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119 related items for PubMed ID: 2794782

  • 1.
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  • 2. Inhibitors of sterol synthesis. Chemical syntheses, properties and effects of 4,4-dimethyl-15-oxygenated sterols on sterol synthesis and on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured mammalian cells.
    Schroepfer GJ, Parish EJ, Tsuda M, Kandutsch AA.
    Chem Phys Lipids; 1988 Jul; 47(3):187-207. PubMed ID: 3168085
    [Abstract] [Full Text] [Related]

  • 3. Inhibitors of sterol synthesis. Chemical synthesis and spectral properties of (25R)-5 alpha-cholest-8(14)-ene-3 beta,15 beta,26-triol, a potential metabolite of 3 beta-hydroxy-5 alpha-cholest-8(14)-en-15-one and its effects on 3-hydroxy-3-methylglutaryl-coenzyme A reductase in CHO-K1 cells.
    Swaminathan S, Pinkerton FD, Wilson WK, Schroepfer GJ.
    Chem Phys Lipids; 1992 May; 61(3):235-42. PubMed ID: 1525963
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  • 4. Inhibitors of sterol biosynthesis. Synthesis and activities of ring C oxygenated sterols.
    Schroepfer GJ, Parish EJ, Kandutsch AA.
    Chem Phys Lipids; 1988 Feb; 46(2):147-54. PubMed ID: 3342458
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  • 5. Inhibitors of sterol synthesis. Chemical synthesis and spectral properties of 3 beta-hydroxy-5 alpha-cholesta-8(14),24-dien-15-one, 3 beta,25-dihydroxy-5 alpha-cholest-8(14)-en-15-one, and 3 beta,24-dihydroxy-5 alpha-cholest-8(14)-en-15-one and their effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in CHO-K1 cells.
    Swaminathan S, Pinkerton FD, Numazawa S, Wilson WK, Schroepfer GJ.
    J Lipid Res; 1992 Oct; 33(10):1503-15. PubMed ID: 1431575
    [Abstract] [Full Text] [Related]

  • 6. Inhibitors of sterol synthesis. Differential effects of 14 alpha-hydroxymethyl-5 alpha-cholest-7-ene-3 beta, 15 alpha-diol and 14 alpha-hydroxymethyl-5 alpha-cholest-6-ene-3 beta, 15 alpha-diol on sterol synthesis in cell-free homogenates of rat liver.
    Miller LR, Pascal RA, Schroepfer GJ.
    J Biol Chem; 1981 Aug 10; 256(15):8085-91. PubMed ID: 7263642
    [Abstract] [Full Text] [Related]

  • 7. Inhibitors of sterol synthesis. Characterization of beta,gamma-unsaturated analogs of 3 beta-hydroxy-5 alpha-cholest-8(14)-en-15-one and their effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in CHO-K1 cells.
    Wilson WK, Wheeler ME, Pinkerton FD, St Pyrek J, Schroepfer GJ.
    J Lipid Res; 1991 Jul 10; 32(7):1215-27. PubMed ID: 1940644
    [Abstract] [Full Text] [Related]

  • 8. Inhibitors of sterol synthesis. Synthesis and spectral properties of 3 beta-hydroxy-5 alpha-cholestan-15-one and its 17 beta-epimer and their effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity.
    Siddiqui AU, Wilson WK, Parish EJ, Gerst N, Pinkerton FD, Schroepfer GJ.
    Chem Phys Lipids; 1994 Oct 20; 74(1):1-15. PubMed ID: 7820900
    [Abstract] [Full Text] [Related]

  • 9. Inhibitors of sterol synthesis. Chemical syntheses and spectral properties of 26-oxygenated derivatives of 3 beta-hydroxy-5 alpha-cholest-8(14)-en-15-one and their effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in CHO-K1 cells.
    Siddiqui AU, Wilson WK, Ruecker KE, Pinkerton FD, Schroepfer GJ.
    Chem Phys Lipids; 1992 Nov 20; 63(1-2):77-90. PubMed ID: 1486662
    [Abstract] [Full Text] [Related]

