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Journal Abstract Search


263 related items for PubMed ID: 27977755

  • 1. Concurrent Treatment with Taxifolin and Cilostazol on the Lowering of β-Amyloid Accumulation and Neurotoxicity via the Suppression of P-JAK2/P-STAT3/NF-κB/BACE1 Signaling Pathways.
    Park SY, Kim HY, Park HJ, Shin HK, Hong KW, Kim CD.
    PLoS One; 2016; 11(12):e0168286. PubMed ID: 27977755
    [Abstract] [Full Text] [Related]

  • 2. Cilostazol Modulates Autophagic Degradation of β-Amyloid Peptide via SIRT1-Coupled LKB1/AMPKα Signaling in Neuronal Cells.
    Park SY, Lee HR, Lee WS, Shin HK, Kim HY, Hong KW, Kim CD.
    PLoS One; 2016; 11(8):e0160620. PubMed ID: 27494711
    [Abstract] [Full Text] [Related]

  • 3. Cilostazol suppresses β-amyloid production by activating a disintegrin and metalloproteinase 10 via the upregulation of SIRT1-coupled retinoic acid receptor-β.
    Lee HR, Shin HK, Park SY, Kim HY, Lee WS, Rhim BY, Hong KW, Kim CD.
    J Neurosci Res; 2014 Nov; 92(11):1581-90. PubMed ID: 24903973
    [Abstract] [Full Text] [Related]

  • 4. Increased NF-κB signalling up-regulates BACE1 expression and its therapeutic potential in Alzheimer's disease.
    Chen CH, Zhou W, Liu S, Deng Y, Cai F, Tone M, Tone Y, Tong Y, Song W.
    Int J Neuropsychopharmacol; 2012 Feb; 15(1):77-90. PubMed ID: 21329555
    [Abstract] [Full Text] [Related]

  • 5. Cilostazol Upregulates Autophagy via SIRT1 Activation: Reducing Amyloid-β Peptide and APP-CTFβ Levels in Neuronal Cells.
    Lee HR, Shin HK, Park SY, Kim HY, Bae SS, Lee WS, Rhim BY, Hong KW, Kim CD.
    PLoS One; 2015 Feb; 10(8):e0134486. PubMed ID: 26244661
    [Abstract] [Full Text] [Related]

  • 6. Attenuation of β-amyloid-induced tauopathy via activation of CK2α/SIRT1: targeting for cilostazol.
    Lee HR, Shin HK, Park SY, Kim HY, Lee WS, Rhim BY, Hong KW, Kim CD.
    J Neurosci Res; 2014 Feb; 92(2):206-17. PubMed ID: 24254769
    [Abstract] [Full Text] [Related]

  • 7. [Mechanism of ginsenoside Rg1 regulating the activity of β secretase in N2a/APP695 cells].
    Chen LM, Lin N, Zhang J, Zhu YG, Chen XC.
    Zhonghua Yi Xue Za Zhi; 2012 Feb 07; 92(5):330-5. PubMed ID: 22490838
    [Abstract] [Full Text] [Related]

  • 8. Carbon monoxide attenuates amyloidogenesis via down-regulation of NF-κB-mediated BACE1 gene expression.
    Kim HJ, Joe Y, Chen Y, Park GH, Kim UH, Chung HT.
    Aging Cell; 2019 Feb 07; 18(1):e12864. PubMed ID: 30411846
    [Abstract] [Full Text] [Related]

  • 9. Leptin attenuates BACE1 expression and amyloid-β genesis via the activation of SIRT1 signaling pathway.
    Marwarha G, Raza S, Meiers C, Ghribi O.
    Biochim Biophys Acta; 2014 Sep 07; 1842(9):1587-95. PubMed ID: 24874077
    [Abstract] [Full Text] [Related]

  • 10. Hydroxy-safflor yellow A attenuates Aβ₁₋₄₂-induced inflammation by modulating the JAK2/STAT3/NF-κB pathway.
    Zhang ZH, Yu LJ, Hui XC, Wu ZZ, Yin KL, Yang H, Xu Y.
    Brain Res; 2014 May 14; 1563():72-80. PubMed ID: 24690200
    [Abstract] [Full Text] [Related]

