These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

372 related items for PubMed ID: 28017718

  • 1. Maturation and processing of the amyloid precursor protein is regulated by the potassium/sodium hyperpolarization-activated cyclic nucleotide-gated ion channel 2 (HCN2).
    Frykman S, Inoue M, Ikeda A, Teranishi Y, Kihara T, Lundgren JL, Yamamoto NG, Bogdanovic N, Winblad B, Schedin-Weiss S, Tjernberg LO.
    Biochem Biophys Res Commun; 2017 Jan 29; 483(1):352-358. PubMed ID: 28017718
    [Abstract] [Full Text] [Related]

  • 2. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
    Deng Y, Wang Z, Wang R, Zhang X, Zhang S, Wu Y, Staufenbiel M, Cai F, Song W.
    Eur J Neurosci; 2013 Jun 29; 37(12):1962-9. PubMed ID: 23773065
    [Abstract] [Full Text] [Related]

  • 3. Monoamine oxidase B is elevated in Alzheimer disease neurons, is associated with γ-secretase and regulates neuronal amyloid β-peptide levels.
    Schedin-Weiss S, Inoue M, Hromadkova L, Teranishi Y, Yamamoto NG, Wiehager B, Bogdanovic N, Winblad B, Sandebring-Matton A, Frykman S, Tjernberg LO.
    Alzheimers Res Ther; 2017 Aug 01; 9(1):57. PubMed ID: 28764767
    [Abstract] [Full Text] [Related]

  • 4. The C-terminal fragment of the Alzheimer's disease amyloid protein precursor is degraded by a proteasome-dependent mechanism distinct from gamma-secretase.
    Nunan J, Shearman MS, Checler F, Cappai R, Evin G, Beyreuther K, Masters CL, Small DH.
    Eur J Biochem; 2001 Oct 01; 268(20):5329-36. PubMed ID: 11606195
    [Abstract] [Full Text] [Related]

  • 5.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 6. Activation of peroxisome proliferator-activated receptor α stimulates ADAM10-mediated proteolysis of APP.
    Corbett GT, Gonzalez FJ, Pahan K.
    Proc Natl Acad Sci U S A; 2015 Jul 07; 112(27):8445-50. PubMed ID: 26080426
    [Abstract] [Full Text] [Related]

  • 7. APP-BACE1 Interaction and Intracellular Localization Regulate Aβ Production in iPSC-Derived Cortical Neurons.
    Roselli S, Satir TM, Camacho R, Fruhwürth S, Bergström P, Zetterberg H, Agholme L.
    Cell Mol Neurobiol; 2023 Oct 07; 43(7):3653-3668. PubMed ID: 37355492
    [Abstract] [Full Text] [Related]

  • 8. Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets.
    Evin G, Zhu A, Holsinger RM, Masters CL, Li QX.
    J Neurosci Res; 2003 Nov 01; 74(3):386-92. PubMed ID: 14598315
    [Abstract] [Full Text] [Related]

  • 9. The A673T mutation in the amyloid precursor protein reduces the production of β-amyloid protein from its β-carboxyl terminal fragment in cells.
    Kokawa A, Ishihara S, Fujiwara H, Nobuhara M, Iwata M, Ihara Y, Funamoto S.
    Acta Neuropathol Commun; 2015 Nov 04; 3():66. PubMed ID: 26531305
    [Abstract] [Full Text] [Related]

  • 10. The Alzheimer's Disease γ-Secretase Generates Higher 42:40 Ratios for β-Amyloid Than for p3 Peptides.
    Siegel G, Gerber H, Koch P, Bruestle O, Fraering PC, Rajendran L.
    Cell Rep; 2017 Jun 06; 19(10):1967-1976. PubMed ID: 28591569
    [Abstract] [Full Text] [Related]

