J Enzyme Inhib Med Chem; 2016 Dec 22; 31(sup3):41-53. PubMed ID: 27384289
    [Abstract] [Full Text] [Related]

  • 6. Design, synthesis, and in vitro evaluation of 4-aminoalkyl-1(2H)-phthalazinones as potential multifunctional anti-Alzheimer's disease agents.
    Ye C, Xu R, Cao Z, Song Q, Yu G, Shi Y, Liu Z, Liu X, Deng Y.
    Bioorg Chem; 2021 Jun 22; 111():104895. PubMed ID: 33887586
    [Abstract] [Full Text] [Related]

  • 7. Design, synthesis and evaluation of cinnamic acid hybrids as multi-target-directed agents for the treatment of Alzheimer's disease.
    Wang K, Shi J, Zhou Y, He Y, Mi J, Yang J, Liu S, Tang X, Liu W, Tan Z, Sang Z.
    Bioorg Chem; 2021 Jul 22; 112():104879. PubMed ID: 33915461
    [Abstract] [Full Text] [Related]

  • 8. Scouting around 1,2,3,4-Tetrahydrochromeno[3,2-c]pyridin-10-ones for Single- and Multitarget Ligands Directed towards Relevant Alzheimer's Targets.
    Purgatorio R, Kulikova LN, Pisani L, Catto M, de Candia M, Carrieri A, Cellamare S, De Palma A, Beloglazkin AA, Reza Raesi G, Voskressensky LG, Altomare CD.
    ChemMedChem; 2020 Oct 19; 15(20):1947-1955. PubMed ID: 32716595
    [Abstract] [Full Text] [Related]

  • 9. Flurbiprofen-chalcone hybrid Mannich base derivatives as balanced multifunctional agents against Alzheimer's disease: Design, synthesis and biological evaluation.
    Tian C, Qiang X, Song Q, Cao Z, Ye C, He Y, Deng Y, Zhang L.
    Bioorg Chem; 2020 Jan 19; 94():103477. PubMed ID: 31818478
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and evaluation of 7-substituted coumarin derivatives as multimodal monoamine oxidase-B and cholinesterase inhibitors for the treatment of Alzheimer's disease.
    Joubert J, Foka GB, Repsold BP, Oliver DW, Kapp E, Malan SF.
    Eur J Med Chem; 2017 Jan 05; 125():853-864. PubMed ID: 27744252
    [Abstract] [Full Text] [Related]

  • 11. Discovery of novel propargylamine-modified 4-aminoalkyl imidazole substituted pyrimidinylthiourea derivatives as multifunctional agents for the treatment of Alzheimer's disease.
    Xu YX, Wang H, Li XK, Dong SN, Liu WW, Gong Q, Wang TD, Tang Y, Zhu J, Li J, Zhang HY, Mao F.
    Eur J Med Chem; 2018 Jan 01; 143():33-47. PubMed ID: 29172081
    [Abstract] [Full Text] [Related]

  • 12. Design, synthesis and biological evaluation of rasagiline-clorgyline hybrids as novel dual inhibitors of monoamine oxidase-B and amyloid-β aggregation against Alzheimer's disease.
    Xie SS, Liu J, Tang C, Pang C, Li Q, Qin Y, Nong X, Zhang Z, Guo J, Cheng M, Tang W, Liang N, Jiang N.
    Eur J Med Chem; 2020 Sep 15; 202():112475. PubMed ID: 32652406
    [Abstract] [Full Text] [Related]

  • 13. Design, synthesis and evaluation of chalcone Mannich base derivatives as multifunctional agents for the potential treatment of Alzheimer's disease.
    Zhang X, Song Q, Cao Z, Li Y, Tian C, Yang Z, Zhang H, Deng Y.
    Bioorg Chem; 2019 Jun 15; 87():395-408. PubMed ID: 30921741
    [Abstract] [Full Text] [Related]

  • 14. Synthesis of Amide and Ester Derivatives of Cinnamic Acid and Its Analogs: Evaluation of Their Free Radical Scavenging and Monoamine Oxidase and Cholinesterase Inhibitory Activities.
    Takao K, Toda K, Saito T, Sugita Y.
    Chem Pharm Bull (Tokyo); 2017 Jun 15; 65(11):1020-1027. PubMed ID: 29093288
    [Abstract] [Full Text] [Related]

  • 15. Cyanobiphenyls: Novel H3 receptor ligands with cholinesterase and MAO B inhibitory activity as multitarget compounds for potential treatment of Alzheimer's disease.
    Godyń J, Zaręba P, Łażewska D, Stary D, Reiner-Link D, Frank A, Latacz G, Mogilski S, Kaleta M, Doroz-Płonka A, Lubelska A, Honkisz-Orzechowska E, Olejarz-Maciej A, Handzlik J, Stark H, Kieć-Kononowicz K, Malawska B, Bajda M.
    Bioorg Chem; 2021 Sep 15; 114():105129. PubMed ID: 34217977
    [Abstract] [Full Text] [Related]

  • 16. Isoquinoline alkaloids from the roots of Zanthoxylum rigidum as multi-target inhibitors of cholinesterase, monoamine oxidase A and Aβ1-42 aggregation.
    Plazas E, Hagenow S, Avila Murillo M, Stark H, Cuca LE.
    Bioorg Chem; 2020 May 15; 98():103722. PubMed ID: 32155491
    [Abstract] [Full Text] [Related]

  • 17. Design, synthesis, in-silico and biological evaluation of novel chalcone derivatives as multi-function agents for the treatment of Alzheimer's disease.
    Sang Z, Wang K, Zhang P, Shi J, Liu W, Tan Z.
    Eur J Med Chem; 2019 Oct 15; 180():238-252. PubMed ID: 31310916
    [Abstract] [Full Text] [Related]

  • 18. Design, synthesis and biological evaluation of novel coumarin-N-benzyl pyridinium hybrids as multi-target agents for the treatment of Alzheimer's disease.
    Lan JS, Ding Y, Liu Y, Kang P, Hou JW, Zhang XY, Xie SS, Zhang T.
    Eur J Med Chem; 2017 Oct 20; 139():48-59. PubMed ID: 28797883
    [Abstract] [Full Text] [Related]

  • 19. Multipotent MAO and cholinesterase inhibitors for the treatment of Alzheimer's disease: synthesis, pharmacological analysis and molecular modeling of heterocyclic substituted alkyl and cycloalkyl propargyl amine.
    Samadi A, de los Ríos C, Bolea I, Chioua M, Iriepa I, Moraleda I, Bartolini M, Andrisano V, Gálvez E, Valderas C, Unzeta M, Marco-Contelles J.
    Eur J Med Chem; 2012 Jun 20; 52():251-62. PubMed ID: 22503231
    [Abstract] [Full Text] [Related]

  • 20. Design, synthesis and biological evaluation of 3,4-dihydro-2(1H)-quinoline-O-alkylamine derivatives as new multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease.
    Sang Z, Pan W, Wang K, Ma Q, Yu L, Liu W.
    Bioorg Med Chem; 2017 Jun 15; 25(12):3006-3017. PubMed ID: 28487125
    [Abstract] [Full Text] [Related]

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