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371 related items for PubMed ID: 27965414

  • 1. Overlapping roles for PARP1 and PARP2 in the recruitment of endogenous XRCC1 and PNKP into oxidized chromatin.
    Hanzlikova H, Gittens W, Krejcikova K, Zeng Z, Caldecott KW.
    Nucleic Acids Res; 2017 Mar 17; 45(5):2546-2557. PubMed ID: 27965414
    [Abstract] [Full Text] [Related]

  • 2. XRCC1 mutation is associated with PARP1 hyperactivation and cerebellar ataxia.
    Hoch NC, Hanzlikova H, Rulten SL, Tétreault M, Komulainen E, Ju L, Hornyak P, Zeng Z, Gittens W, Rey SA, Staras K, Mancini GM, McKinnon PJ, Wang ZQ, Wagner JD, Care4Rare Canada Consortium, Yoon G, Caldecott KW.
    Nature; 2017 Jan 05; 541(7635):87-91. PubMed ID: 28002403
    [Abstract] [Full Text] [Related]

  • 3. Dispensability of HPF1 for cellular removal of DNA single-strand breaks.
    Hrychova K, Burdova K, Polackova Z, Giamaki D, Valtorta B, Brazina J, Krejcikova K, Kuttichova B, Caldecott KW, Hanzlikova H.
    Nucleic Acids Res; 2024 Oct 14; 52(18):10986-10998. PubMed ID: 39162207
    [Abstract] [Full Text] [Related]

  • 4. XRCC1-mediated repair of strand breaks independent of PNKP binding.
    Horton JK, Stefanick DF, Zhao ML, Janoshazi AK, Gassman NR, Seddon HJ, Wilson SH.
    DNA Repair (Amst); 2017 Dec 14; 60():52-63. PubMed ID: 29100039
    [Abstract] [Full Text] [Related]

  • 5. Common and unique genetic interactions of the poly(ADP-ribose) polymerases PARP1 and PARP2 with DNA double-strand break repair pathways.
    Ghosh R, Roy S, Kamyab J, Danzter F, Franco S.
    DNA Repair (Amst); 2016 Sep 14; 45():56-62. PubMed ID: 27373144
    [Abstract] [Full Text] [Related]

  • 6. Temporal recruitment of base excision DNA repair factors in living cells in response to different micro-irradiation DNA damage protocols.
    Zhao ML, Stefanick DF, Nadalutti CA, Beard WA, Wilson SH, Horton JK.
    DNA Repair (Amst); 2023 Jun 14; 126():103486. PubMed ID: 37028218
    [Abstract] [Full Text] [Related]

  • 7. The Rev1 interacting region (RIR) motif in the scaffold protein XRCC1 mediates a low-affinity interaction with polynucleotide kinase/phosphatase (PNKP) during DNA single-strand break repair.
    Breslin C, Mani RS, Fanta M, Hoch N, Weinfeld M, Caldecott KW.
    J Biol Chem; 2017 Sep 29; 292(39):16024-16031. PubMed ID: 28821613
    [Abstract] [Full Text] [Related]

  • 8. Efficient Single-Strand Break Repair Requires Binding to Both Poly(ADP-Ribose) and DNA by the Central BRCT Domain of XRCC1.
    Polo LM, Xu Y, Hornyak P, Garces F, Zeng Z, Hailstone R, Matthews SJ, Caldecott KW, Oliver AW, Pearl LH.
    Cell Rep; 2019 Jan 15; 26(3):573-581.e5. PubMed ID: 30650352
    [Abstract] [Full Text] [Related]

  • 9. A requirement for PARP-1 for the assembly or stability of XRCC1 nuclear foci at sites of oxidative DNA damage.
    El-Khamisy SF, Masutani M, Suzuki H, Caldecott KW.
    Nucleic Acids Res; 2003 Oct 01; 31(19):5526-33. PubMed ID: 14500814
    [Abstract] [Full Text] [Related]

