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Journal Abstract Search

1287 related items for PubMed ID: 27924425

  • 1. Inhibition of NLRP3 Inflammasome Prevents LPS-Induced Inflammatory Hyperalgesia in Mice: Contribution of NF-κB, Caspase-1/11, ASC, NOX, and NOS Isoforms.
    Dolunay A, Senol SP, Temiz-Resitoglu M, Guden DS, Sari AN, Sahan-Firat S, Tunctan B.
    Inflammation; 2017 Apr; 40(2):366-386. PubMed ID: 27924425
    [Abstract] [Full Text] [Related]

  • 2. Soluble epoxide hydrolase inhibitor trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl)urea prevents hyperalgesia through regulating NLRC4 inflammasome-related pro-inflammatory and anti-inflammatory signaling pathways in the lipopolysaccharide-induced pain mouse model.
    Cagli A, Senol SP, Temiz-Resitoglu M, Guden DS, Sari AN, Sahan-Firat S, Tunctan B.
    Drug Dev Res; 2021 Sep; 82(6):815-825. PubMed ID: 33559150
    [Abstract] [Full Text] [Related]

  • 3. Ameliorative effect of selective NLRP3 inflammasome inhibitor MCC950 in an ovalbumin-induced allergic rhinitis murine model.
    Zhang W, Ba G, Tang R, Li M, Lin H.
    Int Immunopharmacol; 2020 Jun; 83():106394. PubMed ID: 32193102
    [Abstract] [Full Text] [Related]

  • 4. Hydrogen-Rich Saline Attenuated Subarachnoid Hemorrhage-Induced Early Brain Injury in Rats by Suppressing Inflammatory Response: Possible Involvement of NF-κB Pathway and NLRP3 Inflammasome.
    Shao A, Wu H, Hong Y, Tu S, Sun X, Wu Q, Zhao Q, Zhang J, Sheng J.
    Mol Neurobiol; 2016 Jul; 53(5):3462-3476. PubMed ID: 26091790
    [Abstract] [Full Text] [Related]

  • 5. Pharmacological inhibition of the NLRP3 inflammasome as a potential target for cancer-induced bone pain.
    Chen SP, Zhou YQ, Wang XM, Sun J, Cao F, HaiSam S, Ye DW, Tian YK.
    Pharmacol Res; 2019 Sep; 147():104339. PubMed ID: 31276771
    [Abstract] [Full Text] [Related]

  • 6. The effects of NLRP3 inflammasome inhibition by MCC950 on LPS-induced pancreatic adenocarcinoma inflammation.
    Yaw ACK, Chan EWL, Yap JKY, Mai CW.
    J Cancer Res Clin Oncol; 2020 Sep; 146(9):2219-2229. PubMed ID: 32507974
    [Abstract] [Full Text] [Related]

  • 7. NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice.
    Mridha AR, Wree A, Robertson AAB, Yeh MM, Johnson CD, Van Rooyen DM, Haczeyni F, Teoh NC, Savard C, Ioannou GN, Masters SL, Schroder K, Cooper MA, Feldstein AE, Farrell GC.
    J Hepatol; 2017 May; 66(5):1037-1046. PubMed ID: 28167322
    [Abstract] [Full Text] [Related]

  • 8. GEN-27 exhibits anti-inflammatory effects by suppressing the activation of NLRP3 inflammasome and NF-κB pathway.
    Hu M, Li X, Zhang J, Yuan Z, Fu Y, Ma X, Ren N.
    Cell Biol Int; 2019 Oct; 43(10):1184-1192. PubMed ID: 30632647
    [Abstract] [Full Text] [Related]

  • 9. Efficacy and Pharmacology of the NLRP3 Inflammasome Inhibitor CP-456,773 (CRID3) in Murine Models of Dermal and Pulmonary Inflammation.
    Primiano MJ, Lefker BA, Bowman MR, Bree AG, Hubeau C, Bonin PD, Mangan M, Dower K, Monks BG, Cushing L, Wang S, Guzova J, Jiao A, Lin LL, Latz E, Hepworth D, Hall JP.
    J Immunol; 2016 Sep 15; 197(6):2421-33. PubMed ID: 27521339
    [Abstract] [Full Text] [Related]

  • 10. Selective NLRP3 inflammasome inhibitor reduces neuroinflammation and improves long-term neurological outcomes in a murine model of traumatic brain injury.
    Xu X, Yin D, Ren H, Gao W, Li F, Sun D, Wu Y, Zhou S, Lyu L, Yang M, Xiong J, Han L, Jiang R, Zhang J.
    Neurobiol Dis; 2018 Sep 15; 117():15-27. PubMed ID: 29859317
    [Abstract] [Full Text] [Related]

