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241 related items for PubMed ID: 27923639

  • 21. Different binding modes of tropeines mediating inhibition and potentiation of alpha1 glycine receptors.
    Maksay G, Laube B, Schemm R, Grudzinska J, Drwal M, Betz H.
    J Neurochem; 2009 Jun; 109(6):1725-32. PubMed ID: 19383091
    [Abstract] [Full Text] [Related]

  • 22. Mutation of glycine receptor subunit creates beta-alanine receptor responsive to GABA.
    Schmieden V, Kuhse J, Betz H.
    Science; 1993 Oct 08; 262(5131):256-8. PubMed ID: 8211147
    [Abstract] [Full Text] [Related]

  • 23. Activation of human alpha1 and alpha2 homomeric glycine receptors by taurine and GABA.
    De Saint Jan D, David-Watine B, Korn H, Bregestovski P.
    J Physiol; 2001 Sep 15; 535(Pt 3):741-55. PubMed ID: 11559772
    [Abstract] [Full Text] [Related]

  • 24. Ethanol Modulation is Quantitatively Determined by the Transmembrane Domain of Human α1 Glycine Receptors.
    Horani S, Stater EP, Corringer PJ, Trudell JR, Harris RA, Howard RJ.
    Alcohol Clin Exp Res; 2015 Jun 15; 39(6):962-8. PubMed ID: 25973519
    [Abstract] [Full Text] [Related]

  • 25. Conformational variability of the glycine receptor M2 domain in response to activation by different agonists.
    Pless SA, Dibas MI, Lester HA, Lynch JW.
    J Biol Chem; 2007 Dec 07; 282(49):36057-67. PubMed ID: 17911099
    [Abstract] [Full Text] [Related]

  • 26. Magnitude of a conformational change in the glycine receptor beta1-beta2 loop is correlated with agonist efficacy.
    Pless SA, Lynch JW.
    J Biol Chem; 2009 Oct 02; 284(40):27370-6. PubMed ID: 19643731
    [Abstract] [Full Text] [Related]

  • 27. Single Channel Analysis of Isoflurane and Ethanol Enhancement of Taurine-Activated Glycine Receptors.
    Kirson D, Todorovic J, Mihic SJ.
    J Pharmacol Exp Ther; 2018 Jan 02; 364(1):70-76. PubMed ID: 29118035
    [Abstract] [Full Text] [Related]

  • 28. Mechanism of gating and partial agonist action in the glycine receptor.
    Yu J, Zhu H, Lape R, Greiner T, Du J, Lü W, Sivilotti L, Gouaux E.
    Cell; 2021 Feb 18; 184(4):957-968.e21. PubMed ID: 33567265
    [Abstract] [Full Text] [Related]

  • 29. Manipulations of extracellular Loop 2 in α1 GlyR ultra-sensitive ethanol receptors (USERs) enhance receptor sensitivity to isoflurane, ethanol, and lidocaine, but not propofol.
    Naito A, Muchhala KH, Trang J, Asatryan L, Trudell JR, Homanics GE, Alkana RL, Davies DL.
    Neuroscience; 2015 Jun 25; 297():68-77. PubMed ID: 25827497
    [Abstract] [Full Text] [Related]

  • 30. Mutation of an arginine residue in the human glycine receptor transforms beta-alanine and taurine from agonists into competitive antagonists.
    Rajendra S, Lynch JW, Pierce KD, French CR, Barry PH, Schofield PR.
    Neuron; 1995 Jan 25; 14(1):169-75. PubMed ID: 7826634
    [Abstract] [Full Text] [Related]

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  • 32. The startle disease mutation Q266H, in the second transmembrane domain of the human glycine receptor, impairs channel gating.
    Moorhouse AJ, Jacques P, Barry PH, Schofield PR.
    Mol Pharmacol; 1999 Feb 25; 55(2):386-95. PubMed ID: 9927632
    [Abstract] [Full Text] [Related]

  • 33. Correlating structural and energetic changes in glycine receptor activation.
    Scott S, Lynch JW, Keramidas A.
    J Biol Chem; 2015 Feb 27; 290(9):5621-34. PubMed ID: 25572390
    [Abstract] [Full Text] [Related]

  • 34. Disruption of a Structurally Important Extracellular Element in the Glycine Receptor Leads to Decreased Synaptic Integration and Signaling Resulting in Severe Startle Disease.
    Schaefer N, Berger A, van Brederode J, Zheng F, Zhang Y, Leacock S, Littau L, Jablonka S, Malhotra S, Topf M, Winter F, Davydova D, Lynch JW, Paige CJ, Alzheimer C, Harvey RJ, Villmann C.
    J Neurosci; 2017 Aug 16; 37(33):7948-7961. PubMed ID: 28724750
    [Abstract] [Full Text] [Related]

  • 35. Propofol restores the function of "hyperekplexic" mutant glycine receptors in Xenopus oocytes and mice.
    O'Shea SM, Becker L, Weiher H, Betz H, Laube B.
    J Neurosci; 2004 Mar 03; 24(9):2322-7. PubMed ID: 14999083
    [Abstract] [Full Text] [Related]

  • 36. The basic property of Lys385 is important for potentiation of the human α1 glycine receptor by ethanol.
    Castro PA, Figueroa M, Yevenes GE, San Martin LS, Aguayo LG.
    J Pharmacol Exp Ther; 2012 Feb 03; 340(2):339-49. PubMed ID: 22040678
    [Abstract] [Full Text] [Related]

  • 37. Effects of a mutation in the TM2-TM3 linker region of the glycine receptor alpha1 subunit on gating and allosteric modulation.
    Dupre ML, Broyles JM, Mihic SJ.
    Brain Res; 2007 Jun 04; 1152():1-9. PubMed ID: 17434460
    [Abstract] [Full Text] [Related]

  • 38. Zinc potentiation of the glycine receptor chloride channel is mediated by allosteric pathways.
    Lynch JW, Jacques P, Pierce KD, Schofield PR.
    J Neurochem; 1998 Nov 04; 71(5):2159-68. PubMed ID: 9798943
    [Abstract] [Full Text] [Related]

  • 39. Extrinsic factors regulate partial agonist efficacy of strychnine-sensitive glycine receptors.
    Farroni JS, McCool BA.
    BMC Pharmacol; 2004 Aug 09; 4():16. PubMed ID: 15301692
    [Abstract] [Full Text] [Related]

  • 40. Thermophoretic analysis of ligand-specific conformational states of the inhibitory glycine receptor embedded in copolymer nanodiscs.
    Bernhard M, Laube B.
    Sci Rep; 2020 Oct 06; 10(1):16569. PubMed ID: 33024136
    [Abstract] [Full Text] [Related]

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