  • 11. Protection by cilostazol against amyloid-β(1-40)-induced suppression of viability and neurite elongation through activation of CK2α in HT22 mouse hippocampal cells.
    Lee HR, Park SY, Kim HY, Shin HK, Lee WS, Rhim BY, Hong KW, Kim CD.
    J Neurosci Res; 2012 Aug 14; 90(8):1566-76. PubMed ID: 22422579
    [Abstract] [Full Text] [Related]

  • 12. Convergence of alpha 7 nicotinic acetylcholine receptor-activated pathways for anti-apoptosis and anti-inflammation: central role for JAK2 activation of STAT3 and NF-kappaB.
    Marrero MB, Bencherif M.
    Brain Res; 2009 Feb 23; 1256():1-7. PubMed ID: 19063868
    [Abstract] [Full Text] [Related]

  • 13. Inhibitory effect of ent-Sauchinone on amyloidogenesis via inhibition of STAT3-mediated NF-κB activation in cultured astrocytes and microglial BV-2 cells.
    Song SY, Jung YY, Hwang CJ, Lee HP, Sok CH, Kim JH, Lee SM, Seo HO, Hyun BK, Choi DY, Han SB, Ham YW, Hwang BY, Hong JT.
    J Neuroinflammation; 2014 Jul 02; 11():118. PubMed ID: 24985096
    [Abstract] [Full Text] [Related]

  • 14. Tripchlorolide Attenuates β-amyloid Generation via Suppressing PPARγ-Regulated BACE1 Activity in N2a/APP695 Cells.
    Lin N, Chen LM, Pan XD, Zhu YG, Zhang J, Shi YQ, Chen XC.
    Mol Neurobiol; 2016 Nov 02; 53(9):6397-6406. PubMed ID: 26582466
    [Abstract] [Full Text] [Related]

  • 15. Palmitate-induced C/EBP homologous protein activation leads to NF-κB-mediated increase in BACE1 activity and amyloid beta genesis.
    Marwarha G, Schommer J, Lund J, Schommer T, Ghribi O.
    J Neurochem; 2018 Mar 02; 144(6):761-779. PubMed ID: 29315574
    [Abstract] [Full Text] [Related]

  • 16. Chicoric acid supplementation prevents systemic inflammation-induced memory impairment and amyloidogenesis via inhibition of NF-κB.
    Liu Q, Chen Y, Shen C, Xiao Y, Wang Y, Liu Z, Liu X.
    FASEB J; 2017 Apr 02; 31(4):1494-1507. PubMed ID: 28003341
    [Abstract] [Full Text] [Related]

  • 17. Ginsenoside Rg1 attenuates β-amyloid generation via suppressing PPARγ-regulated BACE1 activity in N2a-APP695 cells.
    Chen LM, Lin ZY, Zhu YG, Lin N, Zhang J, Pan XD, Chen XC.
    Eur J Pharmacol; 2012 Jan 30; 675(1-3):15-21. PubMed ID: 22166376
    [Abstract] [Full Text] [Related]

  • 18. Melatonin ameliorates Aβ42 -induced alteration of βAPP-processing secretases via the melatonin receptor through the Pin1/GSK3β/NF-κB pathway in SH-SY5Y cells.
    Chinchalongporn V, Shukla M, Govitrapong P.
    J Pineal Res; 2018 May 30; 64(4):e12470. PubMed ID: 29352484
    [Abstract] [Full Text] [Related]

  • 19. Aβ1-42-mediated down-regulation of Uch-L1 is dependent on NF-κB activation and impaired BACE1 lysosomal degradation.
    Guglielmotto M, Monteleone D, Boido M, Piras A, Giliberto L, Borghi R, Vercelli A, Fornaro M, Tabaton M, Tamagno E.
    Aging Cell; 2012 Oct 30; 11(5):834-44. PubMed ID: 22726800
    [Abstract] [Full Text] [Related]

  • 20. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
    Deng Y, Wang Z, Wang R, Zhang X, Zhang S, Wu Y, Staufenbiel M, Cai F, Song W.
    Eur J Neurosci; 2013 Jun 30; 37(12):1962-9. PubMed ID: 23773065
    [Abstract] [Full Text] [Related]


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