  • 11. Decrease in brain soluble amyloid precursor protein β (sAPPβ) in Alzheimer's disease cortex.
    Wu G, Sankaranarayanan S, Hsieh SH, Simon AJ, Savage MJ.
    J Neurosci Res; 2011 Jun 06; 89(6):822-32. PubMed ID: 21433051
    [Abstract] [Full Text] [Related]

  • 12. TFEB-mediated Enhancement of the Autophagy-lysosomal Pathway Dually Modulates the Process of Amyloid β-Protein Generation in Neurons.
    Yamamoto F, Taniguchi K, Mamada N, Tamaoka A, Kametani F, Lakshmana MK, Araki W.
    Neuroscience; 2019 Mar 15; 402():11-22. PubMed ID: 30677488
    [Abstract] [Full Text] [Related]

  • 13. Bispecific Antibody Fragment Targeting APP and Inducing α-Site Cleavage Restores Neuronal Health in an Alzheimer's Mouse Model.
    He P, Xin W, Schulz P, Sierks MR.
    Mol Neurobiol; 2019 Nov 15; 56(11):7420-7432. PubMed ID: 31041656
    [Abstract] [Full Text] [Related]

  • 14. RAGE mediates Aβ accumulation in a mouse model of Alzheimer's disease via modulation of β- and γ-secretase activity.
    Fang F, Yu Q, Arancio O, Chen D, Gore SS, Yan SS, Yan SF.
    Hum Mol Genet; 2018 Mar 15; 27(6):1002-1014. PubMed ID: 29329433
    [Abstract] [Full Text] [Related]

  • 15. RNA interference silencing of the adaptor molecules ShcC and Fe65 differentially affect amyloid precursor protein processing and Abeta generation.
    Xie Z, Dong Y, Maeda U, Xia W, Tanzi RE.
    J Biol Chem; 2007 Feb 16; 282(7):4318-4325. PubMed ID: 17170108
    [Abstract] [Full Text] [Related]

  • 16. Amyloid precursor protein compartmentalization restricts beta-amyloid production: therapeutic targets based on BACE compartmentalization.
    Gandhi S, Refolo LM, Sambamurti K.
    J Mol Neurosci; 2004 Feb 16; 24(1):137-43. PubMed ID: 15314262
    [Abstract] [Full Text] [Related]

  • 17. A novel gamma -secretase assay based on detection of the putative C-terminal fragment-gamma of amyloid beta protein precursor.
    Pinnix I, Musunuru U, Tun H, Sridharan A, Golde T, Eckman C, Ziani-Cherif C, Onstead L, Sambamurti K.
    J Biol Chem; 2001 Jan 05; 276(1):481-7. PubMed ID: 11035007
    [Abstract] [Full Text] [Related]

  • 18. Proteasome-mediated degradation of the C-terminus of the Alzheimer's disease beta-amyloid protein precursor: effect of C-terminal truncation on production of beta-amyloid protein.
    Nunan J, Williamson NA, Hill AF, Sernee MF, Masters CL, Small DH.
    J Neurosci Res; 2003 Nov 01; 74(3):378-85. PubMed ID: 14598314
    [Abstract] [Full Text] [Related]

  • 19. Hyperpolarization-activated cyclic nucleotide gated channels: a potential molecular link between epileptic seizures and Aβ generation in Alzheimer's disease.
    Saito Y, Inoue T, Zhu G, Kimura N, Okada M, Nishimura M, Kimura N, Murayama S, Kaneko S, Shigemoto R, Imoto K, Suzuki T.
    Mol Neurodegener; 2012 Oct 03; 7():50. PubMed ID: 23034178
    [Abstract] [Full Text] [Related]

  • 20. APP overexpression in the absence of NPC1 exacerbates metabolism of amyloidogenic proteins of Alzheimer's disease.
    Maulik M, Peake K, Chung J, Wang Y, Vance JE, Kar S.
    Hum Mol Genet; 2015 Dec 15; 24(24):7132-50. PubMed ID: 26433932
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 19.