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  • 11. Temporal dynamics of base excision/single-strand break repair protein complex assembly/disassembly are modulated by the PARP/NAD+/SIRT6 axis.
    Koczor CA, Saville KM, Andrews JF, Clark J, Fang Q, Li J, Al-Rahahleh RQ, Ibrahim M, McClellan S, Makarov MV, Migaud ME, Sobol RW.
    Cell Rep; 2021 Nov 02; 37(5):109917. PubMed ID: 34731617
    [Abstract] [Full Text] [Related]

  • 12. The CSB chromatin remodeler regulates PARP1- and PARP2-mediated single-strand break repair at actively transcribed DNA regions.
    Bilkis R, Lake RJ, Cooper KL, Tomkinson A, Fan HY.
    Nucleic Acids Res; 2023 Aug 11; 51(14):7342-7356. PubMed ID: 37326017
    [Abstract] [Full Text] [Related]

  • 13. Functional Roles of PARP2 in Assembling Protein-Protein Complexes Involved in Base Excision DNA Repair.
    Vasil'eva I, Moor N, Anarbaev R, Kutuzov M, Lavrik O.
    Int J Mol Sci; 2021 Apr 28; 22(9):. PubMed ID: 33925170
    [Abstract] [Full Text] [Related]

  • 14. A quantitative assay reveals ligand specificity of the DNA scaffold repair protein XRCC1 and efficient disassembly of complexes of XRCC1 and the poly(ADP-ribose) polymerase 1 by poly(ADP-ribose) glycohydrolase.
    Kim IK, Stegeman RA, Brosey CA, Ellenberger T.
    J Biol Chem; 2015 Feb 06; 290(6):3775-83. PubMed ID: 25477519
    [Abstract] [Full Text] [Related]

  • 15. Poly (ADP-ribose) polymerase (PARP) is not involved in base excision repair but PARP inhibition traps a single-strand intermediate.
    Ström CE, Johansson F, Uhlén M, Szigyarto CA, Erixon K, Helleday T.
    Nucleic Acids Res; 2011 Apr 06; 39(8):3166-75. PubMed ID: 21183466
    [Abstract] [Full Text] [Related]

  • 16. The XRCC1 phosphate-binding pocket binds poly (ADP-ribose) and is required for XRCC1 function.
    Breslin C, Hornyak P, Ridley A, Rulten SL, Hanzlikova H, Oliver AW, Caldecott KW.
    Nucleic Acids Res; 2015 Aug 18; 43(14):6934-44. PubMed ID: 26130715
    [Abstract] [Full Text] [Related]

  • 17. DNA ligase III acts as a DNA strand break sensor in the cellular orchestration of DNA strand break repair.
    Abdou I, Poirier GG, Hendzel MJ, Weinfeld M.
    Nucleic Acids Res; 2015 Jan 18; 43(2):875-92. PubMed ID: 25539916
    [Abstract] [Full Text] [Related]

  • 18. XRCC1 mediates PARP1- and PAR-dependent recruitment of PARP2 to DNA damage sites.
    Lin X, Leung KSK, Wolfe KF, Lee BJ, Zha S.
    bioRxiv; 2024 May 17. PubMed ID: 38798615
    [Abstract] [Full Text] [Related]

  • 19. Distinct spatiotemporal patterns and PARP dependence of XRCC1 recruitment to single-strand break and base excision repair.
    Campalans A, Kortulewski T, Amouroux R, Menoni H, Vermeulen W, Radicella JP.
    Nucleic Acids Res; 2013 Mar 01; 41(5):3115-29. PubMed ID: 23355608
    [Abstract] [Full Text] [Related]

  • 20. Damage response of XRCC1 at sites of DNA single strand breaks is regulated by phosphorylation and ubiquitylation after degradation of poly(ADP-ribose).
    Wei L, Nakajima S, Hsieh CL, Kanno S, Masutani M, Levine AS, Yasui A, Lan L.
    J Cell Sci; 2013 Oct 01; 126(Pt 19):4414-23. PubMed ID: 23868975
    [Abstract] [Full Text] [Related]

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