  • 11. Contribution of iNOS/sGC/PKG pathway, COX-2, CYP4A1, and gp91(phox) to the protective effect of 5,14-HEDGE, a 20-HETE mimetic, against vasodilation, hypotension, tachycardia, and inflammation in a rat model of septic shock.
    Tunctan B, Korkmaz B, Sari AN, Kacan M, Unsal D, Serin MS, Buharalioglu CK, Sahan-Firat S, Cuez T, Schunck WH, Manthati VL, Falck JR, Malik KU.
    Nitric Oxide; 2013 Sep 01; 33():18-41. PubMed ID: 23684565
    [Abstract] [Full Text] [Related]

  • 12. Inhibiting the NLRP3 inflammasome with MCC950 ameliorates retinal neovascularization and leakage by reversing the IL-1β/IL-18 activation pattern in an oxygen-induced ischemic retinopathy mouse model.
    Sui A, Chen X, Shen J, Demetriades AM, Yao Y, Yao Y, Zhu Y, Shen X, Xie B.
    Cell Death Dis; 2020 Oct 22; 11(10):901. PubMed ID: 33093455
    [Abstract] [Full Text] [Related]

  • 13. Protective effect of combination of anakinra and MCC950 against acute lung injury is achieved through suppression of the NF-κB-mediated-MAPK and NLRP3-caspase pathways.
    Wang X, Chen S, Zhao L, Shi X.
    Int Immunopharmacol; 2021 Aug 22; 97():107506. PubMed ID: 34022766
    [Abstract] [Full Text] [Related]

  • 14. Inhibition of NLRP3 inflammasome ameliorates podocyte damage by suppressing lipid accumulation in diabetic nephropathy.
    Wu M, Yang Z, Zhang C, Shi Y, Han W, Song S, Mu L, Du C, Shi Y.
    Metabolism; 2021 May 22; 118():154748. PubMed ID: 33675822
    [Abstract] [Full Text] [Related]

  • 15. The NLRP3 inflammasome modulates glycolysis by increasing PFKFB3 in an IL-1β-dependent manner in macrophages.
    Finucane OM, Sugrue J, Rubio-Araiz A, Guillot-Sestier MV, Lynch MA.
    Sci Rep; 2019 Mar 11; 9(1):4034. PubMed ID: 30858427
    [Abstract] [Full Text] [Related]

  • 16. Paeonol reduces IL-β production by inhibiting the activation of nucleotide oligomerization domain-like receptor protein-3 inflammasome and nuclear factor-κB in macrophages.
    Chen G, Guo T, Yang L.
    Biochem Cell Biol; 2022 Feb 11; 100(1):28-36. PubMed ID: 34784237
    [Abstract] [Full Text] [Related]

  • 17. Inhibition of the NLRP3-inflammasome as a potential approach for neuroprotection after stroke.
    Ismael S, Zhao L, Nasoohi S, Ishrat T.
    Sci Rep; 2018 Apr 13; 8(1):5971. PubMed ID: 29654318
    [Abstract] [Full Text] [Related]

  • 18. MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition.
    Vande Walle L, Stowe IB, Šácha P, Lee BL, Demon D, Fossoul A, Van Hauwermeiren F, Saavedra PHV, Šimon P, Šubrt V, Kostka L, Stivala CE, Pham VC, Staben ST, Yamazoe S, Konvalinka J, Kayagaki N, Lamkanfi M.
    PLoS Biol; 2019 Sep 13; 17(9):e3000354. PubMed ID: 31525186
    [Abstract] [Full Text] [Related]

  • 19. Guizhi-Shaoyao-Zhimu decoction attenuates monosodium urate crystal-induced inflammation through inactivation of NF-κB and NLRP3 inflammasome.
    Zhou GQ, Chen G, Yang J, Qin WY, Ping J.
    J Ethnopharmacol; 2022 Jan 30; 283():114707. PubMed ID: 34619319
    [Abstract] [Full Text] [Related]

  • 20. Caspase-1/ASC inflammasome-mediated activation of IL-1β-ROS-NF-κB pathway for control of Trypanosoma cruzi replication and survival is dispensable in NLRP3-/- macrophages.
    Dey N, Sinha M, Gupta S, Gonzalez MN, Fang R, Endsley JJ, Luxon BA, Garg NJ.
    PLoS One; 2014 Jan 30; 9(11):e111539. PubMed ID: 25372293
    [Abstract] [Full Text] [Related]

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