  • 10. Inhibitors of sterol synthesis. Submicromolar 14 alpha-ethyl-5 alpha-cholest-7-ene-3 beta, 15 alpha-diol causes a major modification of the sterol composition of CHO-K1 cells and a marked change in cell morphology.
    Izumi A, Pinkerton FD, Nelson SO, Pyrek JS, Neill PJ, Smith JH, Schroepfer GJ.
    J Lipid Res; 1994 Jul 20; 35(7):1251-66. PubMed ID: 7964186
    [Abstract] [Full Text] [Related]

  • 11. 15 beta-Methyl-5 alpha,14 beta-cholest-7-ene-3 beta,15 alpha-diol. Synthesis, structure, and inhibition of sterol synthesis in animal cells.
    Schroepfer GJ, Parish EJ, Kandutsch AA, Bowen ST, Quiocho FA.
    Biochem Int; 1987 Aug 20; 15(2):403-8. PubMed ID: 3435532
    [Abstract] [Full Text] [Related]

  • 12. Inhibitors of sterol synthesis. Chemical synthesis of 7 alpha-ethyl and 16 alpha-ethyl derivatives of delta 8(14)-15-oxygenated sterols and their effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase in CHO-K1 cells.
    Kim HS, Wilson WK, Kirkpatrick ND, Pinkerton FD, Swaminathan S, Hylarides MD, Schroepfer GJ.
    Chem Phys Lipids; 1992 Jul 20; 62(1):55-67. PubMed ID: 1423803
    [Abstract] [Full Text] [Related]

  • 13. Inhibitors of sterol synthesis. Chemical synthesis, structure, and biological activities of (25R)-3 beta,26-dihydroxy-5 alpha-cholest-8(14)-en-15-one, a metabolite of 3 beta-hydroxy-5 alpha-cholest-8(14)-en-15-one.
    Kim HS, Wilson WK, Needleman DH, Pinkerton FD, Wilson DK, Quiocho FA, Schroepfer GJ.
    J Lipid Res; 1989 Feb 20; 30(2):247-61. PubMed ID: 2715729
    [Abstract] [Full Text] [Related]

  • 14. Inhibitors of sterol synthesis. Chemical synthesis and properties of 3 beta-hydroxy-25,26,26,26,27,27,27-heptafluoro-5 alpha-cholest-8(14)-en-15-one and 25,26,26,26,27,27,27-heptafluorocholesterol and their effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured mammalian cells.
    Swaminathan S, Wilson WK, Pinkerton FD, Gerst N, Ramser M, Schroepfer GJ.
    J Lipid Res; 1993 Oct 20; 34(10):1805-23. PubMed ID: 8245728
    [Abstract] [Full Text] [Related]

  • 15. 15-Oxygenated sterols with the unnatural cis-C-D ring junction. Studies of the metabolism of 5 alpha,14 beta-cholest-7-ene-3 beta,15 alpha-diol and 5 alpha,14 beta-cholest-7-ene-3 beta,15 beta-diol.
    Pascal RA, Schroepfer GJ.
    J Biol Chem; 1980 Apr 25; 255(8):3565-70. PubMed ID: 7364756
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  • 19. Inhibitors of sterol synthesis. Synthesis and spectral characterization of fatty acids esters of 5 alpha-cholest-8(14)-en-3 beta-ol-15-one.
    St Pyrek J, Schroepfer GJ.
    J Lipid Res; 1987 Nov 25; 28(11):1308-12. PubMed ID: 3430061
    [Abstract] [Full Text] [Related]

  • 20. Inhibitors of sterol synthesis. 14 alpha-ethyl-5 alpha-cholest-7-ene-3 beta,15 alpha-diol induces changes in the sterol composition and the morphology of CHO-K1 cells.
    Pinkerton FD, Izumi A, Schroepfer GJ.
    Biochem Biophys Res Commun; 1988 Nov 30; 157(1):359-63. PubMed ID: 3196343
    [Abstract] [Full Text] [Related]

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