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Journal Abstract Search

329 related items for PubMed ID: 28012162

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  • 4. Brivaracetam: Rationale for discovery and preclinical profile of a selective SV2A ligand for epilepsy treatment.
    Klitgaard H, Matagne A, Nicolas JM, Gillard M, Lamberty Y, De Ryck M, Kaminski RM, Leclercq K, Niespodziany I, Wolff C, Wood M, Hannestad J, Kervyn S, Kenda B.
    Epilepsia; 2016 Apr; 57(4):538-48. PubMed ID: 26920914
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  • 5. A single-center, open-label positron emission tomography study to evaluate brivaracetam and levetiracetam synaptic vesicle glycoprotein 2A binding in healthy volunteers.
    Finnema SJ, Rossano S, Naganawa M, Henry S, Gao H, Pracitto R, Maguire RP, Mercier J, Kervyn S, Nicolas JM, Klitgaard H, DeBruyn S, Otoul C, Martin P, Muglia P, Matuskey D, Nabulsi NB, Huang Y, Kaminski RM, Hannestad J, Stockis A, Carson RE.
    Epilepsia; 2019 May; 60(5):958-967. PubMed ID: 30924924
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  • 7. The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam.
    Lynch BA, Lambeng N, Nocka K, Kensel-Hammes P, Bajjalieh SM, Matagne A, Fuks B.
    Proc Natl Acad Sci U S A; 2004 Jun 29; 101(26):9861-6. PubMed ID: 15210974
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  • 9. Pharmacological Profile of the Novel Antiepileptic Drug Candidate Padsevonil: Interactions with Synaptic Vesicle 2 Proteins and the GABAA Receptor.
    Wood M, Daniels V, Provins L, Wolff C, Kaminski RM, Gillard M.
    J Pharmacol Exp Ther; 2020 Jan 29; 372(1):1-10. PubMed ID: 31619465
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  • 10. Modulation of the conformational state of the SV2A protein by an allosteric mechanism as evidenced by ligand binding assays.
    Daniels V, Wood M, Leclercq K, Kaminski RM, Gillard M.
    Br J Pharmacol; 2013 Jul 29; 169(5):1091-101. PubMed ID: 23530581
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  • 13. Binding characteristics of levetiracetam to synaptic vesicle protein 2A (SV2A) in human brain and in CHO cells expressing the human recombinant protein.
    Gillard M, Chatelain P, Fuks B.
    Eur J Pharmacol; 2006 Apr 24; 536(1-2):102-8. PubMed ID: 16556440
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  • 15. Interaction of Approved Drugs with Synaptic Vesicle Protein 2A.
    Danish A, Namasivayam V, Schiedel AC, Müller CE.
    Arch Pharm (Weinheim); 2017 Apr 24; 350(3-4):. PubMed ID: 28220535
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  • 17. Favorable adverse effect profile of brivaracetam vs levetiracetam in a preclinical model.
    Sanon NT, Gagné J, Wolf DC, Aboulamer S, Bosoi CM, Simard A, Messiet E, Desgent S, Carmant L.
    Epilepsy Behav; 2018 Feb 24; 79():117-125. PubMed ID: 29287214
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  • 19. Anti-convulsive and anti-epileptic properties of brivaracetam (ucb 34714), a high-affinity ligand for the synaptic vesicle protein, SV2A.
    Matagne A, Margineanu DG, Kenda B, Michel P, Klitgaard H.
    Br J Pharmacol; 2008 Aug 24; 154(8):1662-71. PubMed ID: 18500360
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  • 20. Tolerability, efficacy and retention rate of Brivaracetam in patients previously treated with Levetiracetam: A monocenter retrospective outcome analysis.
    Hirsch M, Hintz M, Specht A, Schulze-Bonhage A.
    Seizure; 2018 Oct 24; 61():98-103. PubMed ID: 30118932
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