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151 related items for PubMed ID: 27921176

  • 1. Two Feet on the Membrane: Uptake of Clostridial Neurotoxins.
    Rummel A.
    Curr Top Microbiol Immunol; 2017; 406():1-37. PubMed ID: 27921176
    [Abstract] [Full Text] [Related]

  • 2. Double receptor anchorage of botulinum neurotoxins accounts for their exquisite neurospecificity.
    Rummel A.
    Curr Top Microbiol Immunol; 2013; 364():61-90. PubMed ID: 23239349
    [Abstract] [Full Text] [Related]

  • 3. Only the complex N559-glycan in the synaptic vesicle glycoprotein 2C mediates high affinity binding to botulinum neurotoxin serotype A1.
    Mahrhold S, Bergström T, Stern D, Dorner BG, Åstot C, Rummel A.
    Biochem J; 2016 Sep 01; 473(17):2645-54. PubMed ID: 27313224
    [Abstract] [Full Text] [Related]

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  • 5. Botulinum neurotoxins C, E and F bind gangliosides via a conserved binding site prior to stimulation-dependent uptake with botulinum neurotoxin F utilising the three isoforms of SV2 as second receptor.
    Rummel A, Häfner K, Mahrhold S, Darashchonak N, Holt M, Jahn R, Beermann S, Karnath T, Bigalke H, Binz T.
    J Neurochem; 2009 Sep 01; 110(6):1942-54. PubMed ID: 19650874
    [Abstract] [Full Text] [Related]

  • 6. Tetanus toxin and botulinum toxin a utilize unique mechanisms to enter neurons of the central nervous system.
    Blum FC, Chen C, Kroken AR, Barbieri JT.
    Infect Immun; 2012 May 01; 80(5):1662-9. PubMed ID: 22392932
    [Abstract] [Full Text] [Related]

  • 7. Identification of the SV2 protein receptor-binding site of botulinum neurotoxin type E.
    Mahrhold S, Strotmeier J, Garcia-Rodriguez C, Lou J, Marks JD, Rummel A, Binz T.
    Biochem J; 2013 Jul 01; 453(1):37-47. PubMed ID: 23621114
    [Abstract] [Full Text] [Related]

  • 8. Glycosylated SV2 and gangliosides as dual receptors for botulinum neurotoxin serotype F.
    Fu Z, Chen C, Barbieri JT, Kim JJ, Baldwin MR.
    Biochemistry; 2009 Jun 23; 48(24):5631-41. PubMed ID: 19476346
    [Abstract] [Full Text] [Related]

  • 9. Botulinum neurotoxin serotype D attacks neurons via two carbohydrate-binding sites in a ganglioside-dependent manner.
    Strotmeier J, Lee K, Völker AK, Mahrhold S, Zong Y, Zeiser J, Zhou J, Pich A, Bigalke H, Binz T, Rummel A, Jin R.
    Biochem J; 2010 Oct 15; 431(2):207-16. PubMed ID: 20704566
    [Abstract] [Full Text] [Related]

  • 10. Exchanging the minimal cell binding fragments of tetanus neurotoxin in botulinum neurotoxin A and B impacts their toxicity at the neuromuscular junction and central neurons.
    Höltje M, Schulze S, Strotmeier J, Mahrhold S, Richter K, Binz T, Bigalke H, Ahnert-Hilger G, Rummel A.
    Toxicon; 2013 Dec 01; 75():108-21. PubMed ID: 23817019
    [Abstract] [Full Text] [Related]

  • 11. Structural basis of botulinum neurotoxin serotype A1 binding to human SV2A or SV2C receptors.
    Azzaz F, Hilaire D, Fantini J.
    Chem Biol Interact; 2023 Mar 01; 373():110384. PubMed ID: 36754227
    [Abstract] [Full Text] [Related]

  • 12. Cell entry strategy of clostridial neurotoxins.
    Binz T, Rummel A.
    J Neurochem; 2009 Jun 01; 109(6):1584-95. PubMed ID: 19457120
    [Abstract] [Full Text] [Related]

  • 13. The 25 kDa HCN Domain of Clostridial Neurotoxins Is Indispensable for Their Neurotoxicity.
    Deppe J, Weisemann J, Mahrhold S, Rummel A.
    Toxins (Basel); 2020 Nov 26; 12(12):. PubMed ID: 33255952
    [Abstract] [Full Text] [Related]

  • 14. The travel diaries of tetanus and botulinum neurotoxins.
    Surana S, Tosolini AP, Meyer IFG, Fellows AD, Novoselov SS, Schiavo G.
    Toxicon; 2018 Jun 01; 147():58-67. PubMed ID: 29031941
    [Abstract] [Full Text] [Related]

  • 15. Botulinum neurotoxin D uses synaptic vesicle protein SV2 and gangliosides as receptors.
    Peng L, Tepp WH, Johnson EA, Dong M.
    PLoS Pathog; 2011 Mar 01; 7(3):e1002008. PubMed ID: 21483489
    [Abstract] [Full Text] [Related]

  • 16. Uptake of Clostridial Neurotoxins into Cells and Dissemination.
    Connan C, Popoff MR.
    Curr Top Microbiol Immunol; 2017 Mar 01; 406():39-78. PubMed ID: 28879524
    [Abstract] [Full Text] [Related]

  • 17. Association of botulinum neurotoxins with synaptic vesicle protein complexes.
    Baldwin MR, Barbieri JT.
    Toxicon; 2009 Oct 01; 54(5):570-4. PubMed ID: 19362106
    [Abstract] [Full Text] [Related]

  • 18. Botulinum neurotoxin G binds synaptotagmin-II in a mode similar to that of serotype B: tyrosine 1186 and lysine 1191 cause its lower affinity.
    Willjes G, Mahrhold S, Strotmeier J, Eichner T, Rummel A, Binz T.
    Biochemistry; 2013 Jun 04; 52(22):3930-8. PubMed ID: 23647335
    [Abstract] [Full Text] [Related]

  • 19. Botulinum neurotoxins A and E undergo retrograde axonal transport in primary motor neurons.
    Restani L, Giribaldi F, Manich M, Bercsenyi K, Menendez G, Rossetto O, Caleo M, Schiavo G.
    PLoS Pathog; 2012 Dec 04; 8(12):e1003087. PubMed ID: 23300443
    [Abstract] [Full Text] [Related]

  • 20. Glycosylated SV2A and SV2B mediate the entry of botulinum neurotoxin E into neurons.
    Dong M, Liu H, Tepp WH, Johnson EA, Janz R, Chapman ER.
    Mol Biol Cell; 2008 Dec 04; 19(12):5226-37. PubMed ID: 18815274
    [Abstract] [Full Text] [Related]


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