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Journal Abstract Search

241 related items for PubMed ID: 27923639

  • 1. Disruption of a putative intersubunit electrostatic bond enhances agonist efficacy at the human α1 glycine receptor.
    Welsh BT, Todorovic J, Kirson D, Allen HM, Bayly MD, Mihic SJ.
    Brain Res; 2017 Feb 15; 1657():148-155. PubMed ID: 27923639
    [Abstract] [Full Text] [Related]

  • 2. Disruption of an intersubunit electrostatic bond is a critical step in glycine receptor activation.
    Todorovic J, Welsh BT, Bertaccini EJ, Trudell JR, Mihic SJ.
    Proc Natl Acad Sci U S A; 2010 Apr 27; 107(17):7987-92. PubMed ID: 20385800
    [Abstract] [Full Text] [Related]

  • 3. A novel domain of the inhibitory glycine receptor determining antagonist efficacies: further evidence for partial agonism resulting from self-inhibition.
    Schmieden V, Kuhse J, Betz H.
    Mol Pharmacol; 1999 Sep 27; 56(3):464-72. PubMed ID: 10462533
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  • 4. Allosteric modulation of the glycine receptor activated by agonists differing in efficacy.
    Farley NM, Mihic SJ.
    Brain Res; 2015 May 05; 1606():95-101. PubMed ID: 25721789
    [Abstract] [Full Text] [Related]

  • 5. Comparison of taurine- and glycine-induced conformational changes in the M2-M3 domain of the glycine receptor.
    Han NL, Clements JD, Lynch JW.
    J Biol Chem; 2004 May 07; 279(19):19559-65. PubMed ID: 14981077
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  • 6. Differential agonist sensitivity of glycine receptor alpha2 subunit splice variants.
    Miller PS, Harvey RJ, Smart TG.
    Br J Pharmacol; 2004 Sep 07; 143(1):19-26. PubMed ID: 15302677
    [Abstract] [Full Text] [Related]

  • 7. Distinct conformational changes in activated agonist-bound and agonist-free glycine receptor subunits.
    Pless SA, Lynch JW.
    J Neurochem; 2009 Mar 07; 108(6):1585-94. PubMed ID: 19166513
    [Abstract] [Full Text] [Related]

  • 8. Hyperekplexia mutations of the glycine receptor unmask the inhibitory subsite for beta-amino-acids.
    Laube B, Langosch D, Betz H, Schmieden V.
    Neuroreport; 1995 Apr 19; 6(6):897-900. PubMed ID: 7542038
    [Abstract] [Full Text] [Related]

  • 9. Probing the pharmacological properties of distinct subunit interfaces within heteromeric glycine receptors reveals a functional ββ agonist-binding site.
    Dutertre S, Drwal M, Laube B, Betz H.
    J Neurochem; 2012 Jul 19; 122(1):38-47. PubMed ID: 22486198
    [Abstract] [Full Text] [Related]

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  • 11. Ethanol enhances taurine-activated glycine receptor function.
    Welsh BT, Kirson D, Allen HM, Mihic SJ.
    Alcohol Clin Exp Res; 2010 Sep 01; 34(9):1634-9. PubMed ID: 20586750
    [Abstract] [Full Text] [Related]

  • 12. Pharmacology of the inhibitory glycine receptor: agonist and antagonist actions of amino acids and piperidine carboxylic acid compounds.
    Schmieden V, Betz H.
    Mol Pharmacol; 1995 Nov 01; 48(5):919-27. PubMed ID: 7476923
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  • 14. The Startle Disease Mutation E103K Impairs Activation of Human Homomeric α1 Glycine Receptors by Disrupting an Intersubunit Salt Bridge across the Agonist Binding Site.
    Safar F, Hurdiss E, Erotocritou M, Greiner T, Lape R, Irvine MW, Fang G, Jane D, Yu R, Dämgen MA, Biggin PC, Sivilotti LG.
    J Biol Chem; 2017 Mar 24; 292(12):5031-5042. PubMed ID: 28174298
    [Abstract] [Full Text] [Related]

  • 15. Positive allosteric modulators differentially affect full versus partial agonist activation of the glycine receptor.
    Kirson D, Todorovic J, Mihic SJ.
    J Pharmacol Exp Ther; 2012 Jul 24; 342(1):61-70. PubMed ID: 22473615
    [Abstract] [Full Text] [Related]

  • 16. Characterization of a glycine receptor domain that controls the binding and gating mechanisms of the beta-amino acid agonist, taurine.
    Han NL, Haddrill JL, Lynch JW.
    J Neurochem; 2001 Nov 24; 79(3):636-47. PubMed ID: 11701767
    [Abstract] [Full Text] [Related]

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  • 19. Charge and geometry of residues in the loop 2 β hairpin differentially affect agonist and ethanol sensitivity in glycine receptors.
    Perkins DI, Trudell JR, Asatryan L, Davies DL, Alkana RL.
    J Pharmacol Exp Ther; 2012 May 24; 341(2):543-51. PubMed ID: 22357974
    [Abstract] [Full Text] [Related]

  • 20. The intracellular domain of homomeric glycine receptors modulates agonist efficacy.
    Ivica J, Lape R, Jazbec V, Yu J, Zhu H, Gouaux E, Gold MG, Sivilotti LG.
    J Biol Chem; 2021 May 24; 296():100387. PubMed ID: 33617876
    [Abstract] [Full Text] [Related]

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